IT1035027B - Procedimento per la preparazione di carbammati benzimidazolici utili per la loro attivita anti elmintica e prodotto relativo - Google Patents
Procedimento per la preparazione di carbammati benzimidazolici utili per la loro attivita anti elmintica e prodotto relativoInfo
- Publication number
- IT1035027B IT1035027B IT51551/70A IT5155170A IT1035027B IT 1035027 B IT1035027 B IT 1035027B IT 51551/70 A IT51551/70 A IT 51551/70A IT 5155170 A IT5155170 A IT 5155170A IT 1035027 B IT1035027 B IT 1035027B
- Authority
- IT
- Italy
- Prior art keywords
- helmint
- benzimidazolic
- activity
- procedure
- preparation
- Prior art date
Links
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83524669A | 1969-06-20 | 1969-06-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
IT1035027B true IT1035027B (it) | 1979-10-20 |
Family
ID=25269027
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT51551/70A IT1035027B (it) | 1969-06-20 | 1970-06-18 | Procedimento per la preparazione di carbammati benzimidazolici utili per la loro attivita anti elmintica e prodotto relativo |
Country Status (20)
Country | Link |
---|---|
US (1) | US3657267A (it) |
JP (1) | JPS501272B1 (it) |
AT (2) | AT302358B (it) |
BE (1) | BE752089A (it) |
CH (1) | CH520684A (it) |
CS (1) | CS201522B2 (it) |
DK (2) | DK134602B (it) |
ES (1) | ES380579A1 (it) |
FI (1) | FI52719C (it) |
FR (1) | FR2052988B1 (it) |
GB (1) | GB1307306A (it) |
HK (1) | HK77976A (it) |
IL (1) | IL34746A (it) |
IT (1) | IT1035027B (it) |
MY (1) | MY7300477A (it) |
NL (1) | NL147139B (it) |
PL (1) | PL72724B1 (it) |
SE (1) | SE366045B (it) |
YU (1) | YU34195B (it) |
ZA (1) | ZA704191B (it) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2201208A1 (de) * | 1972-01-12 | 1973-08-02 | Basf Ag | Verfahren zur herstellung von aromatischen ketonen |
US3929821A (en) * | 1972-12-29 | 1975-12-30 | Syntex Inc | 5 (6)-Benzene ring substituted benzimidazole-2-carbamate derivatives |
US3969526A (en) * | 1973-05-29 | 1976-07-13 | Smithkline Corporation | Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles |
US4258198A (en) * | 1973-05-29 | 1981-03-24 | Smithkline Corporation | 5-Cycloalkyl thio- and oxy-2-carbalkoxyaminobenzimidazoles |
DE2443297A1 (de) * | 1974-09-10 | 1976-03-18 | Hoechst Ag | Anthelminthisch wirksame basisch substituierte 2-carbalkoxy-amino-benzimidazolyl-5(6)-phenylaether und -ketone sowie verfahren zu ihrer herstellung |
US4026936A (en) * | 1975-08-07 | 1977-05-31 | Hoffmann-La Roche Inc. | Anthelmintic pyridine and thiazole substituted benzimidazole carbamates |
US4031234A (en) * | 1975-08-18 | 1977-06-21 | Syntex (U.S.A.) Inc. | 1,5(6)-Disubstituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
US4032536A (en) * | 1976-07-22 | 1977-06-28 | Janssen Pharmaceutica N.V. | (1h-benzimidazol-2-yl)carbamates |
IT1076022B (it) * | 1977-04-20 | 1985-04-22 | Montedison Spa | Benzimidazolcarbammati antielmintici |
JPS5535611A (en) * | 1978-08-31 | 1980-03-12 | Matsushita Electric Works Ltd | Instrument with mouth washing instrument |
US4299837A (en) | 1979-12-05 | 1981-11-10 | Montedison S.P.A. | Anthelmintic benzimidazole-carbamates |
US4435418A (en) | 1982-12-13 | 1984-03-06 | Smithkline Beckman Corporation | 5-Phenylethenylbenzimidazoles |
US4438135A (en) | 1983-01-07 | 1984-03-20 | Smithkline Beckman Corporation | 1-(3,4-Bis-(3-(lower alkoxycarbonyl)-2-thioureido)-phenyl-1-phenylthylenes |
NZ232785A (en) * | 1989-03-15 | 1991-03-26 | Janssen Pharmaceutica Nv | 5-(1,2 benzisoxazol-, benzimidazol and benzisothiazol-3- yl)-1h-benzimadazol-2-yl carbamic acid ester derivatives preparatory processes, intermediates and anthelmintic compositions |
US5256681A (en) * | 1989-03-15 | 1993-10-26 | Janssen Pharmaceutica N.V. | [5(6)-(benzisoxa-,benzisothia-or indazol-3-yl)-1H-benzimidazol-2-yl]carbamates |
WO1990010630A1 (en) * | 1989-03-15 | 1990-09-20 | Janssen Pharmaceutica N.V. | [5(6)-(benzisoxa-, benzisothia- or indazol-3-yl)-1h-benzimidazol-2-yl] carbamates |
