ZA200907537B - A method for the preparation of mirtazapine - Google Patents

A method for the preparation of mirtazapine

Info

Publication number
ZA200907537B
ZA200907537B ZA200907537A ZA200907537A ZA200907537B ZA 200907537 B ZA200907537 B ZA 200907537B ZA 200907537 A ZA200907537 A ZA 200907537A ZA 200907537 A ZA200907537 A ZA 200907537A ZA 200907537 B ZA200907537 B ZA 200907537B
Authority
ZA
South Africa
Prior art keywords
mirtazapine
preparation
Prior art date
Application number
ZA200907537A
Other languages
English (en)
Inventor
Gerardus Johannes Kemperman
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Nv filed Critical Organon Nv
Publication of ZA200907537B publication Critical patent/ZA200907537B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200907537A 2007-04-11 2009-10-27 A method for the preparation of mirtazapine ZA200907537B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07105985 2007-04-11

Publications (1)

Publication Number Publication Date
ZA200907537B true ZA200907537B (en) 2010-07-28

Family

ID=38474342

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200907537A ZA200907537B (en) 2007-04-11 2009-10-27 A method for the preparation of mirtazapine

Country Status (8)

Country Link
EP (1) EP2146993B1 (enExample)
JP (1) JP5635905B2 (enExample)
CN (1) CN101679431B (enExample)
AR (1) AR066005A1 (enExample)
CA (1) CA2684021A1 (enExample)
MX (1) MX2009010967A (enExample)
WO (1) WO2008125578A2 (enExample)
ZA (1) ZA200907537B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG191831A1 (en) * 2011-03-31 2013-08-30 Kaneka Corp Process for preparing cyclic amine compounds
SI3261645T1 (sl) 2015-02-27 2021-08-31 Dechra Limited Stimulacija apetita, uravnavanje izgube mase in zdravljenje anoreksije pri psih in mačkah
CN121204204A (zh) * 2025-11-27 2025-12-26 山东静远药业有限公司 一种苯磺酸米洛巴林关键中间体的对映体杂质的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL189199C (nl) * 1975-04-05 1993-02-01 Akzo Nv Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten.
PT1030667E (pt) 1997-11-14 2005-06-30 Akzo Nobel Nv Utilizacao de mirtazapina para o fabrico de um medicamento para o tratamento de apenas do sono
CN1679586A (zh) 1999-04-19 2005-10-12 特瓦制药工业有限公司 含哌嗪环化合物的新型合成和结晶方法
WO2001025185A1 (en) 1999-09-30 2001-04-12 Sumika Fine Chemicals Co., Ltd. Process for the preparation of a piperazine derivative
AU6474200A (en) 1999-12-13 2001-06-18 Sumika Fine Chemicals Co., Ltd. Process for the preparation of a pyridinemethanol compound
ES2258071T3 (es) 2000-02-11 2006-08-16 Akzo Nobel N.V. Utilizacion de mirtazepina para trastornos del sueño.
US7265223B2 (en) 2001-09-14 2007-09-04 Medichem, S.A. Intermediate compounds for the preparation of mirtazapine and production methods thereof
US6806283B2 (en) * 2002-05-06 2004-10-19 Virginia Commonwealth University Selective serotonin receptor antagonists and therapeutic applications thereof
UA83666C2 (ru) * 2003-07-10 2008-08-11 Н.В. Органон Способ получения энантиомерно чистого миртазапина
WO2005012326A1 (en) * 2003-08-01 2005-02-10 Tanabe Seiyaku Co., Ltd. Novel compounds having inhibitory activity against sodium-dependant transporter
JP2007284358A (ja) 2006-04-13 2007-11-01 Sumitomo Chemical Co Ltd 光学活性なピペラジン化合物の製造方法
TW200815370A (en) * 2006-06-16 2008-04-01 Organon Nv Stereoselective synthesis of (S)-1-methyl-3-phenylpiperazine

Also Published As

Publication number Publication date
JP5635905B2 (ja) 2014-12-03
JP2010523620A (ja) 2010-07-15
AR066005A1 (es) 2009-07-15
CA2684021A1 (en) 2008-10-23
WO2008125578A2 (en) 2008-10-23
CN101679431A (zh) 2010-03-24
MX2009010967A (es) 2009-12-15
EP2146993A2 (en) 2010-01-27
EP2146993B1 (en) 2015-08-05
WO2008125578A3 (en) 2008-12-24
CN101679431B (zh) 2013-08-14

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