ZA801659B - Controlled release compositions - Google Patents

Controlled release compositions

Info

Publication number
ZA801659B
ZA801659B ZA00801659A ZA801659A ZA801659B ZA 801659 B ZA801659 B ZA 801659B ZA 00801659 A ZA00801659 A ZA 00801659A ZA 801659 A ZA801659 A ZA 801659A ZA 801659 B ZA801659 B ZA 801659B
Authority
ZA
South Africa
Prior art keywords
controlled release
release compositions
prostaglandin
residues
linked
Prior art date
Application number
ZA00801659A
Other languages
English (en)
Inventor
N Graham
M Embrey
Original Assignee
N Graham
M Embrey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by N Graham, M Embrey filed Critical N Graham
Publication of ZA801659B publication Critical patent/ZA801659B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/4833—Polyethers containing oxyethylene units
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/65—Low-molecular-weight compounds having active hydrogen with high-molecular-weight compounds having active hydrogen
    • C08G18/66—Compounds of groups C08G18/42, C08G18/48, or C08G18/52
    • C08G18/6666—Compounds of group C08G18/48 or C08G18/52
    • C08G18/667—Compounds of group C08G18/48 or C08G18/52 with compounds of group C08G18/32 or polyamines of C08G18/38
    • C08G18/6674—Compounds of group C08G18/48 or C08G18/52 with compounds of group C08G18/32 or polyamines of C08G18/38 with compounds of group C08G18/3203
    • C08G18/6677—Compounds of group C08G18/48 or C08G18/52 with compounds of group C08G18/32 or polyamines of C08G18/38 with compounds of group C08G18/3203 having at least three hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2210/00—Compositions for preparing hydrogels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2250/00—Compositions for preparing crystalline polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Lubricants (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Structures Of Non-Positive Displacement Pumps (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Fluid-Damping Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA00801659A 1979-03-21 1980-03-21 Controlled release compositions ZA801659B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7909853 1979-03-21

Publications (1)

Publication Number Publication Date
ZA801659B true ZA801659B (en) 1981-10-28

Family

ID=10504015

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA00801654A ZA801654B (en) 1979-03-21 1980-03-21 Controlled release compositions
ZA00801659A ZA801659B (en) 1979-03-21 1980-03-21 Controlled release compositions

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ZA00801654A ZA801654B (en) 1979-03-21 1980-03-21 Controlled release compositions

Country Status (11)

