ZA201000204B - Method for producing difluoromethyl-substituted pyrazole compounds - Google Patents

Method for producing difluoromethyl-substituted pyrazole compounds

Info

Publication number
ZA201000204B
ZA201000204B ZA2010/00204A ZA201000204A ZA201000204B ZA 201000204 B ZA201000204 B ZA 201000204B ZA 2010/00204 A ZA2010/00204 A ZA 2010/00204A ZA 201000204 A ZA201000204 A ZA 201000204A ZA 201000204 B ZA201000204 B ZA 201000204B
Authority
ZA
South Africa
Prior art keywords
compounds
formula
halogen
phenyl
alkyl
Prior art date
Application number
ZA2010/00204A
Other languages
English (en)
Inventor
Markus Nett
Thomas Grote
Jan Klaas Lohmann
Jochen Dietz
Sebastian Peer Smidt
Michael Rack
Thomas Zierke
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38654562&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA201000204(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Basf Se filed Critical Basf Se
Publication of ZA201000204B publication Critical patent/ZA201000204B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
ZA2010/00204A 2007-06-15 2010-01-12 Method for producing difluoromethyl-substituted pyrazole compounds ZA201000204B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07110397 2007-06-15
PCT/EP2008/057506 WO2008152138A2 (fr) 2007-06-15 2008-06-13 Procédé de préparation de composés de pyrazol substitués par difluorméthyle

Publications (1)

Publication Number Publication Date
ZA201000204B true ZA201000204B (en) 2011-10-26

Family

ID=38654562

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2010/00204A ZA201000204B (en) 2007-06-15 2010-01-12 Method for producing difluoromethyl-substituted pyrazole compounds

Country Status (16)

Country Link
US (1) US8188295B2 (fr)
EP (1) EP2158185B1 (fr)
JP (1) JP5559678B2 (fr)
KR (1) KR20100037101A (fr)
CN (1) CN101720317B (fr)
AT (1) ATE520667T1 (fr)
AU (1) AU2008263883B2 (fr)
BR (1) BRPI0812958A2 (fr)
CA (1) CA2690460A1 (fr)
DK (1) DK2158185T3 (fr)
EA (1) EA200901652A1 (fr)
ES (1) ES2369215T3 (fr)
IL (1) IL202442A0 (fr)
MX (1) MX2009013059A (fr)
WO (1) WO2008152138A2 (fr)
ZA (1) ZA201000204B (fr)

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* Cited by examiner, † Cited by third party
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DE102006039909A1 (de) * 2006-08-25 2008-03-13 Bayer Cropscience Ag Verfahren zum Herstellen von 3-Dihalomethyl-pyrazol-4-carbonsäurederivaten
KR101517254B1 (ko) 2007-06-01 2015-04-30 바스프 에스이 Ｎ-치환된 (3-디할로메틸-1-메틸-피라졸-4-일)카르복사미드의 제조 방법
JP5628677B2 (ja) 2007-10-19 2014-11-19 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ ベータ−ラクタマーゼの検出のための方法および組成物
PL2300417T3 (pl) * 2008-05-02 2015-12-31 Basf Se Sposób wytwarzania estrów kwasu 2-(aminometylideno)-4,4-difluoro-3-oksomasłowego
EP2297111B1 (fr) 2008-05-02 2012-06-20 Basf Se Procédé de production d'ester d'acide 2-(aminométhylidène)-3-oxobutyrique à substitution halogène
MX2010011433A (es) * 2008-05-05 2010-11-12 Basf Se Procedimiento para la preparacion de compuestos pirazolicos sustituidos en posiciones 1,3,4.
JP5558467B2 (ja) 2008-07-21 2014-07-23 ビーエーエスエフ ソシエタス・ヨーロピア １，３−二置換ピラゾールカルボン酸エステルの調製方法
WO2010047778A1 (fr) 2008-10-20 2010-04-29 Becton Dickinson And Company Compositions pour la détection de cibles bactériennes intracellulaires et d’autres micro-organismes cibles intracellulaires
WO2011054732A1 (fr) * 2009-11-05 2011-05-12 Basf Se Procédé d'élaboration de composés de pyrazole 1,3-disubstitués
GB201004299D0 (en) * 2010-03-15 2010-04-28 Syngenta Participations Ag Process
LT2619182T (lt) 2010-09-21 2017-01-25 Eisai R&D Management Co., Ltd. Farmacinė kompozicija
CN102295566A (zh) * 2011-07-14 2011-12-28 常熟三爱富中昊化工新材料有限公司 四氟乙基二甲基胺的制备方法
AR094929A1 (es) 2013-02-28 2015-09-09 Bristol Myers Squibb Co Derivados de fenilpirazol como inhibidores potentes de rock1 y rock2
JP6423372B2 (ja) 2013-02-28 2018-11-14 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ 強力なｒｏｃｋ１およびｒｏｃｋ２阻害剤としてのフェニルピラゾール誘導体
TWI647215B (zh) * 2013-11-11 2019-01-11 德商拜耳作物科學股份有限公司 自α,α－二鹵胺製備３,５－雙鹵烷基吡唑衍生物之方法
BR112016021874B1 (pt) * 2014-03-24 2021-03-23 Bayer Cropscience Aktiengesellschaft Processo para preparar derivados de 3,5-bis(haloalquil)pirazol a partir de alfa,alfa-dihaloaminas e cetiminas e compostos
JP2018087142A (ja) * 2015-03-30 2018-06-07 旭硝子株式会社 ３−ハロゲン化アルキルピラゾール誘導体の製造方法
CN108884051A (zh) 2016-01-28 2018-11-23 索尔维公司 卤素取代的二酮化合物、吡唑化合物及用于制造吡唑化合物的方法
CN106045910B (zh) * 2016-08-15 2017-10-10 浙江永太科技股份有限公司 一种3‑(二氟甲基)‑1‑甲基‑1h‑吡唑‑4‑羧酸的合成方法
CN112119063B (zh) 2018-05-18 2023-10-17 富士胶片株式会社 3-二氟甲基吡唑化合物的制造方法及3-二氟甲基吡唑-4-羧酸化合物的制造方法以及吡唑烷化合物
EP3650442B1 (fr) * 2018-11-09 2021-06-30 Lonza Solutions AG Procédé de préparation de d'ester d'alkyle d'acide carboxylique de pyrazole difluorométhyl et son acide

