JPS5543007A - Prostaglandin i1-family compound and its preraration - Google Patents

Prostaglandin i1-family compound and its preraration

Info

Publication number
JPS5543007A
JPS5543007A JP11512778A JP11512778A JPS5543007A JP S5543007 A JPS5543007 A JP S5543007A JP 11512778 A JP11512778 A JP 11512778A JP 11512778 A JP11512778 A JP 11512778A JP S5543007 A JPS5543007 A JP S5543007A
Authority
JP
Japan
Prior art keywords
compound
alkyl
preraration
prostaglandin
family compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP11512778A
Other languages
Japanese (ja)
Inventor
Masatsune Kurono
Hisao Nakai
Toshiji Kosuge
Yutaro Sasaki
Kazuaki Hama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Priority to JP11512778A priority Critical patent/JPS5543007A/en
Publication of JPS5543007A publication Critical patent/JPS5543007A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A prostaglanidin I1-family compound I[n is 0W5; R1 is -COOR7 (R7 is H, alkyl, etc.), -CH2OH, etc.; R2 is alkyl, alkenyl, etc.; R1and R2 may form -B-S-C(=O)-(B is alkylene, etc.); R3 is H, methyl, etc.; R4 is single bond, etc.; R5 is H, etc.; R6 is H or OH-protective group; Y is ethylene, etc.], its cyclodextrin clathrate compound and a non-toxic salt of the acid when R1 is -COOH.
EXAMPLE: (13E)-(6RS, 9α, 11α, 15α)-6-(Ethoxycarbonyl)-methylthio-6, 9-epoxy- 11, 15-dihydroxyprost-13-enoic acid methyl ester.
USE: Remedies for viral hepatitis, herpes, disease caused by infection with salmonellae, autoimmune disease, cancer, etc.
PROCESS: For example, the desired compound IA is prepared by reacting a compound II with R2aSH(R2a is alkyl, etc.) in the presence of an acid catalyst.
COPYRIGHT: (C)1980,JPO&Japio
JP11512778A 1978-09-21 1978-09-21 Prostaglandin i1-family compound and its preraration Pending JPS5543007A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11512778A JPS5543007A (en) 1978-09-21 1978-09-21 Prostaglandin i1-family compound and its preraration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11512778A JPS5543007A (en) 1978-09-21 1978-09-21 Prostaglandin i1-family compound and its preraration

Publications (1)

Publication Number Publication Date
JPS5543007A true JPS5543007A (en) 1980-03-26

Family

ID=14654928

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11512778A Pending JPS5543007A (en) 1978-09-21 1978-09-21 Prostaglandin i1-family compound and its preraration

Country Status (1)

Country Link
JP (1) JPS5543007A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0625596A (en) * 1985-08-19 1994-02-01 Ppg Ind Inc Liquid crosslinkable composition capable of forming clear film

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0625596A (en) * 1985-08-19 1994-02-01 Ppg Ind Inc Liquid crosslinkable composition capable of forming clear film

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