KR20230019939A - 섬유증, 예를 들어 경피증에 대한 마커로서의 염색체 형태 검출 - Google Patents

섬유증, 예를 들어 경피증에 대한 마커로서의 염색체 형태 검출 Download PDF

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Publication number
KR20230019939A
KR20230019939A KR1020237000132A KR20237000132A KR20230019939A KR 20230019939 A KR20230019939 A KR 20230019939A KR 1020237000132 A KR1020237000132 A KR 1020237000132A KR 20237000132 A KR20237000132 A KR 20237000132A KR 20230019939 A KR20230019939 A KR 20230019939A
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KR
South Korea
Prior art keywords
chromosomal
tables
interactions
markers
fibrosis
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Pending
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KR1020237000132A
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English (en)
Korean (ko)
Inventor
아룰 셀밤 라마다스
이완 헌터
알렉산드레 아쿨리체프
Original Assignee
옥스포드 바이오다이나믹스 피엘씨
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Publication of KR20230019939A publication Critical patent/KR20230019939A/ko
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020237000132A 2020-06-02 2021-06-02 섬유증, 예를 들어 경피증에 대한 마커로서의 염색체 형태 검출 Pending KR20230019939A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2008269.9 2020-06-02
GBGB2008269.9A GB202008269D0 (en) 2020-06-02 2020-06-02 Detecting a chromosome marker
PCT/GB2021/051356 WO2021245409A1 (en) 2020-06-02 2021-06-02 Detecting a chromosome conformation as marker for fibrosis, e.g. scleroderma

Publications (1)

Publication Number Publication Date
KR20230019939A true KR20230019939A (ko) 2023-02-09

Family

ID=71526294

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237000132A Pending KR20230019939A (ko) 2020-06-02 2021-06-02 섬유증, 예를 들어 경피증에 대한 마커로서의 염색체 형태 검출

Country Status (12)

Country Link
US (1) US20230193390A1 (enExample)
EP (1) EP4158066A1 (enExample)
JP (1) JP2023528621A (enExample)
KR (1) KR20230019939A (enExample)
CN (1) CN116507740A (enExample)
AU (1) AU2021283746B2 (enExample)
CA (1) CA3178914A1 (enExample)
GB (2) GB202008269D0 (enExample)
IL (1) IL298266A (enExample)
TW (1) TW202210635A (enExample)
WO (1) WO2021245409A1 (enExample)
ZA (1) ZA202212301B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202314402D0 (en) * 2023-09-20 2023-11-01 Oxford BioDynamics PLC Chromosome detection assay

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003259877A (ja) * 2002-03-11 2003-09-16 Sumitomo Pharmaceut Co Ltd 肝線維症疾患マーカーおよびその利用
US7468249B2 (en) * 2004-05-05 2008-12-23 Biocept, Inc. Detection of chromosomal disorders
WO2005111241A2 (en) * 2004-05-07 2005-11-24 Applera Corporation Genetic polymorphisms associated with liver fibrosis methods of detection and uses thereof
AU2006264564B2 (en) * 2005-07-04 2012-04-19 Erasmus University Medical Center Chromosome conformation capture-on-chip (4c) assay
CN108624668B (zh) * 2013-02-01 2022-12-02 加利福尼亚大学董事会 用于基因组组装及单体型定相的方法
JP2018527016A (ja) * 2015-06-24 2018-09-20 オックスフォード バイオダイナミックス リミテッド 染色体相互作用の検出
ES2971286T3 (es) * 2016-12-01 2024-06-04 Oxford BioDynamics PLC Aplicación de interacciones cromosómicas epigenéticas en diagnóstico de cáncer
CN111511930B (zh) * 2017-11-03 2024-11-22 牛津生物动力有限责任公司 通过染色体相互作用遗传调节免疫响应
US20230054595A1 (en) * 2019-12-18 2023-02-23 The Children's Hospital Of Philadelphia Novel druggable targets for the treatment of inflammatory diseases such as systemic lupus erythematosus (sle) and methods for diagnosis and treatment using the same

Also Published As

Publication number Publication date
GB202219352D0 (en) 2023-02-01
AU2021283746B2 (en) 2023-06-15
WO2021245409A1 (en) 2021-12-09
GB202008269D0 (en) 2020-07-15
US20230193390A1 (en) 2023-06-22
ZA202212301B (en) 2023-07-26
CA3178914A1 (en) 2021-12-09
CN116507740A (zh) 2023-07-28
GB2611903B (en) 2025-08-06
TW202210635A (zh) 2022-03-16
AU2021283746A1 (en) 2022-12-22
EP4158066A1 (en) 2023-04-05
IL298266A (en) 2023-01-01
GB2611903A (en) 2023-04-19
JP2023528621A (ja) 2023-07-05

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