ZA716637B - A process for the fluorination of uracil and related pyrimidines - Google Patents
A process for the fluorination of uracil and related pyrimidinesInfo
- Publication number
- ZA716637B ZA716637B ZA716637A ZA716637A ZA716637B ZA 716637 B ZA716637 B ZA 716637B ZA 716637 A ZA716637 A ZA 716637A ZA 716637 A ZA716637 A ZA 716637A ZA 716637 B ZA716637 B ZA 716637B
- Authority
- ZA
- South Africa
- Prior art keywords
- fluorination
- pyrimidines
- uracil
- related pyrimidines
- Prior art date
Links
- ISAKRJDGNUQOIC-UHFFFAOYSA-N Uracil Chemical compound O=C1C=CNC(=O)N1 ISAKRJDGNUQOIC-UHFFFAOYSA-N 0.000 title 2
- 238000003682 fluorination reaction Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000003230 pyrimidines Chemical class 0.000 title 1
- 229940035893 uracil Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7823570A | 1970-10-05 | 1970-10-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA716637B true ZA716637B (en) | 1972-12-27 |
Family
ID=22142782
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA716637A ZA716637B (en) | 1970-10-05 | 1971-10-04 | A process for the fluorination of uracil and related pyrimidines |
Country Status (16)
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2401619C2 (de) * | 1974-01-14 | 1986-04-03 | Kailash Kumar Prof. Dr. 2359 Lentföhrden Gauri | Fungistatisch wirksame Uracilderivate und Verfahren zu ihrer Herstellung |
JPS52133994A (en) * | 1976-04-29 | 1977-11-09 | Daikin Ind Ltd | Method of fluorination |
JPS5640813A (en) * | 1979-09-10 | 1981-04-17 | Minolta Camera Co Ltd | Electric power unit for flash emitting device |
JPS58140098A (ja) * | 1982-01-27 | 1983-08-19 | Daikin Ind Ltd | ウリジン誘導体の製法およびウリジン誘導体 |
JPS60190769A (ja) * | 1984-03-09 | 1985-09-28 | Sagami Chem Res Center | 5−フルオロウラシルの製造方法 |
JPH055677Y2 (enrdf_load_stackoverflow) * | 1985-05-22 | 1993-02-15 |
-
1971
- 1971-10-04 CH CH1442371A patent/CH567002A5/xx not_active IP Right Cessation
- 1971-10-04 DE DE19712149504 patent/DE2149504A1/de not_active Ceased
- 1971-10-04 DK DK481171AA patent/DK128496B/da unknown
- 1971-10-04 JP JP7720771A patent/JPS5432790B1/ja active Pending
- 1971-10-04 NL NL7113583A patent/NL7113583A/xx active Search and Examination
- 1971-10-04 CA CA124,296A patent/CA1009657A/en not_active Expired
- 1971-10-04 GB GB4610071A patent/GB1362839A/en not_active Expired
- 1971-10-04 AR AR238287A patent/AR199762A1/es active
- 1971-10-04 ZA ZA716637A patent/ZA716637B/xx unknown
- 1971-10-04 BE BE773446A patent/BE773446A/xx unknown
- 1971-10-04 NO NO3634/71A patent/NO135985C/no unknown
- 1971-10-04 FR FR7135619A patent/FR2110952A5/fr not_active Expired
- 1971-10-04 SE SE7112537A patent/SE408418B/xx unknown
- 1971-10-05 AU AU34181/71A patent/AU454408B2/en not_active Expired
- 1971-10-06 IL IL37855A patent/IL37855A/xx unknown
-
1978
- 1978-02-16 JP JP1710078A patent/JPS53147081A/ja active Pending
- 1978-02-16 JP JP1710178A patent/JPS53147082A/ja active Granted
- 1978-02-16 JP JP53017099A patent/JPS58421B2/ja not_active Expired
- 1978-03-23 HK HK156/78A patent/HK15678A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
IL37855A (en) | 1974-12-31 |
AU3418171A (en) | 1973-04-12 |
DE2149504A1 (de) | 1972-07-06 |
SE408418B (sv) | 1979-06-11 |
CA1009657A (en) | 1977-05-03 |
BE773446A (fr) | 1972-04-04 |
NO135985B (enrdf_load_stackoverflow) | 1977-03-28 |
JPS53147080A (en) | 1978-12-21 |
JPS58421B2 (ja) | 1983-01-06 |
IL37855A0 (en) | 1971-12-29 |
CH567002A5 (enrdf_load_stackoverflow) | 1975-09-30 |
AU454408B2 (en) | 1974-10-31 |
FR2110952A5 (enrdf_load_stackoverflow) | 1972-06-02 |
JPS5432790B1 (enrdf_load_stackoverflow) | 1979-10-16 |
NL7113583A (enrdf_load_stackoverflow) | 1972-04-07 |
AR199762A1 (es) | 1974-09-30 |
JPS53147081A (en) | 1978-12-21 |
NO135985C (enrdf_load_stackoverflow) | 1977-07-06 |
GB1362839A (en) | 1974-08-07 |
HK15678A (en) | 1978-03-31 |
JPS5516583B2 (enrdf_load_stackoverflow) | 1980-05-02 |
DK128496B (da) | 1974-05-13 |
JPS53147082A (en) | 1978-12-21 |
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