ZA777236B - New n-(benzthiazol-2-yl)-oxamic acid derivatives and the preparation thereof - Google Patents

New n-(benzthiazol-2-yl)-oxamic acid derivatives and the preparation thereof

Info

Publication number
ZA777236B
ZA777236B ZA00777236A ZA777236A ZA777236B ZA 777236 B ZA777236 B ZA 777236B ZA 00777236 A ZA00777236 A ZA 00777236A ZA 777236 A ZA777236 A ZA 777236A ZA 777236 B ZA777236 B ZA 777236B
Authority
ZA
South Africa
Prior art keywords
benzthiazol
preparation
new
acid derivatives
oxamic acid
Prior art date
Application number
ZA00777236A
Other languages
English (en)
Inventor
O Wilhelms
M Thiel
W Winter
A Roesch
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of ZA777236B publication Critical patent/ZA777236B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA00777236A 1976-12-14 1977-12-05 New n-(benzthiazol-2-yl)-oxamic acid derivatives and the preparation thereof ZA777236B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762656468 DE2656468A1 (de) 1976-12-14 1976-12-14 N-(benzthiazol-2-yl)-oxamidsaeure- derivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA777236B true ZA777236B (en) 1978-11-29

Family

ID=5995427

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00777236A ZA777236B (en) 1976-12-14 1977-12-05 New n-(benzthiazol-2-yl)-oxamic acid derivatives and the preparation thereof

Country Status (17)

Country Link
JP (1) JPS5377058A (fr)
AR (1) AR216496A1 (fr)
AT (1) AT360523B (fr)
AU (1) AU510730B2 (fr)
BE (1) BE861794A (fr)
CS (1) CS203179B2 (fr)
DD (1) DD133329A5 (fr)
DE (1) DE2656468A1 (fr)
ES (1) ES465034A1 (fr)
FI (1) FI57594C (fr)
FR (1) FR2374317A1 (fr)
GB (1) GB1538822A (fr)
HU (1) HU175340B (fr)
NL (1) NL7713580A (fr)
SE (1) SE7714074L (fr)
SU (1) SU680647A3 (fr)
ZA (1) ZA777236B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2676775A (en) * 1949-10-24 1954-04-27 Gustav O Schulz Electric flatiron cord holder
DE3017976A1 (de) * 1980-05-10 1981-11-19 Dr. Karl Thomae Gmbh, 7950 Biberach Substituierte 2-amino-5-halogen-benzothiazole, verfahen zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4321372A (en) 1980-06-16 1982-03-23 Pfizer Inc. Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides
DE3027527A1 (de) 1980-07-19 1982-02-18 Basf Ag, 6700 Ludwigshafen Neue oxamidsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel
GB2090826B (en) * 1981-01-09 1985-06-12 Usv Pharma Corp New heterocyclic compounds useful as anti-allergie agents
DE3135250A1 (de) * 1981-09-05 1983-03-17 Basf Ag, 6700 Ludwigshafen Tricyclische thiazolyloxamate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel
US4826860A (en) * 1987-03-16 1989-05-02 Warner-Lambert Company Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents
FI91859C (fi) * 1987-06-17 1994-08-25 Eisai Co Ltd Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi
CZ2003182A3 (cs) 2000-06-21 2003-06-18 F. Hoffmann-La Roche Ag Deriváty benzothiazolu
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
JP4668265B2 (ja) 2004-05-24 2011-04-13 エフ.ホフマン−ラ ロシュ アーゲー 4−ヒドロキシ−4−メチル−ピペリジン−1−カルボン酸(4−メトキシ−7−モルホリン−4−イル−ベンゾチアゾール−2−イル)−アミド
WO2006048172A1 (fr) 2004-11-05 2006-05-11 F. Hoffmann-La Roche Ag Procede pour preparer des derives d'acide isonicotinique
KR100973609B1 (ko) 2005-03-23 2010-08-03 에프. 호프만-라 로슈 아게 mGluR2 길항제로서 아세틸렌일-피라졸로-피리미딘유도체
DE602006013493D1 (de) 2005-09-27 2010-05-20 Hoffmann La Roche Oxadiazolylpyrazolopyrimidine als mglur2-antagonisten

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4150140A (en) * 1976-12-23 1979-04-17 The Upjohn Company Benzothiazolyl oxanic acids, esters and salts

Also Published As

Publication number Publication date
NL7713580A (nl) 1978-06-16
FI57594C (fi) 1980-09-10
BE861794A (fr) 1978-06-13
FR2374317B1 (fr) 1980-11-07
HU175340B (hu) 1980-07-28
DE2656468A1 (de) 1978-06-15
ES465034A1 (es) 1978-09-01
SU680647A3 (ru) 1979-08-15
ATA890777A (de) 1980-06-15
AR216496A1 (es) 1979-12-28
GB1538822A (en) 1979-01-24
CS203179B2 (en) 1981-02-27
JPS5377058A (en) 1978-07-08
FI57594B (fi) 1980-05-30
AT360523B (de) 1981-01-12
AU510730B2 (en) 1980-07-10
DD133329A5 (de) 1978-12-27
AU3137777A (en) 1979-06-14
FI773738A (fi) 1978-06-15
FR2374317A1 (fr) 1978-07-13
SE7714074L (sv) 1978-06-15

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