ZA704191B - Benzimidazole carbamates - Google Patents

Benzimidazole carbamates

Info

Publication number
ZA704191B
ZA704191B ZA704191A ZA704191A ZA704191B ZA 704191 B ZA704191 B ZA 704191B ZA 704191 A ZA704191 A ZA 704191A ZA 704191 A ZA704191 A ZA 704191A ZA 704191 B ZA704191 B ZA 704191B
Authority
ZA
South Africa
Prior art keywords
benzimidazole carbamates
carbamates
benzimidazole
Prior art date
Application number
ZA704191A
Other languages
English (en)
Inventor
J Van Gelder
L Roevens
A Raeymaekers
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ZA704191B publication Critical patent/ZA704191B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fodder In General (AREA)
ZA704191A 1969-06-20 1970-06-19 Benzimidazole carbamates ZA704191B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83524669A 1969-06-20 1969-06-20

Publications (1)

Publication Number Publication Date
ZA704191B true ZA704191B (en) 1972-02-23

Family

ID=25269027

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA704191A ZA704191B (en) 1969-06-20 1970-06-19 Benzimidazole carbamates

Country Status (20)

Country Link
US (1) US3657267A (xx)
JP (1) JPS501272B1 (xx)
AT (2) AT307798B (xx)
BE (1) BE752089A (xx)
CH (1) CH520684A (xx)
CS (1) CS201522B2 (xx)
DK (2) DK134602B (xx)
ES (1) ES380579A1 (xx)
FI (1) FI52719C (xx)
FR (1) FR2052988B1 (xx)
GB (1) GB1307306A (xx)
HK (1) HK77976A (xx)
IL (1) IL34746A (xx)
IT (1) IT1035027B (xx)
MY (1) MY7300477A (xx)
NL (1) NL147139B (xx)
PL (1) PL72724B1 (xx)
SE (1) SE366045B (xx)
YU (1) YU34195B (xx)
ZA (1) ZA704191B (xx)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2201208A1 (de) * 1972-01-12 1973-08-02 Basf Ag Verfahren zur herstellung von aromatischen ketonen
US3929821A (en) * 1972-12-29 1975-12-30 Syntex Inc 5 (6)-Benzene ring substituted benzimidazole-2-carbamate derivatives
US4258198A (en) * 1973-05-29 1981-03-24 Smithkline Corporation 5-Cycloalkyl thio- and oxy-2-carbalkoxyaminobenzimidazoles
US3969526A (en) * 1973-05-29 1976-07-13 Smithkline Corporation Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles
DE2443297A1 (de) * 1974-09-10 1976-03-18 Hoechst Ag Anthelminthisch wirksame basisch substituierte 2-carbalkoxy-amino-benzimidazolyl-5(6)-phenylaether und -ketone sowie verfahren zu ihrer herstellung
US4026936A (en) * 1975-08-07 1977-05-31 Hoffmann-La Roche Inc. Anthelmintic pyridine and thiazole substituted benzimidazole carbamates
US4031234A (en) * 1975-08-18 1977-06-21 Syntex (U.S.A.) Inc. 1,5(6)-Disubstituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US4032536A (en) * 1976-07-22 1977-06-28 Janssen Pharmaceutica N.V. (1h-benzimidazol-2-yl)carbamates
IT1076022B (it) * 1977-04-20 1985-04-22 Montedison Spa Benzimidazolcarbammati antielmintici
JPS5535611A (en) * 1978-08-31 1980-03-12 Matsushita Electric Works Ltd Instrument with mouth washing instrument
US4299837A (en) 1979-12-05 1981-11-10 Montedison S.P.A. Anthelmintic benzimidazole-carbamates
US4435418A (en) 1982-12-13 1984-03-06 Smithkline Beckman Corporation 5-Phenylethenylbenzimidazoles
US4438135A (en) 1983-01-07 1984-03-20 Smithkline Beckman Corporation 1-(3,4-Bis-(3-(lower alkoxycarbonyl)-2-thioureido)-phenyl-1-phenylthylenes
WO1990010630A1 (en) * 1989-03-15 1990-09-20 Janssen Pharmaceutica N.V. [5(6)-(benzisoxa-, benzisothia- or indazol-3-yl)-1h-benzimidazol-2-yl] carbamates
NZ232785A (en) * 1989-03-15 1991-03-26 Janssen Pharmaceutica Nv 5-(1,2 benzisoxazol-, benzimidazol and benzisothiazol-3- yl)-1h-benzimadazol-2-yl carbamic acid ester derivatives preparatory processes, intermediates and anthelmintic compositions
US5256681A (en) * 1989-03-15 1993-10-26 Janssen Pharmaceutica N.V. [5(6)-(benzisoxa-,benzisothia-or indazol-3-yl)-1H-benzimidazol-2-yl]carbamates
US5278181A (en) * 1992-05-12 1994-01-11 Board Of Regents Acting On Behalf Of The University Of Michigan Soluble alkyl[5-[amino (phenyl)methyl]-1H-benzimidazol-2-yl] carbamate anthelmintics
US7893271B2 (en) * 2005-07-28 2011-02-22 Intervet International B.V. Benzimidazole carbamates and (thio) carbamates, and the synthesis and use thereof
JP5406022B2 (ja) * 2006-06-12 2014-02-05 スミス アンド ネフュー インコーポレーテッド 脛骨切除システム、方法、及び装置
EP2037914B1 (en) 2006-06-14 2013-10-23 Intervet International BV A suspension comprising benzimidazole carbamate and a polysorbate
BR112014018149B1 (pt) 2012-01-27 2020-09-29 Siegfried Rhein S.A. De C.V Composição farmacêutica de nitazoxanida
MX340272B (es) 2012-09-27 2016-06-30 Rhein Siegfried Sa De Cv Composicion sinergica de nitazoxanida y mebendazol, procesos para prepararla y el uso de dicha composicion para el tratamiento de la parasitosis humana.
EP3383852A4 (en) * 2015-11-30 2019-08-28 Children's Medical Center Corporation COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISEASES
WO2018235103A1 (en) 2017-06-22 2018-12-27 Cipla Limited Method of treatment of cancer
CN109467512B (zh) * 2018-12-18 2021-06-08 苏州开元民生科技股份有限公司 一种3,4-二氨基-二苯甲酮的合成方法
CN113979949A (zh) * 2021-12-17 2022-01-28 山东国邦药业有限公司 一种氟苯咪唑的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1111957A (en) * 1966-05-20 1968-05-01 Smith Kline French Lab Improvements in or relating to anthelmintic compositions

