ZA202212301B - Detecting a chromosome conformation as marker for fibrosis, e.g. scleroderma - Google Patents

Detecting a chromosome conformation as marker for fibrosis, e.g. scleroderma

Info

Publication number
ZA202212301B
ZA202212301B ZA2022/12301A ZA202212301A ZA202212301B ZA 202212301 B ZA202212301 B ZA 202212301B ZA 2022/12301 A ZA2022/12301 A ZA 2022/12301A ZA 202212301 A ZA202212301 A ZA 202212301A ZA 202212301 B ZA202212301 B ZA 202212301B
Authority
ZA
South Africa
Prior art keywords
scleroderma
fibrosis
marker
detecting
chromosome conformation
Prior art date
Application number
ZA2022/12301A
Other languages
English (en)
Inventor
Aroul Selvam Ramadass
Ewan Hunter
Alexandre Akoulitchev
Original Assignee
Oxford BioDynamics PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford BioDynamics PLC filed Critical Oxford BioDynamics PLC
Publication of ZA202212301B publication Critical patent/ZA202212301B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA2022/12301A 2020-06-02 2022-11-10 Detecting a chromosome conformation as marker for fibrosis, e.g. scleroderma ZA202212301B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB2008269.9A GB202008269D0 (en) 2020-06-02 2020-06-02 Detecting a chromosome marker
PCT/GB2021/051356 WO2021245409A1 (en) 2020-06-02 2021-06-02 Detecting a chromosome conformation as marker for fibrosis, e.g. scleroderma

Publications (1)

Publication Number Publication Date
ZA202212301B true ZA202212301B (en) 2023-07-26

Family

ID=71526294

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2022/12301A ZA202212301B (en) 2020-06-02 2022-11-10 Detecting a chromosome conformation as marker for fibrosis, e.g. scleroderma

Country Status (12)

Country Link
US (1) US20230193390A1 (enExample)
EP (1) EP4158066A1 (enExample)
JP (1) JP2023528621A (enExample)
KR (1) KR20230019939A (enExample)
CN (1) CN116507740A (enExample)
AU (1) AU2021283746B2 (enExample)
CA (1) CA3178914A1 (enExample)
GB (2) GB202008269D0 (enExample)
IL (1) IL298266A (enExample)
TW (1) TW202210635A (enExample)
WO (1) WO2021245409A1 (enExample)
ZA (1) ZA202212301B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202314402D0 (en) * 2023-09-20 2023-11-01 Oxford BioDynamics PLC Chromosome detection assay

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003259877A (ja) * 2002-03-11 2003-09-16 Sumitomo Pharmaceut Co Ltd 肝線維症疾患マーカーおよびその利用
US7468249B2 (en) * 2004-05-05 2008-12-23 Biocept, Inc. Detection of chromosomal disorders
WO2005111241A2 (en) * 2004-05-07 2005-11-24 Applera Corporation Genetic polymorphisms associated with liver fibrosis methods of detection and uses thereof
AU2006264564B2 (en) * 2005-07-04 2012-04-19 Erasmus University Medical Center Chromosome conformation capture-on-chip (4c) assay
CN108624668B (zh) * 2013-02-01 2022-12-02 加利福尼亚大学董事会 用于基因组组装及单体型定相的方法
JP2018527016A (ja) * 2015-06-24 2018-09-20 オックスフォード バイオダイナミックス リミテッド 染色体相互作用の検出
ES2971286T3 (es) * 2016-12-01 2024-06-04 Oxford BioDynamics PLC Aplicación de interacciones cromosómicas epigenéticas en diagnóstico de cáncer
CN111511930B (zh) * 2017-11-03 2024-11-22 牛津生物动力有限责任公司 通过染色体相互作用遗传调节免疫响应
US20230054595A1 (en) * 2019-12-18 2023-02-23 The Children's Hospital Of Philadelphia Novel druggable targets for the treatment of inflammatory diseases such as systemic lupus erythematosus (sle) and methods for diagnosis and treatment using the same

Also Published As

Publication number Publication date
GB202219352D0 (en) 2023-02-01
AU2021283746B2 (en) 2023-06-15
WO2021245409A1 (en) 2021-12-09
GB202008269D0 (en) 2020-07-15
US20230193390A1 (en) 2023-06-22
CA3178914A1 (en) 2021-12-09
CN116507740A (zh) 2023-07-28
GB2611903B (en) 2025-08-06
TW202210635A (zh) 2022-03-16
AU2021283746A1 (en) 2022-12-22
EP4158066A1 (en) 2023-04-05
IL298266A (en) 2023-01-01
GB2611903A (en) 2023-04-19
JP2023528621A (ja) 2023-07-05
KR20230019939A (ko) 2023-02-09

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