ZA202006485B - Sulforhodamine phosphoramidite dyes - Google Patents

Sulforhodamine phosphoramidite dyes

Info

Publication number
ZA202006485B
ZA202006485B ZA2020/06485A ZA202006485A ZA202006485B ZA 202006485 B ZA202006485 B ZA 202006485B ZA 2020/06485 A ZA2020/06485 A ZA 2020/06485A ZA 202006485 A ZA202006485 A ZA 202006485A ZA 202006485 B ZA202006485 B ZA 202006485B
Authority
ZA
South Africa
Prior art keywords
sulforhodamine
dyes
phosphoramidite
phosphoramidite dyes
compatible
Prior art date
Application number
ZA2020/06485A
Other languages
English (en)
Inventor
Kevin P Lund
Dmitri Sergueev
Maher N Qabar
Alexander Gall
Original Assignee
Cepheid
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cepheid filed Critical Cepheid
Publication of ZA202006485B publication Critical patent/ZA202006485B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B11/00—Diaryl- or thriarylmethane dyes
    • C09B11/04—Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
    • C09B11/10—Amino derivatives of triarylmethanes
    • C09B11/24—Phthaleins containing amino groups ; Phthalanes; Fluoranes; Phthalides; Rhodamine dyes; Phthaleins having heterocyclic aryl rings; Lactone or lactame forms of triarylmethane dyes
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B57/00—Other synthetic dyes of known constitution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA2020/06485A 2018-05-07 2020-10-19 Sulforhodamine phosphoramidite dyes ZA202006485B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862668109P 2018-05-07 2018-05-07
PCT/US2019/031188 WO2019217470A1 (en) 2018-05-07 2019-05-07 Sulforhodamine phosphoramidite dyes

Publications (1)

Publication Number Publication Date
ZA202006485B true ZA202006485B (en) 2025-07-30

Family

ID=66625340

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2020/06485A ZA202006485B (en) 2018-05-07 2020-10-19 Sulforhodamine phosphoramidite dyes

Country Status (11)

Country Link
US (2) US12071547B2 (cg-RX-API-DMAC7.html)
EP (1) EP3790931B1 (cg-RX-API-DMAC7.html)
JP (1) JP7399882B2 (cg-RX-API-DMAC7.html)
KR (1) KR102753367B1 (cg-RX-API-DMAC7.html)
CN (1) CN112533998B (cg-RX-API-DMAC7.html)
AU (1) AU2019266218B2 (cg-RX-API-DMAC7.html)
CA (1) CA3099701A1 (cg-RX-API-DMAC7.html)
ES (1) ES2967690T3 (cg-RX-API-DMAC7.html)
MX (1) MX2020011378A (cg-RX-API-DMAC7.html)
WO (1) WO2019217470A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA202006485B (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021307437A1 (en) 2020-07-16 2023-03-16 Cepheid Fluorescent dyes
CN117207137A (zh) 2022-06-10 2023-12-12 南京泉峰科技有限公司 动力工具
CN115636843B (zh) * 2022-09-27 2024-12-13 大连理工大学 一类多功能荧光染料及应用
CN115414703B (zh) * 2022-11-03 2023-01-17 百力格生物科技(上海)股份有限公司 染料修饰后的核酸探针纯化方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231191A (en) * 1987-12-24 1993-07-27 Applied Biosystems, Inc. Rhodamine phosphoramidite compounds
US5451463A (en) * 1989-08-28 1995-09-19 Clontech Laboratories, Inc. Non-nucleoside 1,3-diol reagents for labeling synthetic oligonucleotides
US6727356B1 (en) 1999-12-08 2004-04-27 Epoch Pharmaceuticals, Inc. Fluorescent quenching detection reagents and methods
US7344701B2 (en) * 2004-02-03 2008-03-18 Biosearch Technologies, Inc. Xanthene dyes
WO2007115265A2 (en) 2006-03-31 2007-10-11 Applied Biosystems Inc. Reagents useful for synthesizing rhodamine-labeled oligonucleotides
CN105412945B (zh) * 2010-04-02 2021-02-05 药物影像股份有限公司 罗丹明染料的单一同分异构结合物
WO2014058535A1 (en) 2012-08-19 2014-04-17 Michigan Technological University Lysosomal targeting probes
US9598455B2 (en) 2014-03-30 2017-03-21 Cepheid Modified thymine polynucleotide oligomers and methods
US9598456B2 (en) 2014-03-30 2017-03-21 Cepheid Modified cytosine polynucleotide oligomers and methods

Also Published As

Publication number Publication date
KR20210035079A (ko) 2021-03-31
EP3790931B1 (en) 2023-09-27
CN112533998A (zh) 2021-03-19
JP7399882B2 (ja) 2023-12-18
JP2021523268A (ja) 2021-09-02
AU2019266218B2 (en) 2024-08-15
CA3099701A1 (en) 2019-11-14
ES2967690T3 (es) 2024-05-03
KR102753367B1 (ko) 2025-01-10
US20250051577A1 (en) 2025-02-13
EP3790931A1 (en) 2021-03-17
AU2019266218A1 (en) 2021-01-07
WO2019217470A1 (en) 2019-11-14
US12071547B2 (en) 2024-08-27
CN112533998B (zh) 2023-06-20
US20240067824A1 (en) 2024-02-29
BR112020022684A2 (pt) 2021-02-17
MX2020011378A (es) 2021-02-15

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