Also Published As

Publication number Publication date
IL34746A0 (en) 1970-08-19
BE752089A (fr) 1970-12-17
MY7300477A (en) 1973-12-31
DK134602C (xx) 1977-06-27
DE2029637B2 (de) 1976-09-23
NL147139B (nl) 1975-09-15
AT302358B (de) 1972-10-10
AT307798B (de) 1973-06-12
FR2052988A1 (xx) 1971-04-16
NL7009024A (xx) 1970-12-22
SE366045B (xx) 1974-04-08
CH520684A (fr) 1972-03-31
IL34746A (en) 1973-01-30
FR2052988B1 (xx) 1973-08-10
YU154470A (en) 1978-09-18
FI52719B (xx) 1977-08-01
GB1307306A (en) 1973-02-21
ES380579A1 (es) 1973-04-01
YU34195B (en) 1979-02-28
DE2029637A1 (de) 1971-02-18
IT1035027B (it) 1979-10-20
FI52719C (fi) 1977-11-10
HK77976A (en) 1976-12-17
DK580275A (da) 1975-12-19
CS201522B2 (en) 1980-11-28
US3657267A (en) 1972-04-18
DK134602B (da) 1976-12-06
PL72724B1 (xx) 1974-08-30
JPS501272B1 (xx) 1975-01-16

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