CA3178914A1 - Detecting a chromosome conformation as marker for fibrosis, e.g. scleroderma - Google Patents

Detecting a chromosome conformation as marker for fibrosis, e.g. scleroderma Download PDF

Info

Publication number
CA3178914A1
CA3178914A1 CA3178914A CA3178914A CA3178914A1 CA 3178914 A1 CA3178914 A1 CA 3178914A1 CA 3178914 A CA3178914 A CA 3178914A CA 3178914 A CA3178914 A CA 3178914A CA 3178914 A1 CA3178914 A1 CA 3178914A1
Authority
CA
Canada
Prior art keywords
orf1
chromosome
markers
ssc
obd168
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3178914A
Other languages
English (en)
French (fr)
Inventor
Aroul Selvam Ramadass
Ewan HUNTER
Alexandre Akoulitchev
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford Biodynamics PLC
Original Assignee
Oxford Biodynamics PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford Biodynamics PLC filed Critical Oxford Biodynamics PLC
Publication of CA3178914A1 publication Critical patent/CA3178914A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA3178914A 2020-06-02 2021-06-02 Detecting a chromosome conformation as marker for fibrosis, e.g. scleroderma Pending CA3178914A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2008269.9 2020-06-02
GBGB2008269.9A GB202008269D0 (en) 2020-06-02 2020-06-02 Detecting a chromosome marker
PCT/GB2021/051356 WO2021245409A1 (en) 2020-06-02 2021-06-02 Detecting a chromosome conformation as marker for fibrosis, e.g. scleroderma

Publications (1)

Publication Number Publication Date
CA3178914A1 true CA3178914A1 (en) 2021-12-09

Family

ID=71526294

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3178914A Pending CA3178914A1 (en) 2020-06-02 2021-06-02 Detecting a chromosome conformation as marker for fibrosis, e.g. scleroderma

Country Status (12)

Country Link
US (1) US20230193390A1 (enExample)
EP (1) EP4158066A1 (enExample)
JP (1) JP2023528621A (enExample)
KR (1) KR20230019939A (enExample)
CN (1) CN116507740A (enExample)
AU (1) AU2021283746B2 (enExample)
CA (1) CA3178914A1 (enExample)
GB (2) GB202008269D0 (enExample)
IL (1) IL298266A (enExample)
TW (1) TW202210635A (enExample)
WO (1) WO2021245409A1 (enExample)
ZA (1) ZA202212301B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202314402D0 (en) * 2023-09-20 2023-11-01 Oxford BioDynamics PLC Chromosome detection assay

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003259877A (ja) * 2002-03-11 2003-09-16 Sumitomo Pharmaceut Co Ltd 肝線維症疾患マーカーおよびその利用
US7468249B2 (en) * 2004-05-05 2008-12-23 Biocept, Inc. Detection of chromosomal disorders
WO2005111241A2 (en) * 2004-05-07 2005-11-24 Applera Corporation Genetic polymorphisms associated with liver fibrosis methods of detection and uses thereof
AU2006264564B2 (en) * 2005-07-04 2012-04-19 Erasmus University Medical Center Chromosome conformation capture-on-chip (4c) assay
CN108624668B (zh) * 2013-02-01 2022-12-02 加利福尼亚大学董事会 用于基因组组装及单体型定相的方法
JP2018527016A (ja) * 2015-06-24 2018-09-20 オックスフォード バイオダイナミックス リミテッド 染色体相互作用の検出
ES2971286T3 (es) * 2016-12-01 2024-06-04 Oxford BioDynamics PLC Aplicación de interacciones cromosómicas epigenéticas en diagnóstico de cáncer
CN111511930B (zh) * 2017-11-03 2024-11-22 牛津生物动力有限责任公司 通过染色体相互作用遗传调节免疫响应
US20230054595A1 (en) * 2019-12-18 2023-02-23 The Children's Hospital Of Philadelphia Novel druggable targets for the treatment of inflammatory diseases such as systemic lupus erythematosus (sle) and methods for diagnosis and treatment using the same

Also Published As

Publication number Publication date
GB202219352D0 (en) 2023-02-01
AU2021283746B2 (en) 2023-06-15
WO2021245409A1 (en) 2021-12-09
GB202008269D0 (en) 2020-07-15
US20230193390A1 (en) 2023-06-22
ZA202212301B (en) 2023-07-26
CN116507740A (zh) 2023-07-28
GB2611903B (en) 2025-08-06
TW202210635A (zh) 2022-03-16
AU2021283746A1 (en) 2022-12-22
EP4158066A1 (en) 2023-04-05
IL298266A (en) 2023-01-01
GB2611903A (en) 2023-04-19
JP2023528621A (ja) 2023-07-05
KR20230019939A (ko) 2023-02-09

Similar Documents

Publication Publication Date Title
JP7631400B2 (ja) 遺伝子調節
US20200407790A1 (en) Biomarker
AU2021283746B2 (en) Detecting a chromosome conformation as marker for fibrosis, e.g. scleroderma
WO2022148957A1 (en) Chromosome interactions
AU2021360263B2 (en) Disease marker
JP2025108590A (ja) 診断用染色体マーカー
US20240132959A1 (en) Chromosome Interaction Markers
CN110225981B (zh) 分型方法
WO2012078321A1 (en) Phased genome sequencing
HK40076364A (en) Diagnostic chromosome marker
WO2014071200A1 (en) Beta blocker responder status assays and related materials and methods

Legal Events

Date Code Title Description
MFA Maintenance fee for application paid

Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 4TH ANNIV.) - STANDARD

Year of fee payment: 4

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250523

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20250523

D11 Substantive examination requested

Free format text: ST27 STATUS EVENT CODE: A-1-1-D10-D11-D117 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: REQUEST FOR EXAMINATION RECEIVED

Effective date: 20250531

P11 Amendment of application requested

Free format text: ST27 STATUS EVENT CODE: A-1-1-P10-P11-P101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: AMENDMENT RECEIVED - VOLUNTARY AMENDMENT

Effective date: 20250531

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-1-1-W10-W00-W111 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CORRESPONDENT DETERMINED COMPLIANT

Effective date: 20250601

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-1-1-W10-W00-W111 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CORRESPONDENT DETERMINED COMPLIANT

Effective date: 20250603

D00 Search and/or examination requested or commenced

Free format text: ST27 STATUS EVENT CODE: A-1-1-D10-D00-D118 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: REQUEST FOR EXAMINATION REQUIREMENTS DETERMINED COMPLIANT

Effective date: 20250821

D11 Substantive examination requested

Free format text: ST27 STATUS EVENT CODE: A-1-2-D10-D11-D155 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: ALL REQUIREMENTS FOR EXAMINATION DETERMINED COMPLIANT

Effective date: 20250821

P11 Amendment of application requested

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-P102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: AMENDMENT DETERMINED COMPLIANT

Effective date: 20250821

P13 Application amended

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P13-X000 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: APPLICATION AMENDED

Effective date: 20250821

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-2-2-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT

Effective date: 20250822

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-2-2-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT

Effective date: 20260714