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JPS5946273A (ja) 1982-08-31 1984-03-15 Daikin Ind Ltd 含フツ素ヘテロ環化合物の製造方法
DE3934924C2 (de) 1989-10-20 1994-01-27 Huels Chemische Werke Ag Verfahren zur Herstellung von 4-Alkoxycarbonyl-3-chlormethyl-2H-pyrazolen
US5093347A (en) 1991-01-28 1992-03-03 Monsanto Company 3-difluoromethylpyrazolecarboxamide fungicides, compositions and use
US5223526A (en) 1991-12-06 1993-06-29 Monsanto Company Pyrazole carboxanilide fungicides and use
DE10215292A1 (de) 2002-02-19 2003-08-28 Bayer Cropscience Ag Disubstitutierte Pyrazolylcarbocanilide
EP1599742B1 (fr) 2003-02-25 2009-04-29 Oticon A/S Procede de detection de l'activite de la propre voix d'un utilisateur dans un dispositif de communication
DE10331496A1 (de) 2003-07-01 2005-01-27 Bayer Cropscience Ag Verfahren zum Herstellen von Difluoracetessigsäurealkylestern
DE10349500A1 (de) * 2003-10-23 2005-06-02 Bayer Cropscience Ag Verfahren zum Herstellen von 2-Dihalogenacyl-3-amino-acrylsäureestern und 3-Dihalogenmethyl-pyrazol-4-carbonsäureestern
DE10351088A1 (de) 2003-10-31 2005-06-02 Bayer Cropscience Gmbh Verfahren zum Herstellen von fluormethyl-substituierten Heterocyclen
EP1928838B1 (fr) 2005-09-16 2012-10-24 Syngenta Participations AG Procédé de production d'amides
TW200732320A (en) 2005-10-31 2007-09-01 Biolipox Ab Pyrazoles useful in the treatment of inflammation
DE102006039909A1 (de) * 2006-08-25 2008-03-13 Bayer Cropscience Ag Verfahren zum Herstellen von 3-Dihalomethyl-pyrazol-4-carbonsäurederivaten
ATE455105T1 (de) * 2006-11-03 2010-01-15 Basf Se Verfahren zur herstellung von difluormethylpyrazolylcarboxylaten
BRPI0720410A2 (pt) 2006-12-21 2013-12-31 Basf Se Processos para a preparação de composto, para a preparação de amidas, e, compostos.
KR101517254B1 (ko) 2007-06-01 2015-04-30 바스프 에스이 Ｎ-치환된 (3-디할로메틸-1-메틸-피라졸-4-일)카르복사미드의 제조 방법

Also Published As

Publication number Publication date
US20100184994A1 (en) 2010-07-22
EP2158185A2 (fr) 2010-03-03
EA200901652A1 (ru) 2010-06-30
BRPI0812958A2 (pt) 2014-12-09
ATE520667T1 (de) 2011-09-15
MX2009013059A (es) 2010-01-15
DK2158185T3 (da) 2011-11-21
CA2690460A1 (fr) 2008-12-18
IL202442A0 (en) 2010-06-30
KR20100037101A (ko) 2010-04-08
CN101720317A (zh) 2010-06-02
WO2008152138A2 (fr) 2008-12-18
JP2010529976A (ja) 2010-09-02
EP2158185B1 (fr) 2011-08-17
WO2008152138A3 (fr) 2009-05-28
AU2008263883B2 (en) 2014-03-13
AU2008263883A1 (en) 2008-12-18
CN101720317B (zh) 2014-07-09
JP5559678B2 (ja) 2014-07-23
ES2369215T3 (es) 2011-11-28
US8188295B2 (en) 2012-05-29

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