ZA804057B - Anti-psychotic phthalimidine derivatives - Google Patents

Anti-psychotic phthalimidine derivatives

Info

Publication number
ZA804057B
ZA804057B ZA00804057A ZA804057A ZA804057B ZA 804057 B ZA804057 B ZA 804057B ZA 00804057 A ZA00804057 A ZA 00804057A ZA 804057 A ZA804057 A ZA 804057A ZA 804057 B ZA804057 B ZA 804057B
Authority
ZA
South Africa
Prior art keywords
psychotic
phthalimidine
derivatives
phthalimidine derivatives
psychotic phthalimidine
Prior art date
Application number
ZA00804057A
Other languages
English (en)
Inventor
K Bergtsson
S Thorberg
S Oegren
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of ZA804057B publication Critical patent/ZA804057B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA00804057A 1979-08-27 1980-07-04 Anti-psychotic phthalimidine derivatives ZA804057B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7907121A SE7907121L (sv) 1979-08-27 1979-08-27 Ftalimidinderivat

Publications (1)

Publication Number Publication Date
ZA804057B true ZA804057B (en) 1981-07-29

Family

ID=20338703

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00804057A ZA804057B (en) 1979-08-27 1980-07-04 Anti-psychotic phthalimidine derivatives

Country Status (12)

Country Link
US (1) US4289781A (xx)
EP (1) EP0026749A1 (xx)
JP (1) JPS5634679A (xx)
AU (1) AU6151380A (xx)
DK (1) DK365280A (xx)
ES (6) ES494508A0 (xx)
FI (1) FI802686A (xx)
IL (1) IL60478A0 (xx)
NO (1) NO802215L (xx)
SE (1) SE7907121L (xx)
SU (1) SU969164A3 (xx)
ZA (1) ZA804057B (xx)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1169078A (en) * 1980-12-29 1984-06-12 Michael J. Fifolt Method for the preparation of fluorophthalamic compounds
ZA83508B (en) * 1982-01-27 1983-10-26 Britax Wingard Ltd Ferrule attachment
EP0093488A3 (en) * 1982-03-18 1984-05-23 Beecham Group Plc Nortropyl benzopyrrolinone compounds, process for their preparation and pharmaceutical compositions containing them
US4495194A (en) * 1982-11-12 1985-01-22 Mead Johnson & Company Antihypertensive isoindole derivatives
US4600758A (en) * 1982-11-12 1986-07-15 Mead Johnson & Company Isoindole derivatives
US4505911A (en) * 1983-10-13 1985-03-19 Mead Johnson & Company Isoindole diuretic derivatives, compositions and use
US4585773A (en) * 1984-07-11 1986-04-29 Bristol-Myers Company Isoindolinyl-alkyl-piperazines
JPS6169773A (ja) * 1984-09-14 1986-04-10 Takeda Chem Ind Ltd イソインドリノン誘導体
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
EP0351283A1 (fr) * 1988-07-12 1990-01-17 Synthelabo Dérivés de [(pipéridinyl-4) méthyl]-2 dihydro-2,3 1H-isoindole et tétrahydro-2,3,4,5 1H-benzazépines, leur préparation et leur application en thérapeutique
US5070094A (en) * 1989-09-05 1991-12-03 G. D. Searle & Co. N-benzyltropaneamides
US5028616A (en) * 1989-09-05 1991-07-02 G. D. Searle & Co. N-benzylpiperidine amides
US5210090A (en) * 1989-09-05 1993-05-11 G. D. Searle & Co. Substituted N-benzylpiperidine amides and cardiac regulatory compositions thereof
US4992446A (en) * 1989-09-05 1991-02-12 G. D. Searle & Co. Tricyclic quinolizine amides
US5053413A (en) * 1989-09-05 1991-10-01 G. D. Searle & Co. N-benzylpiperidineisoindolinones
US5098915A (en) * 1989-09-05 1992-03-24 G. D. Searle & Co. Substituted N-benzylpiperidine amides
ZA908641B (en) * 1989-10-27 1992-06-24 Du Pont (n-phthalimidoalkyl)piperidines
US5356906A (en) * 1989-10-27 1994-10-18 The Du Pont Merck Pharmaceutical Company (N-phthalimidoalkyl) piperidines useful as treatments for psychosis
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
US5162341A (en) * 1991-02-22 1992-11-10 Du Pont Merck Pharmaceutical Company Use of sigma receptor antagonists for treatment of amphetamine abuse
US5739135A (en) * 1993-09-03 1998-04-14 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5567718A (en) * 1994-08-11 1996-10-22 Hoechst Marion Roussel Inc. 2,3-dihydro-1h-isoindole derivatives and their use as serotonin reuptake inhibitors
US5827875A (en) * 1996-05-10 1998-10-27 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5885983A (en) * 1996-05-10 1999-03-23 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5883109A (en) * 1996-07-24 1999-03-16 Bristol-Myers Squibb Company Method for lowering serum lipid levels employing an MTP inhibitor in combination with another cholesterol lowering drug
US5760246A (en) 1996-12-17 1998-06-02 Biller; Scott A. Conformationally restricted aromatic inhibitors of microsomal triglyceride transfer protein and method
WO2000000472A1 (en) 1998-06-30 2000-01-06 Du Pont Pharmaceuticals Company 5-ht7 receptor antagonists
FI20021421A0 (fi) * 2002-07-30 2002-07-30 Orion Corp Fermion Valmistusmenetelmä
US6881815B2 (en) * 2002-09-25 2005-04-19 General Electric Company Method for the preparation poly(etherimide)s
TW200918062A (en) * 2007-09-12 2009-05-01 Wyeth Corp Azacyclylisoquinolinone and-isoindolinone derivatives as histamine-3 antagonists
US8278302B2 (en) 2009-04-08 2012-10-02 Boehringer Ingelheim International Gmbh Substituted piperidines as CCR3 antagonists
UA109290C2 (uk) 2010-10-07 2015-08-10 Спільні кристали і солі інгібіторів ccr3
US8680280B2 (en) 2012-04-02 2014-03-25 Boehringer Ingelheim International Gmbh Process for the manufacturing of CRR inhibitors
US10213421B2 (en) 2012-04-04 2019-02-26 Alkahest, Inc. Pharmaceutical formulations comprising CCR3 antagonists

