ZA746594B - Isoxazole derivatives - Google Patents

Isoxazole derivatives

Info

Publication number
ZA746594B
ZA746594B ZA00746594A ZA746594A ZA746594B ZA 746594 B ZA746594 B ZA 746594B ZA 00746594 A ZA00746594 A ZA 00746594A ZA 746594 A ZA746594 A ZA 746594A ZA 746594 B ZA746594 B ZA 746594B
Authority
ZA
South Africa
Prior art keywords
isoxazole derivatives
isoxazole
derivatives
Prior art date
Application number
ZA00746594A
Other languages
English (en)
Inventor
J Saunders
W Williamson
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of ZA746594B publication Critical patent/ZA746594B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D263/57Aryl or substituted aryl radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Rheumatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA00746594A 1973-10-23 1974-10-16 Isoxazole derivatives ZA746594B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB49259/73A GB1488003A (en) 1973-10-23 1973-10-23 1,2-benzisoxazole derivatives processes for their preparation and their use as pharmaceuticals

Publications (1)

Publication Number Publication Date
ZA746594B true ZA746594B (en) 1976-06-30

Family

ID=10451720

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00746594A ZA746594B (en) 1973-10-23 1974-10-16 Isoxazole derivatives

Country Status (27)

Country Link
US (1) US3951999A (fr)
JP (2) JPS5912671B2 (fr)
AR (3) AR209755A1 (fr)
AT (1) AT341520B (fr)
AU (1) AU510909B2 (fr)
BE (1) BE821406A (fr)
BG (2) BG25991A3 (fr)
CA (1) CA1042005A (fr)
CH (2) CH605864A5 (fr)
CS (1) CS189671B2 (fr)
DD (1) DD116830A5 (fr)
DE (1) DE2450053A1 (fr)
DK (1) DK552674A (fr)
ES (3) ES431247A1 (fr)
FR (3) FR2248041B1 (fr)
GB (1) GB1488003A (fr)
HU (1) HU171613B (fr)
IE (1) IE40078B1 (fr)
IL (3) IL45880A (fr)
NL (1) NL7413848A (fr)
NZ (1) NZ175780A (fr)
PH (1) PH11022A (fr)
RO (2) RO78465A (fr)
SE (3) SE424324B (fr)
SU (3) SU604491A3 (fr)
YU (1) YU282474A (fr)
ZA (1) ZA746594B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1590587A (en) * 1977-06-28 1981-06-03 Lilly Industries Ltd Benoxaprofen
US4673746A (en) * 1978-10-06 1987-06-16 Hoechst-Roussel Pharmaceuticals, Inc. 1,2-benzisoxazoloxyacetic acids and related compounds
US4728662A (en) * 1977-11-21 1988-03-01 Hoechst-Roussel Pharmaceuticals Inc. 1,2-benzisoxazoloxyacetic acids and related compounds
NZ189705A (en) * 1978-03-01 1981-07-13 Boots Co Ltd Benzophenone-hydrazone derivatives and pesticidal compositions intermediates
US4337261A (en) * 1980-07-28 1982-06-29 Hoechst-Roussel Pharmaceuticals Inc. (1,2-Benzisoxazol)phenoxyacetic acids as diuretics
US4894461A (en) * 1981-04-27 1990-01-16 Hoechst-Roussel Pharmaceuticals, Inc. 3-(γ-chloropropyl)-6-fluoro-1,2-benzisoxazole
US4396770A (en) * 1982-04-09 1983-08-02 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-phenylpiperidines
US4609658A (en) * 1982-04-09 1986-09-02 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted) piperazines useful for reducing blood pressure
US4458075A (en) * 1982-04-09 1984-07-03 Hoechst-Roussel Pharmaceuticals Inc. 6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles
US4374245A (en) * 1982-04-09 1983-02-15 Hoechst-Roussel Pharmaceuticals Inc. 8-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
US4610988A (en) * 1982-04-09 1986-09-09 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines useful for alleviating pain
US4536578A (en) * 1982-04-09 1985-08-20 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines
US4390544A (en) * 1982-04-09 1983-06-28 Hoechst-Roussel Pharmaceuticals Inc. {1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(2-oxo-1-benzimidazolinyl}p
US4420485A (en) * 1982-09-29 1983-12-13 Hoechst-Roussel Pharmaceuticals Inc. 1'-[3-(1,2-Benzisoxazol-3-yl) proply]spiro[benzofuran-2(3H),3' or 4'-piperidines or 3'-pyrrolidines]
FR2540107B1 (fr) * 1983-01-28 1986-10-17 Inst Rech Chim Biolog Nouveaux derives d'halogenobenzophenone-oxime, utilisation en therapeutique et procede de preparation
FI92189C (fi) * 1986-03-17 1994-10-10 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisen difenyylimetaanijohdannaisen valmistamiseksi
US4898874A (en) * 1986-09-15 1990-02-06 A. H. Robins Company, Inc. Acetic acid derivatives of 3-aryl-2,1-benzisoxazole and esters and amides thereof
JPH037961U (fr) * 1989-06-14 1991-01-25
US5114960A (en) * 1989-07-20 1992-05-19 Hoffmann-La Roche Inc. Substituted isoxazole derivatives
MX2008010187A (es) * 2006-02-10 2008-10-31 Summit Corp Plc Tratamiento de distrofia muscular de duchenne.
CA2847293C (fr) * 2011-09-16 2017-03-28 Richard Frederic Labaudiniere Formes solides d'un inhibiteur de la dissociation de derives de transthyretine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH1093669A4 (fr) * 1969-07-17 1971-02-15
FR2093173A5 (en) * 1970-06-04 1972-01-28 Gen Mills Inc Substituted 2-hydroxybenzophenoximes for - copper extraction

