ZA201701214B - Imidazo[1,2-a]pyridine derivatives for use as inhibitors of human immunodeficiency virus replication - Google Patents

Imidazo[1,2-a]pyridine derivatives for use as inhibitors of human immunodeficiency virus replication

Info

Publication number
ZA201701214B
ZA201701214B ZA2017/01214A ZA201701214A ZA201701214B ZA 201701214 B ZA201701214 B ZA 201701214B ZA 2017/01214 A ZA2017/01214 A ZA 2017/01214A ZA 201701214 A ZA201701214 A ZA 201701214A ZA 201701214 B ZA201701214 B ZA 201701214B
Authority
ZA
South Africa
Prior art keywords
imidazo
inhibitors
immunodeficiency virus
human immunodeficiency
virus replication
Prior art date
Application number
ZA2017/01214A
Other languages
English (en)
Inventor
Narasimhulu B Naidu
Timothy P Connolly
Kyle J Eastman
Kevin Peese
Original Assignee
Viiv Healthcare Uk No 5 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54064588&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA201701214(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Viiv Healthcare Uk No 5 Ltd filed Critical Viiv Healthcare Uk No 5 Ltd
Publication of ZA201701214B publication Critical patent/ZA201701214B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA2017/01214A 2014-08-27 2017-02-17 Imidazo[1,2-a]pyridine derivatives for use as inhibitors of human immunodeficiency virus replication ZA201701214B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462042300P 2014-08-27 2014-08-27
PCT/US2015/046648 WO2016033009A1 (en) 2014-08-27 2015-08-25 Imidazo[1,2-a]pyridine derivatives for use as inhibitors of human immunodeficiency virus replication

Publications (1)

Publication Number Publication Date
ZA201701214B true ZA201701214B (en) 2019-07-31

Family

ID=54064588

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2017/01214A ZA201701214B (en) 2014-08-27 2017-02-17 Imidazo[1,2-a]pyridine derivatives for use as inhibitors of human immunodeficiency virus replication

Country Status (13)

Country Link
US (1) US10065953B2 (enExample)
EP (1) EP3186254B1 (enExample)
JP (1) JP2017526748A (enExample)
KR (1) KR20170045308A (enExample)
CN (1) CN107001357A (enExample)
AU (1) AU2015306779B2 (enExample)
BR (1) BR112017003663A2 (enExample)
CA (1) CA2958591A1 (enExample)
CL (1) CL2017000428A1 (enExample)
IL (1) IL250561A0 (enExample)
RU (1) RU2017107715A (enExample)
WO (1) WO2016033009A1 (enExample)
ZA (1) ZA201701214B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9975906B2 (en) 2014-05-16 2018-05-22 Shionogi & Co., Ltd. Tricyclic heterocycle derivatives having HIV replication inhibitory effect
CA2987384A1 (en) 2015-05-29 2016-12-08 Shionogi & Co., Ltd. Nitrogen-containing tricyclic derivative having hiv replication inhibitory activity
CN109232562A (zh) * 2018-10-24 2019-01-18 康化（上海）新药研发有限公司 一种7-氮杂吲哚-5-氯-6-羧酸的合成方法
PT3870577T (pt) * 2018-10-24 2025-04-07 Viiv Healthcare Uk No 5 Ltd Inibidores da replicação do vírus da imunodeficiência humana
HUE059677T2 (hu) 2019-03-22 2022-12-28 Gilead Sciences Inc Áthidalt triciklusos karbamoilpiridon-vegyületek és ezek gyógyszerészeti alkalmazása
CR20220418A (es) 2020-02-24 2022-10-10 Gilead Sciences Inc Compuestos tetracíclicos para el tratamiento de infecciones por vih
JP7691494B2 (ja) 2020-09-30 2025-06-11 ギリアード サイエンシーズ， インコーポレイテッド 架橋三環式カルバモイルピリドン化合物及びその使用
LT4196479T (lt) 2021-01-19 2023-12-11 Gilead Sciences, Inc. Pakeistieji piridotriazino junginiai ir jų panaudojimo būdai
TWI843506B (zh) 2022-04-06 2024-05-21 美商基利科學股份有限公司 橋聯三環胺甲醯基吡啶酮化合物及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8338441B2 (en) * 2009-05-15 2012-12-25 Gilead Sciences, Inc. Inhibitors of human immunodeficiency virus replication
US8633200B2 (en) * 2010-09-08 2014-01-21 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
PE20141066A1 (es) * 2011-04-21 2014-09-05 Gilead Sciences Inc Compuestos de benzotiazol
US9034882B2 (en) * 2012-03-05 2015-05-19 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
PH12014500842A1 (en) * 2012-04-20 2014-06-09 Gilead Sciences Inc Benzothiazol-6-yl acetic acid derivatives and their use for treating an hiv infection
ES2623777T3 (es) * 2013-03-13 2017-07-12 VIIV Healthcare UK (No.5) Limited Inhibidores de la replicación del virus de la inmunodeficiencia humana

Also Published As

Publication number Publication date
CL2017000428A1 (es) 2017-08-18
KR20170045308A (ko) 2017-04-26
AU2015306779B2 (en) 2017-11-02
EP3186254B1 (en) 2019-03-06
RU2017107715A3 (enExample) 2019-03-04
JP2017526748A (ja) 2017-09-14
IL250561A0 (en) 2017-03-30
EP3186254A1 (en) 2017-07-05
RU2017107715A (ru) 2018-09-27
US10065953B2 (en) 2018-09-04
BR112017003663A2 (pt) 2017-11-28
US20180222901A1 (en) 2018-08-09
CA2958591A1 (en) 2016-03-03
AU2015306779A1 (en) 2017-03-16
CN107001357A (zh) 2017-08-01
WO2016033009A1 (en) 2016-03-03

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