US5278181A (en) * | 1992-05-12 | 1994-01-11 | Board Of Regents Acting On Behalf Of The University Of Michigan | Soluble alkyl[5-[amino (phenyl)methyl]-1H-benzimidazol-2-yl] carbamate anthelmintics |
PL1913009T3 (pl) * | 2005-07-28 | 2010-10-29 | Intervet Int Bv | Nowe (tio)karbaminiany benzimidazolu o działaniu przeciwpasożytniczym i sposób ich wytwarzania |
WO2008091358A1 (en) * | 2006-06-12 | 2008-07-31 | Smith And Nephew Inc | Systems, methods and devices for tibial resection |
EP2037914B1 (en) | 2006-06-14 | 2013-10-23 | Intervet International BV | A suspension comprising benzimidazole carbamate and a polysorbate |
BR112014018149B1 (pt) | 2012-01-27 | 2020-09-29 | Siegfried Rhein S.A. De C.V | Composição farmacêutica de nitazoxanida |
US20150250765A1 (en) | 2012-09-27 | 2015-09-10 | Siegfried Rhein S.A. De C.V. | Nitazoxanide and mebendazole synergic composition, processes for the preparation thereof, and use of said composition for the treatment of human parasitosis |
CA3043549C (en) | 2015-11-30 | 2023-11-21 | Children's Medical Center Corporation | Compounds for treating proliferative diseases |
CN117899079A (zh) | 2017-06-22 | 2024-04-19 | 希普拉有限公司 | 癌症的治疗方法 |
CN109467512B (zh) * | 2018-12-18 | 2021-06-08 | 苏州开元民生科技股份有限公司 | 一种3,4-二氨基-二苯甲酮的合成方法 |
CN113979949A (zh) * | 2021-12-17 | 2022-01-28 | 山东国邦药业有限公司 | 一种氟苯咪唑的制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1111957A (en) * | 1966-05-20 | 1968-05-01 | Smith Kline French Lab | Improvements in or relating to anthelmintic compositions |
-
1969
- 1969-06-20 US US835246A patent/US3657267A/en not_active Expired - Lifetime
-
1970
- 1970-05-29 CH CH809370A patent/CH520684A/fr not_active IP Right Cessation
- 1970-05-29 GB GB2604470A patent/GB1307306A/en not_active Expired
- 1970-06-08 FR FR707021022A patent/FR2052988B1/fr not_active Expired
- 1970-06-09 ES ES380579A patent/ES380579A1/es not_active Expired
- 1970-06-16 PL PL1970141321A patent/PL72724B1/pl unknown
- 1970-06-17 SE SE08385/70A patent/SE366045B/xx unknown
- 1970-06-17 BE BE752089D patent/BE752089A/xx not_active IP Right Cessation
- 1970-06-18 FI FI701720A patent/FI52719C/fi active
- 1970-06-18 IL IL34746A patent/IL34746A/xx unknown
- 1970-06-18 YU YU1544/70A patent/YU34195B/xx unknown
- 1970-06-18 AT AT825571A patent/AT302358B/de not_active IP Right Cessation
- 1970-06-18 AT AT549770A patent/AT307798B/de not_active IP Right Cessation
- 1970-06-18 IT IT51551/70A patent/IT1035027B/it active
- 1970-06-19 ZA ZA704191A patent/ZA704191B/xx unknown
- 1970-06-19 JP JP45053435A patent/JPS501272B1/ja active Pending
- 1970-06-19 NL NL707009024A patent/NL147139B/xx not_active IP Right Cessation
- 1970-06-19 CS CS704330A patent/CS201522B2/cs unknown
- 1970-06-22 DK DK321770AA patent/DK134602B/da not_active IP Right Cessation
-
1973
- 1973-12-30 MY MY477/73A patent/MY7300477A/xx unknown
-
1975
- 1975-12-19 DK DK580275A patent/DK580275A/da unknown
-
1976
- 1976-12-09 HK HK779/76*UA patent/HK77976A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
NL147139B (nl) | 1975-09-15 |
DK580275A (da) | 1975-12-19 |
DK134602C (it) | 1977-06-27 |
GB1307306A (en) | 1973-02-21 |
NL7009024A (it) | 1970-12-22 |
AT307798B (de) | 1973-06-12 |
ES380579A1 (es) | 1973-04-01 |
FR2052988B1 (it) | 1973-08-10 |
FI52719C (fi) | 1977-11-10 |
CH520684A (fr) | 1972-03-31 |
YU154470A (en) | 1978-09-18 |
SE366045B (it) | 1974-04-08 |
JPS501272B1 (it) | 1975-01-16 |
PL72724B1 (it) | 1974-08-30 |
MY7300477A (en) | 1973-12-31 |
BE752089A (fr) | 1970-12-17 |
AT302358B (de) | 1972-10-10 |
ZA704191B (en) | 1972-02-23 |
DE2029637B2 (de) | 1976-09-23 |
IL34746A (en) | 1973-01-30 |
IL34746A0 (en) | 1970-08-19 |
DK134602B (da) | 1976-12-06 |
FI52719B (it) | 1977-08-01 |
DE2029637A1 (de) | 1971-02-18 |
US3657267A (en) | 1972-04-18 |
HK77976A (en) | 1976-12-17 |
YU34195B (en) | 1979-02-28 |
CS201522B2 (en) | 1980-11-28 |
FR2052988A1 (it) | 1971-04-16 |
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