Country Link
US (2) US4931288A (xx)
EP (2) EP0016654B1 (xx)
JP (2) JPH0323529B2 (xx)
AT (2) ATE15444T1 (xx)
AU (2) AU537740B2 (xx)
DE (2) DE3071070D1 (xx)
GB (2) GB2047094B (xx)
HK (2) HK79885A (xx)
NZ (2) NZ193222A (xx)
WO (2) WO1980001984A1 (xx)
ZA (2) ZA801654B (xx)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079009A (en) * 1979-03-21 1992-01-07 National Research Development Corporation Controlled release compositions including polyethylene oxide with urethane cross-linking
NZ197543A (en) * 1980-07-02 1984-12-14 Commw Scient Ind Res Org Controlled release compositions for inclusion in intraruminal devices
US4466936A (en) * 1981-02-03 1984-08-21 Bayer Aktiengesellschaft Production of molds using gel compositions with depot action based on a polyurethane matrix and relatively high molecular weight polyols
AU558611B2 (en) * 1981-02-03 1987-02-05 Bayer Aktiengesellschaft Polyurethane gel
DK260782A (da) * 1981-06-12 1982-12-13 Nat Res Dev Hydrogeler
DE3272562D1 (en) * 1981-06-12 1986-09-18 Nat Res Dev Preparation of particulate gels
ZA831186B (en) * 1982-03-22 1983-11-30 Upjohn Ltd Gelled pge2/triacetin solutions
US4443428A (en) * 1982-06-21 1984-04-17 Euroceltique, S.A. Extended action controlled release compositions
FR2539135B1 (fr) * 1983-01-11 1986-02-28 Essilor Int Hydrogels de polyurethane et procede de fabrication
GB2135881A (en) * 1983-03-02 1984-09-12 Erba Farmitalia Method and pharmaceutical compositions for inhibiting or reducing gastrointestinal side effects of non-steroidal anti-inflammatory drugs
DE3476550D1 (en) * 1983-07-21 1989-03-09 Troponwerke Gmbh & Co Kg Thermoplastics containing antiphlogistics
GB8319766D0 (en) * 1983-07-22 1983-08-24 Graham N B Controlled release device
IL72041A (en) * 1984-06-05 1990-01-18 Elka Touitou Preparation for controlled release of iodine
US5439966A (en) * 1984-07-12 1995-08-08 National Research Development Corporation Polyethylene oxide temperature - or fluid-sensitive shape memory device
FR2582944B1 (fr) * 1985-06-11 1990-10-26 Commissariat Energie Atomique Piece en polymere, notamment en polyurethane de polyoxyethylene a gonflement anisotrope, son procede de fabrication et son utilisation comme dilatateur du col uterin
EP0347145A3 (en) * 1988-06-14 1990-10-24 University Of Utah Research Foundation Heterogeneous interpenetrating polymer networks for the controlled release of drugs
US5342624A (en) * 1989-02-16 1994-08-30 British Technology Group Ltd. Dispensing device
ATE114681T1 (de) * 1989-03-17 1994-12-15 Ono Pharmaceutical Co Biologisch abbaubare polyurethane.
US5225514A (en) * 1989-03-17 1993-07-06 Ono Pharmaceutical Co., Ltd. Azo containing polyurethanes for drug delivery to the large intestines
GB8918589D0 (en) * 1989-08-15 1989-09-27 Graham Neil B Polymeric compositions
US5833665A (en) * 1990-06-14 1998-11-10 Integra Lifesciences I, Ltd. Polyurethane-biopolymer composite
ATE104154T1 (de) * 1990-07-26 1994-04-15 Searle & Co Arzneimittel freisetzendes polymeres system.
JPH07503700A (ja) * 1991-01-03 1995-04-20 アルカーメス　コントロールド　セラピューティックス，　インコーポレイテッド カチオン生体ポリマーによるタンパク質の安定化
GB2254002B (en) * 1991-01-16 1995-03-22 Controlled Therapeutics Retrievable pessary
GB9101502D0 (en) * 1991-01-23 1991-03-06 Controlled Therapeutics Sct Controlled release compositions
US5273742A (en) * 1991-12-30 1993-12-28 Tyndale Plains-Hunter Ltd. Biomedical water soluble hydrophilic polyurethane polymers and method of use thereof
GB9313017D0 (en) * 1993-06-24 1993-08-11 Univ Strathclyde Measurement of water content
US5458879A (en) * 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
US6322815B1 (en) 1994-07-22 2001-11-27 W. Mark Saltzman Multipart drug delivery system
GB9418483D0 (en) * 1994-09-14 1994-11-02 British Tech Group Compound for use in pre-term labour
GB2295316B (en) * 1994-11-25 1997-09-10 William Leslie Porter Bolus for supplying biologically beneficial substances to ruminant animals
GB9506946D0 (en) * 1995-04-04 1995-05-24 Univ Strathclyde Microgels
US20020064546A1 (en) 1996-09-13 2002-05-30 J. Milton Harris Degradable poly(ethylene glycol) hydrogels with controlled half-life and precursors therefor
US6258351B1 (en) * 1996-11-06 2001-07-10 Shearwater Corporation Delivery of poly(ethylene glycol)-modified molecules from degradable hydrogels
DE19734538C1 (de) * 1997-07-30 1998-12-24 Jenapharm Gmbh Bioadhäsive Tablette
ES2211033T3 (es) * 1998-01-07 2004-07-01 Debio Recherche Pharmaceutique S.A. Acrilatos de polietilenglicol heterobifuncionales degradables y geles y conjugados derivados de dichos acrilatos.
US6514534B1 (en) * 1998-08-14 2003-02-04 Incept Llc Methods for forming regional tissue adherent barriers and drug delivery systems
GB9826192D0 (en) * 1998-12-01 1999-01-20 Controlled Theraputics Scotlan Oral transmucosal delivery
US7265186B2 (en) * 2001-01-19 2007-09-04 Nektar Therapeutics Al, Corporation Multi-arm block copolymers as drug delivery vehicles
TWI246524B (en) 2001-01-19 2006-01-01 Shearwater Corp Multi-arm block copolymers as drug delivery vehicles
GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
US7312301B2 (en) * 2002-12-31 2007-12-25 Nektar Therapeutics Al, Corporation Methods for the formation of hydrogels using thiosulfonate compositions and uses thereof
WO2005003821A2 (en) 2003-06-03 2005-01-13 Bay Materials Llc Phase change sensor
US20040259744A1 (en) * 2003-12-19 2004-12-23 Meidong Yang Skin and hair cleansers containing sulfur
US7282584B2 (en) * 2004-06-16 2007-10-16 Straumann Holding Ag Methylene blue
EP1609491B1 (en) * 2004-06-16 2008-02-06 Straumann Holding AG Barrier membrane
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
CA2610465A1 (en) * 2005-06-03 2006-12-14 Duramed Pharmaceuticals, Inc. Pharmaceutical compositions comprising prostanoid-receptor agonists and methods of making and using the same
ATE524509T1 (de) 2005-07-18 2011-09-15 Nektar Therapeutics Verzweigte funktionalisierte polymere unter verwendung von verzweigten polyolen als kernen
DE102005053066A1 (de) 2005-11-04 2007-05-10 Basf Ag Verwendung von Copolymeren als Solubilisatoren für in Wasser schwerlöslichen Verbindungen
WO2007065846A2 (de) * 2005-12-09 2007-06-14 Basf Se Verwendung von polyvinyllactam-polyoxyalkylen-blockcopolymeren als solubilisatoren für in wasser schwerlösliche verbindungen
GB0613333D0 (en) 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
AU2007274081B2 (en) * 2006-07-12 2012-08-02 Controlled Therapeutics (Scotland) Ltd. Drug delivery polymer with hydrochloride salt of clindamycin
GB0620685D0 (en) 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
JP2010534730A (ja) * 2007-07-26 2010-11-11 ビーエーエスエフ ソシエタス・ヨーロピア 溶液中でのグラフト重合により得られる、ポリエーテルに基づく固体形態のコポリマーの調製方法
KR20100120665A (ko) 2008-01-25 2010-11-16 더 유니버시티 오브 유타 리서치 파운데이션 일차 방출 중합체
DE102009052948B4 (de) * 2009-11-12 2013-05-29 Rkw Se Silageabdeckung
WO2012149326A1 (en) 2011-04-29 2012-11-01 Massachusetts Institute Of Technology Layer processing for pharmaceuticals
GB201110601D0 (en) 2011-06-23 2011-08-03 Controlled Therapeutics Scotland Ltd Improved bioresorbable
EP2689781A1 (en) 2012-07-26 2014-01-29 Ferring B.V. Misoprostol composition
EP2689802A1 (en) 2012-07-26 2014-01-29 Ferring B.V. Misoprostol formulation
EP2754443A1 (en) 2013-01-09 2014-07-16 Ferring B.V. Misoprostol for the induction of labour
EP2754442A1 (en) 2013-01-09 2014-07-16 Ferring B.V. Misoprostol for the induction of labour
KR20150034796A (ko) 2012-07-26 2015-04-03 훼링 비.브이. 미소프로스톨 제형
MX2015001007A (es) 2012-07-26 2015-04-09 Ferring Bv Composicion de misoprostol.
WO2015179461A1 (en) 2014-05-20 2015-11-26 Massachusetts Institute Of Technology Plasticity induced bonding
GB201916808D0 (en) 2019-11-19 2020-01-01 Ferring Bv Pharmaceutical delivery device

