ZA202108950B - Oxymetazoline compositions and methods for treating ocular disorders - Google Patents

Oxymetazoline compositions and methods for treating ocular disorders

Info

Publication number
ZA202108950B
ZA202108950B ZA2021/08950A ZA202108950A ZA202108950B ZA 202108950 B ZA202108950 B ZA 202108950B ZA 2021/08950 A ZA2021/08950 A ZA 2021/08950A ZA 202108950 A ZA202108950 A ZA 202108950A ZA 202108950 B ZA202108950 B ZA 202108950B
Authority
ZA
South Africa
Prior art keywords
oxymetazoline
compositions
methods
ocular disorders
treating ocular
Prior art date
Application number
ZA2021/08950A
Other languages
English (en)
Inventor
Devries Tina
Jacobs David
Original Assignee
Rvl Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rvl Pharmaceuticals Inc filed Critical Rvl Pharmaceuticals Inc
Publication of ZA202108950B publication Critical patent/ZA202108950B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10Bag-type containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/4174Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
ZA2021/08950A 2019-05-06 2021-11-11 Oxymetazoline compositions and methods for treating ocular disorders ZA202108950B (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962844069P 2019-05-06 2019-05-06
US201962843819P 2019-05-06 2019-05-06
US16/716,014 US10799481B1 (en) 2019-05-06 2019-12-16 Compositions and methods for treating ocular disorders
US16/715,998 US10814001B1 (en) 2019-05-06 2019-12-16 Oxymetazoline compositions
PCT/US2020/031425 WO2020227260A1 (en) 2019-05-06 2020-05-05 Oxymetazoline compositions and methods for treating ocular disorders

Publications (1)

Publication Number Publication Date
ZA202108950B true ZA202108950B (en) 2023-10-25

Family

ID=72750169

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA2021/08950A ZA202108950B (en) 2019-05-06 2021-11-11 Oxymetazoline compositions and methods for treating ocular disorders
ZA2022/12328A ZA202212328B (en) 2019-05-06 2022-11-11 Oxymetazoline compositions and methods for treating ocular disorders

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA2022/12328A ZA202212328B (en) 2019-05-06 2022-11-11 Oxymetazoline compositions and methods for treating ocular disorders

Country Status (16)

Country Link
US (11) US10814001B1 (https=)
EP (1) EP3965737A1 (https=)
JP (3) JP7141420B2 (https=)
KR (3) KR102410503B1 (https=)
CN (2) CN111888326B (https=)
AU (1) AU2020268329B2 (https=)
BR (1) BR112021022404A2 (https=)
CL (1) CL2021002918A1 (https=)
CO (1) CO2021015265A2 (https=)
IL (1) IL287831A (https=)
MA (1) MA55895A (https=)
MX (1) MX2021013516A (https=)
PE (1) PE20220384A1 (https=)
SG (1) SG11202112272TA (https=)
WO (1) WO2020227260A1 (https=)
ZA (2) ZA202108950B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
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US20120225918A1 (en) * 2011-03-03 2012-09-06 Voom, Llc Compositions and Methods for Non-Surgical Treatment of Ptosis
US10814001B1 (en) * 2019-05-06 2020-10-27 Rvl Pharmaceuticals, Inc. Oxymetazoline compositions
WO2022187306A1 (en) 2021-03-03 2022-09-09 Voom, Llc Compositions and methods for treatment of blepharitis
WO2023079427A1 (en) * 2021-11-03 2023-05-11 Avaca Pharma Private Limited Ophthalmic compositions and methods thereof

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US5459133A (en) 1992-06-05 1995-10-17 Telor Ophthalmic Pharmaceuticals, Inc. Methods and products for treating presbyopia
US5888493A (en) 1996-12-05 1999-03-30 Sawaya; Assad S. Ophthalmic aqueous gel formulation and related methods
JP2002249445A (ja) 2000-12-19 2002-09-06 Ophtecs Corp 眼科用液剤組成物
US6806364B2 (en) 2002-07-29 2004-10-19 Ast Products, Inc. Ophthalmic compositions
CN101327325A (zh) * 2002-07-30 2008-12-24 奥默罗斯公司 眼科冲洗液及方法
DE10337186A1 (de) 2003-08-13 2005-03-17 Merck Patent Gmbh Wässrige Wirkstoff-Lösung
US7812049B2 (en) 2004-01-22 2010-10-12 Vicept Therapeutics, Inc. Method and therapeutic/cosmetic topical compositions for the treatment of rosacea and skin erythema using α1-adrenoceptor agonists
JP2006131628A (ja) * 2004-10-08 2006-05-25 Rohto Pharmaceut Co Ltd オキシメタゾリン含有水性組成物
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WO2008070185A2 (en) * 2006-12-06 2008-06-12 The Trustees Of Columbia University In The City Of New York Method of stabilizing human eye tissue by reaction with nitrite and related agents such as nitro compounds
WO2009061431A2 (en) 2007-11-08 2009-05-14 Aciex Therapeutics, Inc. Compositions for the treatment and prevention of eyelid swelling comprising an osmotically active ingredient and a vasoconstrictor
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UA119324C2 (uk) 2013-04-02 2019-06-10 Теміс Медікер Лімітед Композиції фармацевтично активних речовин, що містять моноетиловий ефір діетиленгліколю або інші алкільні похідні
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Also Published As

Publication number Publication date
US20230355587A1 (en) 2023-11-09
CL2021002918A1 (es) 2022-08-19
US20210386711A1 (en) 2021-12-16
US10898573B1 (en) 2021-01-26
KR20200128629A (ko) 2020-11-16
CN111888326B (zh) 2023-07-21
US11701343B2 (en) 2023-07-18
KR102663319B1 (ko) 2024-05-03
US20240033250A1 (en) 2024-02-01
US11103482B2 (en) 2021-08-31
US11541036B2 (en) 2023-01-03
US11324722B2 (en) 2022-05-10
US20210212992A1 (en) 2021-07-15
EP3965737A1 (en) 2022-03-16
SG11202112272TA (en) 2021-12-30
CN117045596A (zh) 2023-11-14
AU2020268329B2 (en) 2026-01-15
JP7141420B2 (ja) 2022-09-22
KR102859351B1 (ko) 2025-09-12
IL287831A (en) 2022-01-01
US20220273621A1 (en) 2022-09-01
CA3139443A1 (en) 2020-11-12
US20210137889A1 (en) 2021-05-13
KR102410503B1 (ko) 2022-06-17
NZ782902A (en) 2024-09-27
WO2020227260A1 (en) 2020-11-12
US20220257566A1 (en) 2022-08-18
US11311515B2 (en) 2022-04-26
JP2021191802A (ja) 2021-12-16
MX2021013516A (es) 2022-01-24
JP7705326B2 (ja) 2025-07-09
KR20240060580A (ko) 2024-05-08
BR112021022404A2 (pt) 2022-01-18
AU2020268329A1 (en) 2022-01-06
PE20220384A1 (es) 2022-03-18
US20200353083A1 (en) 2020-11-12
ZA202212328B (en) 2025-03-26
US12605363B2 (en) 2026-04-21
US20210015795A1 (en) 2021-01-21
KR20220084264A (ko) 2022-06-21
US10940138B2 (en) 2021-03-09
US10799481B1 (en) 2020-10-13
CO2021015265A2 (es) 2022-02-28
JP2020183373A (ja) 2020-11-12
US20210023222A1 (en) 2021-01-28
JP2025065198A (ja) 2025-04-17
US10814001B1 (en) 2020-10-27
CN111888326A (zh) 2020-11-06
MA55895A (fr) 2022-03-16

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