Also Published As

Publication number Publication date
JPS57154174A (en) 1982-09-22
SU604491A3 (ru) 1978-04-25
RO74031A (fr) 1982-02-01
AR221321A1 (es) 1981-01-30
SU608476A3 (ru) 1978-05-25
ATA852374A (de) 1977-06-15
SE7413237L (fr) 1975-04-24
SE435713B (sv) 1984-10-15
AU7454774A (en) 1976-04-29
CH595360A5 (fr) 1978-02-15
JPS636066B2 (fr) 1988-02-08
NZ175780A (en) 1978-04-03
FR2361359A1 (fr) 1978-03-10
CS189671B2 (en) 1979-04-30
BE821406A (fr) 1975-04-23
HU171613B (hu) 1978-02-28
AU510909B2 (en) 1980-07-17
DK552674A (fr) 1975-06-16
IL52179A0 (en) 1977-07-31
JPS5077364A (fr) 1975-06-24
JPS5912671B2 (ja) 1984-03-24
AT341520B (de) 1978-02-10
GB1488003A (en) 1977-10-05
DE2450053A1 (de) 1975-04-24
ES449654A1 (es) 1977-07-01
AU2880177A (en) 1979-03-15
DD116830A5 (fr) 1975-12-12
AR213086A1 (es) 1978-12-15
ES449655A1 (es) 1977-07-01
IE40078L (en) 1975-04-23
IL45880A0 (en) 1974-12-31
US3951999A (en) 1976-04-20
SE7710599L (sv) 1977-09-21
YU282474A (en) 1982-02-28
SU795459A3 (ru) 1981-01-07
IL52180A0 (en) 1977-07-31
FR2248041B1 (fr) 1978-09-08
FR2361328A1 (fr) 1978-03-10
FR2248041A1 (fr) 1975-05-16
CA1042005A (fr) 1978-11-07
PH11022A (en) 1977-10-25
IL45880A (en) 1979-09-30
BG25991A3 (fr) 1979-01-12
BG26531A4 (fr) 1979-04-12
ES431247A1 (es) 1977-02-16
AR209755A1 (es) 1977-05-31
FR2361359B1 (fr) 1979-07-20
NL7413848A (nl) 1975-04-25
IE40078B1 (en) 1979-03-14
RO78465A (fr) 1982-02-26
SE424325B (sv) 1982-07-12
FR2361328B1 (fr) 1979-07-13
SE424324B (sv) 1982-07-12
CH605864A5 (fr) 1978-10-13
SE7710600L (sv) 1977-09-21

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