ZA200905796B - Purinyl derivatives and their use as potassium channel modulators - Google Patents
Purinyl derivatives and their use as potassium channel modulatorsInfo
- Publication number
- ZA200905796B ZA200905796B ZA200905796A ZA200905796A ZA200905796B ZA 200905796 B ZA200905796 B ZA 200905796B ZA 200905796 A ZA200905796 A ZA 200905796A ZA 200905796 A ZA200905796 A ZA 200905796A ZA 200905796 B ZA200905796 B ZA 200905796B
- Authority
- ZA
- South Africa
- Prior art keywords
- potassium channel
- channel modulators
- purinyl derivatives
- purinyl
- derivatives
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/24—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one nitrogen and one sulfur atom
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Psychology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Transplantation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200700482 | 2007-03-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200905796B true ZA200905796B (en) | 2010-10-27 |
Family
ID=41658005
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200905796A ZA200905796B (en) | 2007-03-28 | 2008-03-27 | Purinyl derivatives and their use as potassium channel modulators |
Country Status (10)
Country | Link |
---|---|
US (2) | US20120004246A1 (ja) |
EP (1) | EP2402341B1 (ja) |
JP (5) | JP2010522719A (ja) |
KR (1) | KR101564233B1 (ja) |
CN (1) | CN101646669B (ja) |
BR (1) | BRPI0808746B8 (ja) |
NZ (1) | NZ579248A (ja) |
RU (1) | RU2468026C2 (ja) |
UA (1) | UA98482C2 (ja) |
ZA (1) | ZA200905796B (ja) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100035934A1 (en) * | 2007-02-02 | 2010-02-11 | Neurosearch A/S | Pyridinyl-pyrazole derivatives and their use as potassium channel modulators |
US20100130516A1 (en) * | 2007-03-28 | 2010-05-27 | Neurosearch A/S | Purinyl derivatives and their use as potassium channel modulators |
JP2010522719A (ja) * | 2007-03-28 | 2010-07-08 | ノイロサーチ アクティーゼルスカブ | プリニル誘導体及びカリウムチャネルモジュレーターとしてのそれらの使用 |
US8415358B2 (en) | 2007-09-17 | 2013-04-09 | Neurosearch A/S | Pyrazine derivatives and their use as potassium channel modulators |
AU2009251291B2 (en) * | 2008-05-30 | 2013-05-02 | F. Hoffmann-La Roche Ag | Purine PI3K inhibitor compounds and methods of use |
WO2010026087A1 (en) * | 2008-09-02 | 2010-03-11 | Neurosearch A/S | Pyrazolyl-pyrimidine derivatives and their use as potassium channel modulators |
WO2010034707A1 (en) * | 2008-09-26 | 2010-04-01 | Neurosearch A/S | Substituted purinyl-pyrazol derivatives and their use as potassium channel modulators |
US20110237607A1 (en) * | 2008-09-26 | 2011-09-29 | Neurosearch A/S | Substituted purinyl-pyrazol derivatives and their use as potassium channel modulators |
EP2438069A1 (en) | 2009-04-01 | 2012-04-11 | NeuroSearch A/S | Substituted [1,2,4]triazolo[1,5-a]pyrimidines and their use as potassium channel modulators |
US8765770B2 (en) | 2009-04-01 | 2014-07-01 | Ataxion, Inc. | Substituted [1,2,4]triazolo[1,5-a]pyrimidines and their use as potassium channel modulators |
AR079814A1 (es) | 2009-12-31 | 2012-02-22 | Otsuka Pharma Co Ltd | Compuestos heterociclicos, composiciones farmaceuticas que los contienen y sus usos |
JP6121658B2 (ja) * | 2011-06-29 | 2017-04-26 | 大塚製薬株式会社 | 治療用化合物、及び関連する使用の方法 |
CA2876780A1 (en) | 2012-06-26 | 2014-01-03 | Saniona Aps | A phenyl triazole derivative and its use for modulating the gabaa receptor complex |
RU2015137298A (ru) * | 2013-03-05 | 2017-04-10 | Ф. Хоффманн-Ля Рош Аг | Ингибиторы тирозинкиназы брутона |
WO2014135480A1 (en) * | 2013-03-06 | 2014-09-12 | Bayer Pharma Aktiengesellschaft | Substituted thiazolopyrimidines |
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-
2008
- 2008-03-27 JP JP2010500273A patent/JP2010522719A/ja active Pending
- 2008-03-27 JP JP2010500276A patent/JP2010522722A/ja active Pending
- 2008-03-27 UA UAA200908793A patent/UA98482C2/ru unknown
- 2008-03-27 JP JP2010500274A patent/JP2010522720A/ja active Pending
- 2008-03-27 CN CN2008800099645A patent/CN101646669B/zh active Active
- 2008-03-27 US US12/593,220 patent/US20120004246A1/en not_active Abandoned
- 2008-03-27 JP JP2010500275A patent/JP2010522721A/ja active Pending
- 2008-03-27 NZ NZ579248A patent/NZ579248A/en unknown
- 2008-03-27 EP EP11182703.6A patent/EP2402341B1/en active Active
- 2008-03-27 BR BRPI0808746A patent/BRPI0808746B8/pt active IP Right Grant
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- 2008-03-27 JP JP2010500272A patent/JP5703432B2/ja active Active
- 2008-03-27 KR KR1020097020281A patent/KR101564233B1/ko active IP Right Grant
- 2008-03-27 US US12/593,269 patent/US20100105705A1/en not_active Abandoned
- 2008-03-27 ZA ZA200905796A patent/ZA200905796B/xx unknown
Also Published As
Publication number | Publication date |
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JP2010522719A (ja) | 2010-07-08 |
KR101564233B1 (ko) | 2015-10-29 |
RU2468026C2 (ru) | 2012-11-27 |
JP2010522720A (ja) | 2010-07-08 |
CN101646669B (zh) | 2013-09-04 |
EP2402341A3 (en) | 2014-11-12 |
NZ579248A (en) | 2011-08-26 |
UA98482C2 (ru) | 2012-05-25 |
US20100105705A1 (en) | 2010-04-29 |
EP2402341B1 (en) | 2017-10-25 |
BRPI0808746B8 (pt) | 2021-05-25 |
EP2402341A2 (en) | 2012-01-04 |
KR20100014648A (ko) | 2010-02-10 |
JP2010522722A (ja) | 2010-07-08 |
JP2010522718A (ja) | 2010-07-08 |
CN101646669A (zh) | 2010-02-10 |
RU2009132881A (ru) | 2011-05-10 |
JP2010522721A (ja) | 2010-07-08 |
BRPI0808746B1 (pt) | 2020-09-24 |
JP5703432B2 (ja) | 2015-04-22 |
US20120004246A1 (en) | 2012-01-05 |
BRPI0808746A2 (pt) | 2014-08-19 |
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