PL3143032T3 - Nowe pochodne oksazafosforyn i ich zastosowania terapeutyczne - Google Patents
Nowe pochodne oksazafosforyn i ich zastosowania terapeutyczneInfo
- Publication number
- PL3143032T3 PL3143032T3 PL15722218T PL15722218T PL3143032T3 PL 3143032 T3 PL3143032 T3 PL 3143032T3 PL 15722218 T PL15722218 T PL 15722218T PL 15722218 T PL15722218 T PL 15722218T PL 3143032 T3 PL3143032 T3 PL 3143032T3
- Authority
- PL
- Poland
- Prior art keywords
- oxazaphosphorines
- therapeutic uses
- novel derivatives
- derivatives
- novel
- Prior art date
Links
- ZZVDXRCAGGQFAK-UHFFFAOYSA-N 2h-oxazaphosphinine Chemical class N1OC=CC=P1 ZZVDXRCAGGQFAK-UHFFFAOYSA-N 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/664—Amides of phosphorus acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
- C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14305703 | 2014-05-14 | ||
| PCT/EP2015/060706 WO2015173367A1 (en) | 2014-05-14 | 2015-05-13 | Novel derivatives of oxazaphosphorines and therapeutic uses thereof |
| EP15722218.3A EP3143032B1 (en) | 2014-05-14 | 2015-05-13 | Novel derivatives of oxazaphosphorines and therapeutic uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3143032T3 true PL3143032T3 (pl) | 2019-02-28 |
Family
ID=50771223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL15722218T PL3143032T3 (pl) | 2014-05-14 | 2015-05-13 | Nowe pochodne oksazafosforyn i ich zastosowania terapeutyczne |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10098901B2 (pl) |
| EP (1) | EP3143032B1 (pl) |
| ES (1) | ES2694025T3 (pl) |
| PL (1) | PL3143032T3 (pl) |
| PT (1) | PT3143032T (pl) |
| WO (1) | WO2015173367A1 (pl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230390312A1 (en) * | 2019-10-11 | 2023-12-07 | Institut Gustave Roussy | Novel therapeutic combinations comprising derivatives of oxazaphosphorines for the treatment of cancer |
| FR3110427B1 (fr) | 2020-05-20 | 2023-07-14 | Laboratoires Eriger | Conjugué terpenique de couplage |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2968662B1 (fr) | 2010-12-10 | 2013-11-22 | Roussy Inst Gustave | Nouveaux derives d'oxazaphosphorines pre-activees, utilisation et methode de preparation |
-
2015
- 2015-05-13 WO PCT/EP2015/060706 patent/WO2015173367A1/en not_active Ceased
- 2015-05-13 EP EP15722218.3A patent/EP3143032B1/en active Active
- 2015-05-13 PT PT15722218T patent/PT3143032T/pt unknown
- 2015-05-13 ES ES15722218.3T patent/ES2694025T3/es active Active
- 2015-05-13 US US15/310,455 patent/US10098901B2/en active Active
- 2015-05-13 PL PL15722218T patent/PL3143032T3/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3143032B1 (en) | 2018-08-01 |
| WO2015173367A1 (en) | 2015-11-19 |
| PT3143032T (pt) | 2018-11-15 |
| ES2694025T3 (es) | 2018-12-17 |
| US20170071959A1 (en) | 2017-03-16 |
| US10098901B2 (en) | 2018-10-16 |
| EP3143032A1 (en) | 2017-03-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA201608682B (en) | Boronic acid derivatives and therapeutic uses thereof | |
| EP3204360A4 (en) | Therapeutic compounds and uses thereof | |
| GB201403093D0 (en) | Therapeutic compounds and their use | |
| ZA201605639B (en) | Hppd variants and methods of use | |
| IL251246A0 (en) | Therapeutically active compounds and methods of use | |
| EP3102200A4 (en) | Therapeutic compounds and compositions | |
| ZA201606243B (en) | Hppd variants and methods of use | |
| IL249502A0 (en) | Novel therapeutic uses of benzylideneguanidine derivatives for the treatment of protein-associated diseases | |
| IL285882A (en) | Medicinal uses for l–4–chlorokynurenine | |
| EP3113771A4 (en) | Therapeutic uses of ibogaine and related compounds | |
| GB201404403D0 (en) | Compositions and methods relating to the treatment of diseases | |
| IL246721B (en) | History of 5-benzylisoquinoline for the treatment of cardiovascular diseases | |
| GB201517859D0 (en) | Novel compounds and therapeutic uses thereof | |
| SG11201605915WA (en) | Furo-3-carboxamide derivatives and methods of use | |
| ZA201802134B (en) | Therapeutic compounds and methods of use thereof | |
| GB201406172D0 (en) | Therapy and pharmaceutical composition | |
| EP3197470A4 (en) | Cis-gnetin h and trans-gnetin h as therapeutic agents | |
| PT3143032T (pt) | Novos derivados terapêuticos de oxazafosforinas e as suas utilizações terapêuticas | |
| GB201412010D0 (en) | Treatment of hypertransaminasemia | |
| PL3166642T3 (pl) | Transdermalne preparaty pergolidu i ich zastosowanie | |
| EP3212202A4 (en) | Use of therapeutic agents | |
| AU2014904330A0 (en) | Use of therapeutic agents | |
| GB201417777D0 (en) | Novel compounds and therapeutic uses thereof | |
| GB201419559D0 (en) | Therapeutic compositions and methods | |
| HK1232137B (en) | Therapeutic compounds and compositions |