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Ono Pharmaceutical Co Ltd
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Ono Pharmaceutical Co Ltd
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Application filed by Ono Pharmaceutical Co LtdfiledCriticalOno Pharmaceutical Co Ltd
Priority to JP5933577ApriorityCriticalpatent/JPS53144565A/en
Publication of JPS53144565ApublicationCriticalpatent/JPS53144565A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
PURPOSE: Prostaglandin I2 analogous cpds. I[Y is trans-vinylene or ethylene;R1 is H or 1-12Clinear or branched alkyl;R2 is H methyl or ethyl;R3 is a direct bond or 1-4C linear or branched alkylene;R4 is H, 1-8C linear or branched alkyl, etc.;the dotted line is α(S)-orβ(R)-Coordinatination], their cyclotextrin inclusion cpds. and their non toxic acid salt (R1 is H), e.g. (13E)(9α, 11α, 15S) 6,9-epoxy-11, 15-dihydroxyprosta-6,13-dienoic acid methylester.
COPYRIGHT: (C)1978,JPO&Japio
JP5933577A1977-05-241977-05-24Prostaglandin i2 analogous compounds and process for their preparation
PendingJPS53144565A
(en)
Prostaglandins and prostacyclins substituted by n-containing unsaturated heterocyclin derivatives,processes for their preparation and pharmaceutical compositions containing same