ZA716637B - A process for the fluorination of uracil and related pyrimidines - Google Patents

A process for the fluorination of uracil and related pyrimidines

Info

Publication number
ZA716637B
ZA716637B ZA716637A ZA716637A ZA716637B ZA 716637 B ZA716637 B ZA 716637B ZA 716637 A ZA716637 A ZA 716637A ZA 716637 A ZA716637 A ZA 716637A ZA 716637 B ZA716637 B ZA 716637B
Authority
ZA
South Africa
Prior art keywords
fluorination
pyrimidines
uracil
related pyrimidines
Prior art date
Application number
ZA716637A
Inventor
R Hesse
D Barton
Original Assignee
Res Inst Medicine Chem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Inst Medicine Chem filed Critical Res Inst Medicine Chem
Publication of ZA716637B publication Critical patent/ZA716637B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
ZA716637A 1970-10-05 1971-10-04 A process for the fluorination of uracil and related pyrimidines ZA716637B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7823570A 1970-10-05 1970-10-05

Publications (1)

Publication Number Publication Date
ZA716637B true ZA716637B (en) 1972-12-27

Family

ID=22142782

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA716637A ZA716637B (en) 1970-10-05 1971-10-04 A process for the fluorination of uracil and related pyrimidines

Country Status (16)

Country Link
JP (4) JPS5432790B1 (en)
AR (1) AR199762A1 (en)
AU (1) AU454408B2 (en)
BE (1) BE773446A (en)
CA (1) CA1009657A (en)
CH (1) CH567002A5 (en)
DE (1) DE2149504A1 (en)
DK (1) DK128496B (en)
FR (1) FR2110952A5 (en)
GB (1) GB1362839A (en)
HK (1) HK15678A (en)
IL (1) IL37855A (en)
NL (1) NL7113583A (en)
NO (1) NO135985C (en)
SE (1) SE408418B (en)
ZA (1) ZA716637B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2401619C2 (en) * 1974-01-14 1986-04-03 Kailash Kumar Prof. Dr. 2359 Lentföhrden Gauri Fungistically active uracil derivatives and processes for their preparation
JPS52133994A (en) * 1976-04-29 1977-11-09 Daikin Ind Ltd Method of fluorination
JPS5640813A (en) * 1979-09-10 1981-04-17 Minolta Camera Co Ltd Electric power unit for flash emitting device
JPS58140098A (en) * 1982-01-27 1983-08-19 Daikin Ind Ltd Uridine derivative and its preparation
JPS59116934U (en) * 1983-01-27 1984-08-07 オリンパス光学工業株式会社 External power supply for strobe
JPS60190769A (en) * 1984-03-09 1985-09-28 Sagami Chem Res Center Production of 5-fluorouracil
JPH055677Y2 (en) * 1985-05-22 1993-02-15

Also Published As

Publication number Publication date
SE408418B (en) 1979-06-11
NL7113583A (en) 1972-04-07
AU454408B2 (en) 1974-10-31
FR2110952A5 (en) 1972-06-02
AR199762A1 (en) 1974-09-30
BE773446A (en) 1972-04-04
JPS53147081A (en) 1978-12-21
CA1009657A (en) 1977-05-03
HK15678A (en) 1978-03-31
JPS5432790B1 (en) 1979-10-16
NO135985C (en) 1977-07-06
NO135985B (en) 1977-03-28
DK128496B (en) 1974-05-13
CH567002A5 (en) 1975-09-30
IL37855A (en) 1974-12-31
GB1362839A (en) 1974-08-07
JPS53147080A (en) 1978-12-21
DE2149504A1 (en) 1972-07-06
IL37855A0 (en) 1971-12-29
AU3418171A (en) 1973-04-12
JPS53147082A (en) 1978-12-21
JPS5516583B2 (en) 1980-05-02
JPS58421B2 (en) 1983-01-06

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