ZA783464B - Dihydropyridazones,their manufacture,and therapeutic agents containing dihydropyridazones - Google Patents

Dihydropyridazones,their manufacture,and therapeutic agents containing dihydropyridazones

Info

Publication number
ZA783464B
ZA783464B ZA00783464A ZA783464A ZA783464B ZA 783464 B ZA783464 B ZA 783464B ZA 00783464 A ZA00783464 A ZA 00783464A ZA 783464 A ZA783464 A ZA 783464A ZA 783464 B ZA783464 B ZA 783464B
Authority
ZA
South Africa
Prior art keywords
dihydropyridazones
manufacture
therapeutic agents
agents containing
therapeutic
Prior art date
Application number
ZA00783464A
Other languages
English (en)
Inventor
H Koenig
M Thyes
H Lehmann
R Lebkuecher
J Kunze
J Gries
D Lenke
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of ZA783464B publication Critical patent/ZA783464B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA00783464A 1977-06-18 1978-06-16 Dihydropyridazones,their manufacture,and therapeutic agents containing dihydropyridazones ZA783464B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772727481 DE2727481A1 (de) 1977-06-18 1977-06-18 Dihydropyridazone und dihydropyridazone enthaltende therapeutische mittel

Publications (1)

Publication Number Publication Date
ZA783464B true ZA783464B (en) 1979-07-25

Family

ID=6011790

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00783464A ZA783464B (en) 1977-06-18 1978-06-16 Dihydropyridazones,their manufacture,and therapeutic agents containing dihydropyridazones

Country Status (7)

Country Link
US (1) US4376771A (xx)
EP (1) EP0000113B1 (xx)
JP (1) JPS549289A (xx)
AT (2) AT361494B (xx)
CA (1) CA1108614A (xx)
DE (2) DE2727481A1 (xx)
ZA (1) ZA783464B (xx)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2854191A1 (de) * 1978-12-15 1980-07-03 Basf Ag Dihydropyridazinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende therapeutische mittel
DE2854475A1 (de) * 1978-12-16 1980-07-03 Basf Ag Neue 3,4-diaza-bicyclo eckige klammer auf 4.1.0 eckige klammer zu hepten-(2)- one-(5), verfahren zu ihrer herstellung und diese verbindungen enthaltende therapeutische mittel
GR81309B (xx) 1980-06-13 1984-12-11 Basf Ag
DE3022176A1 (de) 1980-06-13 1982-01-07 Basf Ag, 6700 Ludwigshafen Neue dihydropyridazinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende therapeutische mittel
DE3124699A1 (de) * 1981-06-24 1983-01-13 Basf Ag, 6700 Ludwigshafen Neue 2-aryl-3,4-diaza-bicyclo(4.n.0.)alken-(2)-one-(5),verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3279123D1 (de) * 1981-10-20 1988-11-24 Mitsui Toatsu Chemicals Novel pyridazinone derivatives
DE3209159A1 (de) * 1982-03-13 1983-09-15 Basf Ag, 6700 Ludwigshafen Neue 6-aryl-4,5-dihydro-3(2h)-pyridazinone, verfahren zu ihrer herstellung, diese verbindungen enthaltende therapeutische mittel und deren verwendung
DE3212304A1 (de) * 1982-04-02 1983-10-06 Nattermann A & Cie Imidazolylphenyl-tetrahydropyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3328286A1 (de) * 1982-08-07 1984-02-09 Basf Ag, 6700 Ludwigshafen Neue anilide, verfahren zu ihrer herstellung und ihre verwendung
DE3302021A1 (de) * 1983-01-22 1984-07-26 Basf Ag, 6700 Ludwigshafen 6-aryl-4,5-dihydro-3(2h)-pyridazinone, ihre herstellung und verwendung
JPH02119064A (ja) * 1988-10-28 1990-05-07 Matsushita Electric Ind Co Ltd 密閉形鉛蓄電池
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
EP1956906A4 (en) 2005-11-09 2009-12-30 Combinatorx Inc METHODS, COMPOSITIONS AND KITS FOR THE TREATMENT OF PATHOLOGIES
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
CA3089569C (en) 2007-06-04 2023-12-05 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN108676076A (zh) 2011-03-01 2018-10-19 辛纳吉制药公司 制备鸟苷酸环化酶c激动剂的方法
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
JP6499591B2 (ja) 2013-02-25 2019-04-10 シナジー ファーマシューティカルズ インコーポレイテッド 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
RS65632B1 (sr) 2013-06-05 2024-07-31 Bausch Health Ireland Ltd Ultra-prečišćeni agonisti guanilat-ciklaze c, postupak njihove pripreme i upotrebe
WO2015021358A2 (en) 2013-08-09 2015-02-12 Dominique Charmot Compounds and methods for inhibiting phosphate transport
JP2022533251A (ja) 2019-05-21 2022-07-21 アルデリックス， インコーポレイテッド 患者において血清リン酸塩を低下させるための組み合わせ

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670043C3 (de) * 1966-01-07 1975-05-22 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 3-(Aminophenyl)-pyridazon-(6)-derivaten
US3822260A (en) * 1970-10-09 1974-07-02 American Cyanamid Co 6-(cyanophenyl)-4,5-dihydro-3(2h)-pyridazinones
US3689652A (en) * 1970-10-09 1972-09-05 William Vincent Curran Method of lowering blood pressure in mammals
IL37788A0 (en) * 1970-10-09 1971-12-29 American Cyanamid Co New pyridazinone compounds,their preparation and pharmaceutical compositions containing them
US3975388A (en) * 1971-02-22 1976-08-17 Bdh Pharmaceuticals Limited Pyridazinones
DE2123246C2 (de) * 1971-05-11 1982-11-25 Basf Ag, 6700 Ludwigshafen 6-[p-(β-Phenyläthylaminoacetylamino)-phenyl]-4,5-dihydropyridazon-(3)
US3746712A (en) * 1971-06-08 1973-07-17 A Ross 6-(substituted-phenyl)-5-methyl-4,5-dihydro-3(2h)-pyridazinones
US3812256A (en) * 1971-06-08 1974-05-21 American Cyanamid Co Novel method for lowering blood pressure in mammals
BE790106A (fr) * 1971-10-14 1973-04-13 Basf Ag Dihydropyridazones, leur preparation et leurs utilisations therapeutiques
US3824271A (en) * 1972-07-20 1974-07-16 American Cyanamid Co 3-alkyl-3-(benzoyl)propionitriles
DE2304977A1 (de) * 1973-02-01 1974-08-08 Basf Ag Neue dihydropyridazinone
US4112095A (en) * 1976-10-07 1978-09-05 American Cyanamid Company 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazine hypotensive agents

Also Published As

Publication number Publication date
EP0000113A1 (de) 1979-01-10
JPS549289A (en) 1979-01-24
US4376771A (en) 1983-03-15
ATA198680A (de) 1981-01-15
EP0000113B1 (de) 1981-09-16
ATA441178A (de) 1980-08-15
CA1108614A (en) 1981-09-08
DE2727481A1 (de) 1979-01-11
AT363489B (de) 1981-08-10
DE2861089D1 (en) 1981-12-03
AT361494B (de) 1981-03-10
JPS6231708B2 (xx) 1987-07-09

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