JPS53103464A - Prostaglandin x analogues and process for their preparation - Google Patents

Prostaglandin x analogues and process for their preparation

Info

Publication number
JPS53103464A
JPS53103464A JP1714177A JP1714177A JPS53103464A JP S53103464 A JPS53103464 A JP S53103464A JP 1714177 A JP1714177 A JP 1714177A JP 1714177 A JP1714177 A JP 1714177A JP S53103464 A JPS53103464 A JP S53103464A
Authority
JP
Japan
Prior art keywords
prostaglandin
analogues
preparation
coordination
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1714177A
Other languages
Japanese (ja)
Other versions
JPS6131107B2 (en
Inventor
Masaki Hayashi
Yoshinobu Arai
Yoshitaka Konishi
Katsuichi Shimoji
Shuichi Ouchida
Hiroyuki Ito
Hirohisa Wakatsuka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Priority to JP1714177A priority Critical patent/JPS53103464A/en
Priority to US05/878,571 priority patent/US4178367A/en
Priority to GB6675/78A priority patent/GB1598953A/en
Priority to DE19782807178 priority patent/DE2807178A1/en
Priority to FR7804693A priority patent/FR2381043A1/en
Publication of JPS53103464A publication Critical patent/JPS53103464A/en
Publication of JPS6131107B2 publication Critical patent/JPS6131107B2/ja
Granted legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)

Abstract

PURPOSE: Prostaglandin X analogues I[Y is trans-vinylene or ethylene;R' is H or 1-12 alkyl;R2 is H, methyl or ethyl;R3 is a direct bond or 1-4C alkylene; R4 is H, 1-8C alkyl, substd or nonsubstd 4-7C cycloalkyl, etc.; the dotted line is α-or β-coordination(S or R coordination) or their mixture; the double bond between 5 and 6-position is Z] and their nontoxic salts (R' is H), e.g. (5Z, 13E)-(9α,11α, 15α)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dienoic acid methylester.
COPYRIGHT: (C)1978,JPO&Japio
JP1714177A 1977-02-21 1977-02-21 Prostaglandin x analogues and process for their preparation Granted JPS53103464A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP1714177A JPS53103464A (en) 1977-02-21 1977-02-21 Prostaglandin x analogues and process for their preparation
US05/878,571 US4178367A (en) 1977-02-21 1978-02-16 Prostaglandin I2 analogues
GB6675/78A GB1598953A (en) 1977-02-21 1978-02-20 Prostaglandin analogues
DE19782807178 DE2807178A1 (en) 1977-02-21 1978-02-20 PROSTAGLANDIN ANALOGS
FR7804693A FR2381043A1 (en) 1977-02-21 1978-02-20 NEW PROSTAGLANDIN ANALOGUES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1714177A JPS53103464A (en) 1977-02-21 1977-02-21 Prostaglandin x analogues and process for their preparation

Publications (2)

Publication Number Publication Date
JPS53103464A true JPS53103464A (en) 1978-09-08
JPS6131107B2 JPS6131107B2 (en) 1986-07-17

Family

ID=11935719

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1714177A Granted JPS53103464A (en) 1977-02-21 1977-02-21 Prostaglandin x analogues and process for their preparation

Country Status (1)

Country Link
JP (1) JPS53103464A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55100376A (en) * 1979-01-25 1980-07-31 Hoechst Ag Novel analogue of prostacycline and its manufacture
JPS6130554A (en) * 1984-07-23 1986-02-12 Ono Pharmaceut Co Ltd Isomer of prostaglandin-mimic compound having specific steric configuration, and remedy containing said isomer as active component

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55100376A (en) * 1979-01-25 1980-07-31 Hoechst Ag Novel analogue of prostacycline and its manufacture
JPS6130554A (en) * 1984-07-23 1986-02-12 Ono Pharmaceut Co Ltd Isomer of prostaglandin-mimic compound having specific steric configuration, and remedy containing said isomer as active component

Also Published As

Publication number Publication date
JPS6131107B2 (en) 1986-07-17

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