CL2017000428A1 - Derivados de imidazo[1,2-a]piridina para su uso como inhibidores para la replica del virus de la inmunodeficiencia humana - Google Patents

Derivados de imidazo[1,2-a]piridina para su uso como inhibidores para la replica del virus de la inmunodeficiencia humana

Info

Publication number
CL2017000428A1
CL2017000428A1 CL2017000428A CL2017000428A CL2017000428A1 CL 2017000428 A1 CL2017000428 A1 CL 2017000428A1 CL 2017000428 A CL2017000428 A CL 2017000428A CL 2017000428 A CL2017000428 A CL 2017000428A CL 2017000428 A1 CL2017000428 A1 CL 2017000428A1
Authority
CL
Chile
Prior art keywords
inhibitors
immunodeficiency virus
human immunodeficiency
imidazo
virus replication
Prior art date
Application number
CL2017000428A
Other languages
English (en)
Inventor
Timothy P Conolly
Kyle J Eastman
B Narasimhulu Naidu
Kevin Peese
Original Assignee
Viiv Healthcare Uk (No 5) Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54064588&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2017000428(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Viiv Healthcare Uk (No 5) Ltd filed Critical Viiv Healthcare Uk (No 5) Ltd
Publication of CL2017000428A1 publication Critical patent/CL2017000428A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

<p>LA DIVULGACIÓN SE REFIERE EN GENERAL A COMPUESTOS DE FÓRMULA I, INCLUYENDO COMPOSICIONES Y PROCEDIMIENTOS PARA TRATAR LA INFECCIÓN POR EL VIRUS DE LA INMUNODEFICIENCIA HUMANA (VIH). LA DIVULGACIÓN PROPORCIONA NOVEDOSOS INHIBIDORES DEL VIH, COMPOSICIONES FARMACÉUTICAS QUE CONTIENEN DICHOS COMPUESTOS Y PROCEDIMIENTOS PARA USAR ESTOS COMPUESTOS EN EL TRATAMIENTO DE LA INFECCIÓN POR EL VIH.</p> <p>* incluir figura de estructura de hoja resumen pagina 76, de pdf completo</p>
CL2017000428A 2014-08-27 2017-02-22 Derivados de imidazo[1,2-a]piridina para su uso como inhibidores para la replica del virus de la inmunodeficiencia humana CL2017000428A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462042300P 2014-08-27 2014-08-27

Publications (1)

Publication Number Publication Date
CL2017000428A1 true CL2017000428A1 (es) 2017-08-18

Family

ID=54064588

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2017000428A CL2017000428A1 (es) 2014-08-27 2017-02-22 Derivados de imidazo[1,2-a]piridina para su uso como inhibidores para la replica del virus de la inmunodeficiencia humana

Country Status (13)

Country Link
US (1) US10065953B2 (es)
EP (1) EP3186254B1 (es)
JP (1) JP2017526748A (es)
KR (1) KR20170045308A (es)
CN (1) CN107001357A (es)
AU (1) AU2015306779B2 (es)
BR (1) BR112017003663A2 (es)
CA (1) CA2958591A1 (es)
CL (1) CL2017000428A1 (es)
IL (1) IL250561A0 (es)
RU (1) RU2017107715A (es)
WO (1) WO2016033009A1 (es)
ZA (1) ZA201701214B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6579549B2 (ja) 2014-05-16 2019-09-25 塩野義製薬株式会社 Ｈｉｖ複製阻害作用を有する３環性複素環誘導体
WO2016194806A1 (ja) 2015-05-29 2016-12-08 塩野義製薬株式会社 Ｈｉｖ複製阻害作用を有する含窒素３環性誘導体
AR116798A1 (es) * 2018-10-24 2021-06-16 VIIV HEALTHCARE UK Nº 5 LTD Inhibidores de la replicación del virus de la inmunodeficiencia humana
CN109232562A (zh) * 2018-10-24 2019-01-18 康化（上海）新药研发有限公司 一种7-氮杂吲哚-5-氯-6-羧酸的合成方法
WO2020197991A1 (en) 2019-03-22 2020-10-01 Gilead Sciences, Inc. Bridged tricyclic carbamoylpyridone compounds and their pharmaceutical use
CR20220418A (es) 2020-02-24 2022-10-10 Gilead Sciences Inc Compuestos tetracíclicos para el tratamiento de infecciones por vih
HUE064467T2 (hu) 2021-01-19 2024-03-28 Gilead Sciences Inc Szubsztituált piridotriazin-származékok és alkalmazásuk

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8338441B2 (en) * 2009-05-15 2012-12-25 Gilead Sciences, Inc. Inhibitors of human immunodeficiency virus replication
US8633200B2 (en) * 2010-09-08 2014-01-21 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
BR112013027096A2 (pt) * 2011-04-21 2016-12-27 Gilead Sciences Inc compostos de benzotiazol e seu uso farmacêutico
US9034882B2 (en) 2012-03-05 2015-05-19 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
MD20140063A2 (ro) * 2012-04-20 2014-12-31 Gilead Sciences, Inc. Derivaţi de acid benzotiazol-6-il acetic şi utilizarea acestora pentru tratarea unei infecţii HIV
EP2970273B1 (en) 2013-03-13 2017-03-01 VIIV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication

Also Published As

Publication number Publication date
IL250561A0 (en) 2017-03-30
CN107001357A (zh) 2017-08-01
ZA201701214B (en) 2019-07-31
RU2017107715A3 (es) 2019-03-04
EP3186254B1 (en) 2019-03-06
AU2015306779A1 (en) 2017-03-16
US10065953B2 (en) 2018-09-04
US20180222901A1 (en) 2018-08-09
AU2015306779B2 (en) 2017-11-02
EP3186254A1 (en) 2017-07-05
BR112017003663A2 (pt) 2017-11-28
KR20170045308A (ko) 2017-04-26
WO2016033009A1 (en) 2016-03-03
JP2017526748A (ja) 2017-09-14
RU2017107715A (ru) 2018-09-27
CA2958591A1 (en) 2016-03-03

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