BR112012006968A2 - combinação - Google Patents
combinaçãoInfo
- Publication number
- BR112012006968A2 BR112012006968A2 BR112012006968A BR112012006968A BR112012006968A2 BR 112012006968 A2 BR112012006968 A2 BR 112012006968A2 BR 112012006968 A BR112012006968 A BR 112012006968A BR 112012006968 A BR112012006968 A BR 112012006968A BR 112012006968 A2 BR112012006968 A2 BR 112012006968A2
- Authority
- BR
- Brazil
- Prior art keywords
- combination
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24626509P | 2009-09-28 | 2009-09-28 | |
| US38573810P | 2010-09-23 | 2010-09-23 | |
| PCT/US2010/050495 WO2011038380A2 (en) | 2009-09-28 | 2010-09-28 | Combination |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112012006968A2 true BR112012006968A2 (pt) | 2019-09-24 |
Family
ID=43796526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012006968A BR112012006968A2 (pt) | 2009-09-28 | 2010-09-28 | combinação |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20120245180A1 (pt) |
| EP (1) | EP2482819A4 (pt) |
| JP (1) | JP2013505962A (pt) |
| KR (1) | KR20120099217A (pt) |
| CN (1) | CN102665719A (pt) |
| AU (1) | AU2010298020B8 (pt) |
| BR (1) | BR112012006968A2 (pt) |
| CA (1) | CA2775874A1 (pt) |
| EA (1) | EA201270475A1 (pt) |
| IL (1) | IL218846A0 (pt) |
| MX (1) | MX2012003779A (pt) |
| WO (1) | WO2011038380A2 (pt) |
| ZA (1) | ZA201202258B (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI505828B (zh) * | 2010-12-20 | 2015-11-01 | 葛蘭素史克智慧財產（第二）有限公司 | 新穎醫藥組成物 |
| JP2016504409A (ja) * | 2013-01-09 | 2016-02-12 | グラクソスミスクライン、インテレクチュアル、プロパティー、ナンバー２、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｎｏ．２ Ｌｉｍｉｔｅｄ | 組合せ |
| EP2986611B1 (en) * | 2013-04-18 | 2019-02-06 | Shanghai Fochon Pharmaceutical Co. Ltd | Certain protein kinase inhibitors |
| WO2018126192A1 (en) * | 2016-12-30 | 2018-07-05 | Children's Medical Center Corporation | Map2k1 (mek1) as a therapeutic target for arteriovenous malformations and associated disorders |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7378423B2 (en) | 2004-06-11 | 2008-05-27 | Japan Tobacco Inc. | Pyrimidine compound and medical use thereof |
| RS52670B (en) * | 2004-06-11 | 2013-06-28 | Japan Tobacco Inc. | 5-AMINO-2,4,7-TRIOXO-3,4,7,8-TETRAHYDRO-2H-PIRIDO (2,3-D) PYRIMIDINE DERIVATIVES AND SIMILAR COMPOUNDS FOR CANCER TREATMENT |
| JP2008515984A (ja) * | 2004-10-13 | 2008-05-15 | ワイス | Ｐｉ３ｋ阻害剤としての１７−ヒドロキシワートマニンの類似体 |
| TW200815429A (en) | 2006-04-11 | 2008-04-01 | Smithkline Beecham Corp | Thiazolidinedione derivatives as PI3 kinase inhibitors |
| CA2658725A1 (en) * | 2006-08-16 | 2008-02-21 | Exelixis, Inc. | Using pi3k and mek modulators in treatments of cancer |
| PE20090717A1 (es) * | 2007-05-18 | 2009-07-18 | Smithkline Beecham Corp | Derivados de quinolina como inhibidores de la pi3 quinasa |
-
2010
- 2010-09-28 EP EP10819634A patent/EP2482819A4/en not_active Withdrawn
- 2010-09-28 CA CA2775874A patent/CA2775874A1/en not_active Abandoned
- 2010-09-28 AU AU2010298020A patent/AU2010298020B8/en not_active Ceased
- 2010-09-28 MX MX2012003779A patent/MX2012003779A/es active IP Right Grant
- 2010-09-28 US US13/498,381 patent/US20120245180A1/en not_active Abandoned
- 2010-09-28 BR BR112012006968A patent/BR112012006968A2/pt not_active IP Right Cessation
- 2010-09-28 JP JP2012531109A patent/JP2013505962A/ja active Pending
- 2010-09-28 KR KR1020127010300A patent/KR20120099217A/ko not_active Application Discontinuation
- 2010-09-28 CN CN2010800538226A patent/CN102665719A/zh active Pending
- 2010-09-28 WO PCT/US2010/050495 patent/WO2011038380A2/en active Application Filing
- 2010-09-28 EA EA201270475A patent/EA201270475A1/ru unknown
-
2012
- 2012-03-26 IL IL218846A patent/IL218846A0/en unknown
- 2012-03-28 ZA ZA2012/02258A patent/ZA201202258B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2482819A2 (en) | 2012-08-08 |
| CA2775874A1 (en) | 2011-03-31 |
| ZA201202258B (en) | 2012-10-31 |
| AU2010298020B8 (en) | 2013-10-10 |
| KR20120099217A (ko) | 2012-09-07 |
| AU2010298020B2 (en) | 2013-09-12 |
| US20120245180A1 (en) | 2012-09-27 |
| MX2012003779A (es) | 2012-06-01 |
| CN102665719A (zh) | 2012-09-12 |
| WO2011038380A3 (en) | 2011-09-15 |
| AU2010298020A8 (en) | 2013-10-10 |
| WO2011038380A2 (en) | 2011-03-31 |
| JP2013505962A (ja) | 2013-02-21 |
| AU2010298020A1 (en) | 2012-04-19 |
| EP2482819A4 (en) | 2013-02-20 |
| IL218846A0 (en) | 2012-06-28 |
| EA201270475A1 (ru) | 2012-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |