ZA201807903B - Methods of treating circadian rhythm sleep disorders - Google Patents

Methods of treating circadian rhythm sleep disorders

Info

Publication number
ZA201807903B
ZA201807903B ZA2018/07903A ZA201807903A ZA201807903B ZA 201807903 B ZA201807903 B ZA 201807903B ZA 2018/07903 A ZA2018/07903 A ZA 2018/07903A ZA 201807903 A ZA201807903 A ZA 201807903A ZA 201807903 B ZA201807903 B ZA 201807903B
Authority
ZA
South Africa
Prior art keywords
methods
sleep disorders
circadian rhythm
rhythm sleep
treating circadian
Prior art date
Application number
ZA2018/07903A
Other languages
English (en)
Inventor
T Beuckmann Carsten
Moline Margaret
Satlin Andrew
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of ZA201807903B publication Critical patent/ZA201807903B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/501Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA2018/07903A 2016-05-12 2018-11-22 Methods of treating circadian rhythm sleep disorders ZA201807903B (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662335599P 2016-05-12 2016-05-12
US201662335611P 2016-05-12 2016-05-12
US201662413976P 2016-10-27 2016-10-27
US201662414599P 2016-10-28 2016-10-28
US201662414606P 2016-10-28 2016-10-28
PCT/US2017/032228 WO2017197160A1 (en) 2016-05-12 2017-05-11 Methods of treating circadian rhythm sleep disorders

Publications (1)

Publication Number Publication Date
ZA201807903B true ZA201807903B (en) 2021-04-28

Family

ID=58745465

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2018/07903A ZA201807903B (en) 2016-05-12 2018-11-22 Methods of treating circadian rhythm sleep disorders

Country Status (16)

Country Link
US (2) US11096941B2 (cg-RX-API-DMAC7.html)
EP (2) EP3454859B1 (cg-RX-API-DMAC7.html)
JP (2) JP6888026B2 (cg-RX-API-DMAC7.html)
KR (2) KR102511855B1 (cg-RX-API-DMAC7.html)
CN (1) CN109640998A (cg-RX-API-DMAC7.html)
AU (3) AU2017264871B2 (cg-RX-API-DMAC7.html)
CA (1) CA3022068A1 (cg-RX-API-DMAC7.html)
ES (1) ES2904625T3 (cg-RX-API-DMAC7.html)
IL (2) IL291791B2 (cg-RX-API-DMAC7.html)
MX (1) MX379318B (cg-RX-API-DMAC7.html)
MY (1) MY199382A (cg-RX-API-DMAC7.html)
RU (1) RU2763493C2 (cg-RX-API-DMAC7.html)
SG (1) SG11201809527UA (cg-RX-API-DMAC7.html)
TW (1) TWI795359B (cg-RX-API-DMAC7.html)
WO (1) WO2017197160A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201807903B (cg-RX-API-DMAC7.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201809527UA (en) * 2016-05-12 2018-11-29 Eisai R&D Man Co Ltd Methods of treating circadian rhythm sleep disorders
WO2020263253A1 (en) * 2019-06-26 2020-12-30 Moline Margaret Lemborexant for treating sleep issues
MX2021016090A (es) * 2019-06-26 2022-02-03 Eisai R&D Man Co Ltd Lemborexant para el tratamiento de problemas del sueño.
JP2022538170A (ja) * 2019-06-26 2022-08-31 エーザイ・アール・アンド・ディー・マネジメント株式会社 睡眠問題の治療のためのレンボレキサント
CA3151634A1 (en) * 2019-09-13 2021-03-18 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating insomnia
US20240010629A1 (en) * 2019-12-11 2024-01-11 Teva Czech Industries S.R.O Solid state form of lemborexant
MX2022008260A (es) * 2020-01-16 2022-08-04 Eisai R&D Man Co Ltd Sustancia farmacologica de lemborexant y composicion medicinal que la comprende.
CN111450076A (zh) * 2020-05-25 2020-07-28 安徽省逸欣铭医药科技有限公司 一种Lemborexant软胶囊组合物及其制备方法
CN114159568B (zh) * 2020-09-11 2025-08-01 北京原基华毅生物科技有限公司 Sik抑制剂在制备用于预防和/或治疗睡眠障碍的药物中的应用
JP2024527024A (ja) * 2021-07-26 2024-07-19 エーザイ・アール・アンド・ディー・マネジメント株式会社 神経変性疾患に伴う不規則睡眠・覚醒リズム障害及び概日リズム睡眠障害を治療する方法における使用のためのレンボレキサント
CN116421605B (zh) * 2022-01-04 2024-08-02 中国科学院脑科学与智能技术卓越创新中心 Isx-9在治疗衰老相关的昼夜节律幅度下降和睡眠障碍方面的应用
KR20250070087A (ko) * 2022-09-23 2025-05-20 에자이 알앤드디 매니지먼트 가부시키가이샤 신경변성 질병과 관련된 신경변성의 감소 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA06009377A (es) * 2004-02-20 2007-03-07 Lifescape Biosciences Inc Composiciones y metodos para regulacion del sueno.
WO2008026149A1 (en) * 2006-08-28 2008-03-06 Actelion Pharmaceuticals Ltd 1,4,5,6, 7,8-hexahydro-i^1s-triaza-azulene derivatives as orexin receptor antagonists
MX2013003218A (es) 2010-09-22 2013-06-28 Eisai R&D Man Co Ltd Compuestos de ciclopropano.
CA2863413A1 (en) * 2012-02-07 2013-08-15 Eolas Therapeutics, Inc. Substituted prolines / piperidines as orexin receptor antagonists
CN107810006B (zh) * 2014-10-23 2021-03-30 卫材R&D管理有限公司 用于治疗失眠的组合物
SG11201809527UA (en) * 2016-05-12 2018-11-29 Eisai R&D Man Co Ltd Methods of treating circadian rhythm sleep disorders

