ZA201202258B - Combination - Google Patents

Combination

Info

Publication number
ZA201202258B
ZA201202258B ZA2012/02258A ZA201202258A ZA201202258B ZA 201202258 B ZA201202258 B ZA 201202258B ZA 2012/02258 A ZA2012/02258 A ZA 2012/02258A ZA 201202258 A ZA201202258 A ZA 201202258A ZA 201202258 B ZA201202258 B ZA 201202258B
Authority
ZA
South Africa
Prior art keywords
combination
Prior art date
Application number
ZA2012/02258A
Other languages
English (en)
Inventor
Kurt R Auger
Kurtis Earl Bachman
Tona Morgan Gilmer
James G Greger Jr
Joel David Greshock
Sylvie Laquerre
Li Liu
Shannon Renae Morris
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of ZA201202258B publication Critical patent/ZA201202258B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/501Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA2012/02258A 2009-09-28 2012-03-28 Combination ZA201202258B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24626509P 2009-09-28 2009-09-28
US38573810P 2010-09-23 2010-09-23
PCT/US2010/050495 WO2011038380A2 (en) 2009-09-28 2010-09-28 Combination

Publications (1)

Publication Number Publication Date
ZA201202258B true ZA201202258B (en) 2012-10-31

Family

ID=43796526

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2012/02258A ZA201202258B (en) 2009-09-28 2012-03-28 Combination

Country Status (13)

Country Link
US (1) US20120245180A1 (https=)
EP (1) EP2482819A4 (https=)
JP (1) JP2013505962A (https=)
KR (1) KR20120099217A (https=)
CN (1) CN102665719A (https=)
AU (1) AU2010298020B8 (https=)
BR (1) BR112012006968A2 (https=)
CA (1) CA2775874A1 (https=)
EA (1) EA201270475A1 (https=)
IL (1) IL218846A0 (https=)
MX (1) MX2012003779A (https=)
WO (1) WO2011038380A2 (https=)
ZA (1) ZA201202258B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI505828B (zh) 2010-12-20 2015-11-01 葛蘭素史克智慧財產(第二)有限公司 新穎醫藥組成物
EP2943199A1 (en) * 2013-01-09 2015-11-18 Glaxosmithkline Intellectual Property (No. 2) Limited Combination
WO2014169843A1 (en) * 2013-04-18 2014-10-23 Shanghai Fochon Pharmaceutical Co Ltd Certain protein kinase inhibitors
WO2018126192A1 (en) * 2016-12-30 2018-07-05 Children's Medical Center Corporation Map2k1 (mek1) as a therapeutic target for arteriovenous malformations and associated disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7378423B2 (en) 2004-06-11 2008-05-27 Japan Tobacco Inc. Pyrimidine compound and medical use thereof
AU2005252110B2 (en) * 2004-06-11 2008-09-04 Shionogi & Co., Ltd. 5-amino-2,4,7-trioxo-3,4,7,8-tetrahydro-2H-pyrido[2,3-D] pyrimidine derivatives and related compounds for the treatment of cancer
PE20060608A1 (es) * 2004-10-13 2006-08-22 Wyeth Corp Analogos de 17-hidroxiwortmanina como inhibidores de pi3k
TW200815429A (en) 2006-04-11 2008-04-01 Smithkline Beecham Corp Thiazolidinedione derivatives as PI3 kinase inhibitors
CN101528231A (zh) * 2006-08-16 2009-09-09 埃克塞利希斯股份有限公司 在癌症的治疗中使用pi3k和mek调控剂
PE20090717A1 (es) 2007-05-18 2009-07-18 Smithkline Beecham Corp Derivados de quinolina como inhibidores de la pi3 quinasa

Also Published As

Publication number Publication date
EA201270475A1 (ru) 2012-11-30
AU2010298020B2 (en) 2013-09-12
BR112012006968A2 (pt) 2019-09-24
US20120245180A1 (en) 2012-09-27
AU2010298020B8 (en) 2013-10-10
EP2482819A2 (en) 2012-08-08
MX2012003779A (es) 2012-06-01
WO2011038380A3 (en) 2011-09-15
AU2010298020A1 (en) 2012-04-19
JP2013505962A (ja) 2013-02-21
IL218846A0 (en) 2012-06-28
AU2010298020A8 (en) 2013-10-10
EP2482819A4 (en) 2013-02-20
WO2011038380A2 (en) 2011-03-31
CN102665719A (zh) 2012-09-12
KR20120099217A (ko) 2012-09-07
CA2775874A1 (en) 2011-03-31

Similar Documents

Publication Publication Date Title
ZA201202612B (en) Combination
IL216337A0 (en) Pyrazinylpyrazoles
GB0904835D0 (en) Trailersafe
IL219103A0 (en) Combination
IL219786A0 (en) Combination
ZA201202494B (en) Combination
ZA201202173B (en) Combination
ZA201202495B (en) Combination
ZA201202258B (en) Combination
IL218801A0 (en) Combination
GB0904396D0 (en) Scan-me
GB0901391D0 (en) Combination
GB0906696D0 (en) Combination
EG26256A (en) Oxygen hookah
GB0921334D0 (en) Preferred combination
GB0905893D0 (en) Spacetent
AU324442S (en) Keylight
GB0901387D0 (en) VisiClip
GB0904107D0 (en) WebHook
GB0903794D0 (en) Scopesights
GB0905707D0 (en) Alcoling
GB0900367D0 (en) Shelta
GB0900395D0 (en) Kelpipe
GB0900672D0 (en) Clip-m
GB0900674D0 (en) Concrete-shifter