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE333734B (xx) 1969-04-23 1971-03-29 Kabi Ab
IL34317A0 (en) 1969-04-23 1970-06-17 Kabi Ab Substituted acetamides,their preparation and pharmaceutical compositions containing them
GB1486104A (en) 1975-01-23 1977-09-21 Wyeth John & Brother Ltd Phthalimidopiperidine derivatives
US4053615A (en) * 1972-10-21 1977-10-11 John Wyeth & Brother Limited Phthalimidopiperidines and anti-convulsant compositions thereof
GB1425578A (en) * 1972-10-21 1976-02-18 Wyeth John & Brother Ltd Piperidine derivatives
US4000287A (en) * 1974-12-16 1976-12-28 Ciba-Geigy Corporation Isoindolinopiperidines

Also Published As

Publication number Publication date
ES494505A0 (es) 1981-08-01
EP0026749A1 (en) 1981-04-08
ES8104275A1 (es) 1981-04-01
ES8106722A1 (es) 1981-08-01
SE7907121L (sv) 1981-02-28
IL60478A0 (en) 1980-09-16
JPS5634679A (en) 1981-04-06
ES494507A0 (es) 1981-04-01
ES8103744A1 (es) 1981-03-16
ES8106723A1 (es) 1981-08-01
NO802215L (no) 1981-03-02
ES8106721A1 (es) 1981-08-01
FI802686A (fi) 1981-02-28
ES494504A0 (es) 1981-03-16
AU6151380A (en) 1981-03-05
ES494506A0 (es) 1981-08-01
DK365280A (da) 1981-02-28
ES494508A0 (es) 1981-08-01
ES494502A0 (es) 1981-03-16
US4289781A (en) 1981-09-15
ES8103743A1 (es) 1981-03-16
SU969164A3 (ru) 1982-10-23

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