ZA201201992B - Met inhibitors for enhancing radiotherapy efficacy - Google Patents

Met inhibitors for enhancing radiotherapy efficacy

Info

Publication number
ZA201201992B
ZA201201992B ZA2012/01992A ZA201201992A ZA201201992B ZA 201201992 B ZA201201992 B ZA 201201992B ZA 2012/01992 A ZA2012/01992 A ZA 2012/01992A ZA 201201992 A ZA201201992 A ZA 201201992A ZA 201201992 B ZA201201992 B ZA 201201992B
Authority
ZA
South Africa
Prior art keywords
met inhibitors
enhancing radiotherapy
radiotherapy efficacy
efficacy
enhancing
Prior art date
Application number
ZA2012/01992A
Other languages
English (en)
Inventor
Carla Boccaccio
Fiorella Petronzelli
Paolo Maria Comoglio
Santis Rita De
Original Assignee
Metheresis Translational Res S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metheresis Translational Res S A filed Critical Metheresis Translational Res S A
Publication of ZA201201992B publication Critical patent/ZA201201992B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
ZA2012/01992A 2011-03-18 2012-03-16 Met inhibitors for enhancing radiotherapy efficacy ZA201201992B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP11158861.2A EP2500036B1 (en) 2011-03-18 2011-03-18 MET inhibitors for enhancing radiotherapy efficacy

Publications (1)

Publication Number Publication Date
ZA201201992B true ZA201201992B (en) 2015-05-27

Family

ID=44260211

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2012/01992A ZA201201992B (en) 2011-03-18 2012-03-16 Met inhibitors for enhancing radiotherapy efficacy

Country Status (22)

Country Link
US (1) US20120237524A1 (cg-RX-API-DMAC7.html)
EP (1) EP2500036B1 (cg-RX-API-DMAC7.html)
JP (1) JP5671487B2 (cg-RX-API-DMAC7.html)
KR (1) KR101540838B1 (cg-RX-API-DMAC7.html)
CN (1) CN102688491A (cg-RX-API-DMAC7.html)
AU (1) AU2012201303B2 (cg-RX-API-DMAC7.html)
BR (1) BR102012006063B1 (cg-RX-API-DMAC7.html)
CA (1) CA2769991C (cg-RX-API-DMAC7.html)
CY (1) CY1115374T1 (cg-RX-API-DMAC7.html)
DK (1) DK2500036T3 (cg-RX-API-DMAC7.html)
EA (1) EA028590B1 (cg-RX-API-DMAC7.html)
ES (1) ES2489475T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20140729T1 (cg-RX-API-DMAC7.html)
IL (1) IL218293A (cg-RX-API-DMAC7.html)
MX (1) MX2012003084A (cg-RX-API-DMAC7.html)
PL (1) PL2500036T3 (cg-RX-API-DMAC7.html)
PT (1) PT2500036E (cg-RX-API-DMAC7.html)
RS (1) RS53468B (cg-RX-API-DMAC7.html)
SG (1) SG184637A1 (cg-RX-API-DMAC7.html)
SI (1) SI2500036T1 (cg-RX-API-DMAC7.html)
SM (1) SMT201400106B (cg-RX-API-DMAC7.html)
ZA (1) ZA201201992B (cg-RX-API-DMAC7.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9168300B2 (en) 2013-03-14 2015-10-27 Oncomed Pharmaceuticals, Inc. MET-binding agents and uses thereof
TWI782930B (zh) 2016-11-16 2022-11-11 美商再生元醫藥公司 抗met抗體,結合met之雙特異性抗原結合分子及其使用方法
IT201800009282A1 (it) * 2018-10-09 2020-04-09 Metis Prec Medicine Sb Srl Nuovo agente terapeutico per il trattamento di un tumore e/o metastasi
CN110320365B (zh) * 2019-07-06 2022-07-22 湖南莱拓福生物科技有限公司 NF-κB RelA/p65蛋白位点特异性磷酸化诊断试剂盒
US11896682B2 (en) 2019-09-16 2024-02-13 Regeneron Pharmaceuticals, Inc. Radiolabeled MET binding proteins for immuno-PET imaging and methods of use thereof
KR20250164828A (ko) 2023-03-30 2025-11-25 레볼루션 메디슨즈, 인크. Ras gtp 가수분해 유도를 위한 조성물 및 이의 용도
AU2024265078A1 (en) 2023-05-04 2025-12-11 Revolution Medicines, Inc. Combination therapy for a ras related disease or disorder
US20250049810A1 (en) 2023-08-07 2025-02-13 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
WO2025080946A2 (en) 2023-10-12 2025-04-17 Revolution Medicines, Inc. Ras inhibitors
WO2025171296A1 (en) 2024-02-09 2025-08-14 Revolution Medicines, Inc. Ras inhibitors
WO2025240847A1 (en) 2024-05-17 2025-11-20 Revolution Medicines, Inc. Ras inhibitors
WO2025255438A1 (en) 2024-06-07 2025-12-11 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI310684B (en) * 2000-03-27 2009-06-11 Bristol Myers Squibb Co Synergistic pharmaceutical kits for treating cancer
WO2004072117A2 (en) * 2003-02-13 2004-08-26 Pharmacia Corporation Antibodies to c-met for the treatment of cancers
EP2341067A1 (en) * 2003-07-18 2011-07-06 Amgen, Inc Specific binding agents to hepatocyte growth factor
HN2004000285A (es) * 2003-08-04 2006-04-27 Pfizer Prod Inc ANTICUERPOS DIRIGIDOS A c-MET
BRPI0707480A8 (pt) * 2006-02-06 2022-11-08 Vertical Bio Ag Usos de um anticorpo monoclonal, um fragmento e/ou anticorpo geneticamente engenheirado ou humanizado, de uma seqüência de nucleotídeos e de um vetor, produto, e, método para triar compostos
EP2019116A1 (en) * 2007-07-26 2009-01-28 Helmholtz-Zentrum für Infektionsforschung GmbH Inhibitor of the met-receptor and its use

Also Published As

Publication number Publication date
EP2500036B1 (en) 2014-05-07
BR102012006063A8 (pt) 2022-11-08
IL218293A (en) 2016-06-30
SG184637A1 (en) 2012-10-30
SI2500036T1 (sl) 2014-09-30
BR102012006063B1 (pt) 2023-03-07
EA201200329A3 (ru) 2013-01-30
SMT201400106B (it) 2014-11-10
CN102688491A (zh) 2012-09-26
DK2500036T3 (da) 2014-08-04
PT2500036E (pt) 2014-08-25
HRP20140729T1 (hr) 2014-08-29
HK1174539A1 (en) 2013-06-14
ES2489475T3 (es) 2014-09-02
EA028590B1 (ru) 2017-12-29
MX2012003084A (es) 2012-09-17
KR101540838B1 (ko) 2015-08-06
AU2012201303A1 (en) 2012-10-04
BR102012006063A2 (pt) 2021-11-16
EP2500036A1 (en) 2012-09-19
PL2500036T3 (pl) 2014-10-31
KR20120106582A (ko) 2012-09-26
AU2012201303B2 (en) 2013-11-07
CA2769991A1 (en) 2012-09-18
EA201200329A2 (ru) 2012-09-28
IL218293A0 (en) 2012-07-31
RS53468B (sr) 2014-12-31
CA2769991C (en) 2018-05-15
CY1115374T1 (el) 2017-01-04
JP5671487B2 (ja) 2015-02-18
US20120237524A1 (en) 2012-09-20
JP2012196206A (ja) 2012-10-18

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