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES335314A1 (es) * 1966-01-06 1967-12-01 Ceskoslovenska Akademie Ved Mejoras introducidas en la preparacion de vehiculos insolubles de sustancias al menos parcialmente solubles, biologicamente activas.
US3975350A (en) * 1972-08-02 1976-08-17 Princeton Polymer Laboratories, Incorporated Hydrophilic or hydrogel carrier systems such as coatings, body implants and other articles
US3822238A (en) * 1972-08-02 1974-07-02 Princeton Polymer Lab Hydrophilic polyurethane polymers
US3953406A (en) * 1973-01-26 1976-04-27 California Institute Of Technology Water-insoluble, swellable polyurethanes
US3993551A (en) * 1973-09-10 1976-11-23 Union Carbide Corporation Process for cocrosslinking water soluble polymers and products thereof
FR2250793B1 (xx) * 1973-11-09 1978-12-29 Commissariat Energie Atomique
GB1494814A (en) * 1976-07-14 1977-12-14 Sanyo Chemical Ind Ltd Agrochemical compositions
GB1551620A (en) * 1976-12-13 1979-08-30 Ici Ltd Delivery means for biologically active agents
SE431821B (sv) * 1979-01-29 1984-03-05 Perstorp Ab Lagringsstabilt, prostaglandininnehallande medicinskt preparat

Also Published As

Publication number Publication date
EP0016654A1 (en) 1980-10-01
NZ193221A (en) 1984-08-24
US4931288A (en) 1990-06-05
GB2047093B (en) 1983-12-07
ZA801654B (en) 1981-10-28
GB2047094B (en) 1983-12-07
AU537740B2 (en) 1984-07-12
EP0016652A1 (en) 1980-10-01
EP0016654B1 (en) 1985-09-11
AU537741B2 (en) 1984-07-12
DE3071070D1 (en) 1985-10-17
GB2047093A (en) 1980-11-26
DE3071006D1 (en) 1985-09-26
JPS56500253A (xx) 1981-03-05
WO1980001985A1 (en) 1980-10-02
ATE15444T1 (de) 1985-09-15
WO1980001984A1 (en) 1980-10-02
GB2047094A (en) 1980-11-26
JPH0323530B2 (xx) 1991-03-29
JPS56500254A (xx) 1981-03-05
US4894238A (en) 1990-01-16
AU5669180A (en) 1980-09-25
NZ193222A (en) 1984-08-24
HK79785A (en) 1985-10-25
JPH0323529B2 (xx) 1991-03-29
HK79885A (en) 1985-10-25
EP0016652B1 (en) 1985-08-21
AU5669080A (en) 1980-09-25
ATE14979T1 (de) 1985-09-15

Similar Documents

Publication Publication Date Title
GB2047094B (en) Controlled release compositions
AU3618484A (en) Bioadhesive compositions and methods of treatment therewith
GB2066268B (en) Ethylene polymer composition
AU552101B2 (en) Ethylene copolymer composition
AU529762B2 (en) Olefin polymerization catalyst compositions
IL53538A (en) Highly absorbent polymeric compositions from polyhydroxy polymer graft copolymers
DE2964356D1 (en) Poly(ethylene oxide) compositions
GB2021125B (en) Biosynthetic polymeric compositions
AU551060B2 (en) Polyurethane-forming composition comprising addition polymer
AU2553377A (en) Self-extinguishing polymeric composition
AU526643B2 (en) Ethylene copolymer compositions
EP0264193A3 (en) Non-crosslinked foam
AU576604B2 (en) Fabric cleaming composition
AU538706B2 (en) Peroxide polymerisation catalyst composition
JPS5594998A (en) Oil composition containing ethylene copolymer
AU555710B2 (en) Cross-linked urea-formaldehyde polymer matrix compositions containing cyclic intermediate structures
JPS5676454A (en) High molecular composition
AU534822B2 (en) Ethylene copolymer composition
DE3361052D1 (en) Process for preparing block copolymers based on ethylene polymers and other polymers
EP0336129A3 (en) Room temperature curing, alternating isopropenyldimethylbenzylisocyanate copolymers having high isocyanate fuctionality
DE3376005D1 (en) Process for the manufacture of block copolymers on the basis of polymerisates of ethylene and other polymers
JPS5598406A (en) Semiconductive high molecular composition
JPS5598407A (en) Semiconductive high molecular composition
JPS5445353A (en) Preparation of high molecular weight polyethylene composition
PH18066A (en) Improved catalyst composition for polymerized ethylene