ZA73137B - Novel benzylpyrimidines - Google Patents

Novel benzylpyrimidines

Info

Publication number
ZA73137B
ZA73137B ZA730137A ZA73137A ZA73137B ZA 73137 B ZA73137 B ZA 73137B ZA 730137 A ZA730137 A ZA 730137A ZA 73137 A ZA73137 A ZA 73137A ZA 73137 B ZA73137 B ZA 73137B
Authority
ZA
South Africa
Prior art keywords
benzylpyrimidines
novel
novel benzylpyrimidines
Prior art date
Application number
ZA730137A
Other languages
English (en)
Inventor
E Grunberg
M Hoffer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA73137B publication Critical patent/ZA73137B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA730137A 1972-02-07 1973-01-08 Novel benzylpyrimidines ZA73137B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22429272A 1972-02-07 1972-02-07

Publications (1)

Publication Number Publication Date
ZA73137B true ZA73137B (en) 1973-09-26

Family

ID=22840026

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA730137A ZA73137B (en) 1972-02-07 1973-01-08 Novel benzylpyrimidines

Country Status (15)

Country Link
JP (1) JPS4886880A (en:Method)
KR (1) KR780000029B1 (en:Method)
AR (1) AR195821A1 (en:Method)
AT (1) AT323744B (en:Method)
AU (1) AU5191873A (en:Method)
BE (1) BE795023A (en:Method)
DD (1) DD103644A5 (en:Method)
DE (1) DE2303838C2 (en:Method)
FR (1) FR2181709B1 (en:Method)
GB (2) GB1388213A (en:Method)
IE (1) IE37259B1 (en:Method)
IL (1) IL41463A0 (en:Method)
LU (1) LU66964A1 (en:Method)
NL (1) NL7301650A (en:Method)
ZA (1) ZA73137B (en:Method)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA738760B (en) * 1972-12-21 1974-08-28 Hoffmann La Roche Process for the manufacture of benzyl pyrimidines
GB1582245A (en) * 1976-06-09 1981-01-07 Wellcome Found Benzyl cyanoacetal derivatives and their conversion to pyrimidine derivatives
LU77268A1 (en:Method) * 1977-05-05 1979-01-18
CA1084498A (en) * 1977-05-05 1980-08-26 Alexander E. Wick Benzylpyrimidines and process for the preparation thereof
DE2910510A1 (de) * 1979-03-16 1980-09-25 Heumann Ludwig & Co Gmbh 2,4-diamino-5-benzylpyrimidine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1453056A (fr) * 1964-11-12 1966-04-15 Hoffmann La Roche Procédé pour la préparation de dérivés de pyrimidine
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes
DE1620729A1 (de) * 1965-07-08 1970-08-20 Wellcome Found Verfahren zur Herstellung von substituierten Benzylpyrimidinen
US3715433A (en) * 1969-06-02 1973-02-06 Hoffmann La Roche Growth promotion in swine

Also Published As

Publication number Publication date
LU66964A1 (en:Method) 1974-09-25
GB1388213A (en) 1975-03-26
IE37259B1 (en) 1977-06-08
DE2303838C2 (de) 1982-09-23
NL7301650A (en:Method) 1973-08-09
BE795023A (fr) 1973-08-06
FR2181709B1 (en:Method) 1975-10-10
IE37259L (en) 1973-08-07
DD103644A5 (en:Method) 1974-02-05
IL41463A0 (en) 1973-04-30
AT323744B (de) 1975-07-25
AR195821A1 (es) 1973-11-09
AU5191873A (en) 1974-08-08
KR780000029B1 (en) 1978-03-10
DE2303838A1 (de) 1973-08-16
GB1388214A (en) 1975-03-26
JPS4886880A (en:Method) 1973-11-15
FR2181709A1 (en:Method) 1973-12-07

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