Also Published As

Publication number Publication date
EP3454859A1 (en) 2019-03-20
RU2763493C2 (ru) 2021-12-29
JP6888026B2 (ja) 2021-06-16
IL291791B2 (en) 2025-09-01
EP3454859B1 (en) 2021-12-01
IL291791B1 (en) 2025-05-01
US20200179382A1 (en) 2020-06-11
TWI795359B (zh) 2023-03-11
IL262803A (en) 2018-12-31
SG11201809527UA (en) 2018-11-29
IL291791A (en) 2022-06-01
AU2023203418A1 (en) 2023-06-29
MX2018013663A (es) 2019-07-18
ES2904625T3 (es) 2022-04-05
AU2017264871B2 (en) 2023-03-16
MY199382A (en) 2023-10-25
JP2021120410A (ja) 2021-08-19
WO2017197160A1 (en) 2017-11-16
IL262803B (en) 2022-05-01
JP2019518732A (ja) 2019-07-04
AU2017264871A1 (en) 2018-11-15
CN109640998A (zh) 2019-04-16
KR20190013820A (ko) 2019-02-11
KR20230043227A (ko) 2023-03-30
TW201740952A (zh) 2017-12-01
RU2018143809A3 (cg-RX-API-DMAC7.html) 2020-09-17
KR102511855B1 (ko) 2023-03-20
CA3022068A1 (en) 2017-11-16
NZ748555A (en) 2025-06-27
RU2018143809A (ru) 2020-06-15
AU2025205336A1 (en) 2025-07-31
US20210353625A1 (en) 2021-11-18
MX379318B (es) 2025-03-10
US11096941B2 (en) 2021-08-24
JP7150096B2 (ja) 2022-10-07
BR112018073037A2 (pt) 2019-02-26
EP4056180A1 (en) 2022-09-14

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