PT3116880T - Macrociclos de ácido piridin-3-il acético como inibidores da replicação do vírus da imunodeficiência humana - Google Patents

Macrociclos de ácido piridin-3-il acético como inibidores da replicação do vírus da imunodeficiência humana

Info

Publication number
PT3116880T
PT3116880T PT157289505T PT15728950T PT3116880T PT 3116880 T PT3116880 T PT 3116880T PT 157289505 T PT157289505 T PT 157289505T PT 15728950 T PT15728950 T PT 15728950T PT 3116880 T PT3116880 T PT 3116880T
Authority
PT
Portugal
Prior art keywords
macrocycles
pyridin
inhibitors
acetic acid
immunodeficiency virus
Prior art date
Application number
PT157289505T
Other languages
English (en)
Inventor
Narasimhulu Naidu B
Original Assignee
Viiv Healthcare Uk No 5 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viiv Healthcare Uk No 5 Ltd filed Critical Viiv Healthcare Uk No 5 Ltd
Publication of PT3116880T publication Critical patent/PT3116880T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT157289505T 2014-02-20 2015-02-19 Macrociclos de ácido piridin-3-il acético como inibidores da replicação do vírus da imunodeficiência humana PT3116880T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461942244P 2014-02-20 2014-02-20

Publications (1)

Publication Number Publication Date
PT3116880T true PT3116880T (pt) 2018-05-10

Family

ID=53396542

Family Applications (1)

Application Number Title Priority Date Filing Date
PT157289505T PT3116880T (pt) 2014-02-20 2015-02-19 Macrociclos de ácido piridin-3-il acético como inibidores da replicação do vírus da imunodeficiência humana

Country Status (5)

Country Link
US (1) US9637501B2 (pt)
EP (1) EP3116880B1 (pt)
ES (1) ES2670010T3 (pt)
PT (1) PT3116880T (pt)
WO (1) WO2015127003A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9409922B2 (en) 2014-02-18 2016-08-09 Bristol-Myers Squibb Company Imidazopyridine macrocycles as inhibitors of human immunodeficiency virus replication
EP3331868A1 (en) * 2015-08-07 2018-06-13 VIIV Healthcare UK (No.5) Limited Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
AR105653A1 (es) 2015-08-11 2017-10-25 VIIV HEALTHCARE UK (Nº 5) LTD Derivados del ácido 5-(n-bencil-tetrahidroisoquinolin-6-il)-piridin-3-il acético como inhibidores de la replicación del virus de la inmunodeficiencia humana
TW201720798A (zh) 2015-09-17 2017-06-16 Ｖｉｉｖ醫療保健英國有限公司 苯并氮呯衍生物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006125178A2 (en) * 2005-05-19 2006-11-23 Xenon Pharmaceuticals Inc. Tricyclic pyridazine compounds and their uses as therapeutic agents
US7939545B2 (en) 2006-05-16 2011-05-10 Boehringer Ingelheim International Gmbh Inhibitors of human immunodeficiency virus replication
ATE541841T1 (de) 2007-11-15 2012-02-15 Boehringer Ingelheim Int Inhibitoren der replikation des human immunodeficiency virus
BRPI0819328A8 (pt) 2007-11-15 2016-02-10 Boehringer Ingelheim Int Compostos inibidores de replicação de vírus da imunodeficiência humana, composição farmacêutica e uso dos ditos compostos
EP2220046B1 (en) 2007-11-16 2014-06-18 Gilead Sciences, Inc. Inhibitors of human immunodeficiency virus replication
JP5269087B2 (ja) 2007-11-16 2013-08-21 ギリアード サイエンシス インコーポレーテッド ヒト免疫不全ウイルス複製のインヒビター
GB0908394D0 (en) 2009-05-15 2009-06-24 Univ Leuven Kath Novel viral replication inhibitors
US8338441B2 (en) 2009-05-15 2012-12-25 Gilead Sciences, Inc. Inhibitors of human immunodeficiency virus replication
GB0913636D0 (en) 2009-08-05 2009-09-16 Univ Leuven Kath Novel viral replication inhibitors
US20120316161A1 (en) 2009-12-23 2012-12-13 Katholieke Universiteit Leuven Novel antiviral compounds
US8629276B2 (en) 2012-02-15 2014-01-14 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
CN104272251B (zh) 2012-07-31 2018-10-19 惠普发展公司，有限责任合伙企业 修改系统管理存储器页表的可执行位
US8906929B2 (en) 2012-08-16 2014-12-09 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
WO2014164428A1 (en) 2013-03-13 2014-10-09 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
US9193720B2 (en) * 2014-02-20 2015-11-24 Bristol-Myers Squibb Company Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication

Also Published As

Publication number Publication date
WO2015127003A1 (en) 2015-08-27
US20170008908A1 (en) 2017-01-12
EP3116880A1 (en) 2017-01-18
US9637501B2 (en) 2017-05-02
ES2670010T3 (es) 2018-05-29
EP3116880B1 (en) 2018-03-21

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