ZA200904530B - Solid of macrolide compound, method for production thereof, and pharmaceutical composition comprising the same - Google Patents

Solid of macrolide compound, method for production thereof, and pharmaceutical composition comprising the same

Info

Publication number
ZA200904530B
ZA200904530B ZA200904530A ZA200904530A ZA200904530B ZA 200904530 B ZA200904530 B ZA 200904530B ZA 200904530 A ZA200904530 A ZA 200904530A ZA 200904530 A ZA200904530 A ZA 200904530A ZA 200904530 B ZA200904530 B ZA 200904530B
Authority
ZA
South Africa
Prior art keywords
solid
production
pharmaceutical composition
same
macrolide compound
Prior art date
Application number
ZA200904530A
Other languages
English (en)
Inventor
Hiroshi Ishihara
Manabu Sasho
Keizo Sato
Takashi Kamahara
Masashi Yoshida
Original Assignee
Eisai R&D Man Co Ltd
Mercian Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd, Mercian Corp filed Critical Eisai R&D Man Co Ltd
Publication of ZA200904530B publication Critical patent/ZA200904530B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200904530A 2007-01-29 2008-01-28 Solid of macrolide compound, method for production thereof, and pharmaceutical composition comprising the same ZA200904530B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2007017491 2007-01-29

Publications (1)

Publication Number Publication Date
ZA200904530B true ZA200904530B (en) 2010-09-29

Family

ID=39674155

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200904530A ZA200904530B (en) 2007-01-29 2008-01-28 Solid of macrolide compound, method for production thereof, and pharmaceutical composition comprising the same

Country Status (17)

Country Link
US (1) US7790887B2 (fr)
EP (1) EP2116542A4 (fr)
JP (1) JPWO2008093853A1 (fr)
KR (1) KR20090104002A (fr)
CN (1) CN101616912A (fr)
AR (1) AR065045A1 (fr)
AU (1) AU2008211950A1 (fr)
BR (1) BRPI0805837A2 (fr)
CA (1) CA2673734A1 (fr)
CL (1) CL2008000231A1 (fr)
IL (1) IL200103A0 (fr)
MX (1) MX2009008068A (fr)
NZ (1) NZ575828A (fr)
PE (1) PE20081705A1 (fr)
RU (1) RU2009132476A (fr)
WO (1) WO2008093853A1 (fr)
ZA (1) ZA200904530B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI334866B (en) * 2002-05-29 2010-12-21 Mercian Corp Novel physiologically active substances
BRPI0805837A2 (pt) 2007-01-29 2011-08-30 Eisai R&D Man Co Ltd forma sólida de um composto, método para preparação dos cristais, composição farmacêutica, método de tratamento de cáncer, e uso do composto sólido
EP2168961A1 (fr) * 2007-07-06 2010-03-31 Eisai R&D Management Co., Ltd. Procédé de fabrication d'un composé macrolide et intermédiaire
IL303335B1 (en) 2018-04-09 2024-09-01 Eisai R&D Man Co Ltd Palladianolide compounds and their use
TWI834655B (zh) 2018-04-12 2024-03-11 日商衛材R&D企管股份有限公司 特定芳基普拉二烯內酯化合物及其使用方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL27183A (en) 1966-02-01 1970-07-19 Upjohn Co Parenteral composition comprising freeze dried mannitol
JPS6054933B2 (ja) 1978-01-27 1985-12-03 小野薬品工業株式会社 プロスタグランジン及びプロスタグランジン類似化合物製剤の安定化法
JPH04352783A (ja) 1991-05-27 1992-12-07 Taisho Pharmaceut Co Ltd 12員環マクロライド系化合物
PL316995A1 (en) 1994-04-25 1997-03-03 Kyowa Hakko Kogyo Kk Method of stabilising the dx-52-1 compound and freeze dried compositions thereof
EP1192147A1 (fr) 1999-06-03 2002-04-03 THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Mycolactone et composes et compositions qui y sont lies ainsi que procedes d'utilisation correspondants
US6391903B1 (en) 1999-09-09 2002-05-21 Sankyo Company, Limited Triazole derivatives having antifungal activity
JP3240129B1 (ja) * 1999-09-09 2001-12-17 三共株式会社 トリアゾール抗真菌剤
JP4953501B2 (ja) * 1999-09-30 2012-06-13 大塚化学株式会社 3−セフェム誘導体結晶の製造方法
AU2001278155A1 (en) 2000-08-03 2002-02-18 Kosan Biosciences, Inc. Fermentation and purification of mycolactones
TWI311558B (en) 2001-02-01 2009-07-01 Mercian Corporatio Novel physiologically active substance
TWI233361B (en) 2001-04-13 2005-06-01 Gen Hospital Corp Methods of preventing UVB-induced skin damage
TWI334866B (en) 2002-05-29 2010-12-21 Mercian Corp Novel physiologically active substances
JP2004269488A (ja) 2002-06-06 2004-09-30 Hayashibara Biochem Lab Inc 結晶α−D−グルコシルα−D−ガラクトシドとこれを含有する糖質及びこれらの製造方法並びに用途
BR0313039A (pt) 2002-07-31 2005-08-09 Mercian Corp Composto, medicamento, composição farmacêutica, método para prevenir ou tratar uma doença contra a qual um controle da expressão do gene é eficaz, método para prevenir ou tratar uma doença contra a qual a supressão da produção de vegf é eficaz, método para prevenir ou tratar uma doença contra a qual uma inibição da angiogênese é eficaz, uso do composto, método para produzir um composto 9-desoxi 1107, linhagem streptomyces sp. a-1543 (ferm bp-8442), método de produzir um composto 6- desoxi, e linhagem a-1544 (ferm bp-8446) ou linhagem a-1545 (ferm bp-8447)
US7576204B2 (en) 2002-07-31 2009-08-18 Mercian Corporation Heterocyclic macrolide pharmaceutical agent, a method of producing the same and use of the same
CA2507641A1 (fr) 2002-11-29 2004-06-17 Mercian Corporation Procede de production d'un compose macrolide
KR100732100B1 (ko) 2003-05-07 2007-06-27 에자이 알앤드디 매니지먼트 가부시키가이샤 메틸코발라민 함유 동결 건조 제제 및 그의 제조 방법
CA2553573A1 (fr) 2004-01-29 2005-08-11 Eisai R & D Management Co., Ltd. Methode de stabilisation d'un compose de macrolide
US20080280288A1 (en) * 2004-02-06 2008-11-13 Toshimitsu Uenaka Assay Method to Predict Sensitivity of Cancer Cell to Anticancer Drug
JP2007269628A (ja) * 2004-05-28 2007-10-18 Takeda Chem Ind Ltd 医薬化合物の結晶
JP2007519758A (ja) * 2004-12-01 2007-07-19 テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ 結晶マクロライドの生成方法
KR100598119B1 (ko) 2005-01-17 2006-07-10 삼성전자주식회사 디스플레이장치 및 그 제어방법
CA2607639A1 (fr) 2005-05-11 2006-11-16 Eisai R & D Management Co., Ltd. Cristal de derive d'indole comportant un cycle piperidine et procede de synthese dudit cristal
EP1935893A4 (fr) 2005-10-13 2009-07-22 Eisai R&D Man Co Ltd Synthèse totale de pladienolide b et de pladienolide d
CA2659562A1 (fr) 2006-08-14 2008-02-21 Eisai R&D Management Co., Ltd. Preparation lyophilisee stable
BRPI0805837A2 (pt) 2007-01-29 2011-08-30 Eisai R&D Man Co Ltd forma sólida de um composto, método para preparação dos cristais, composição farmacêutica, método de tratamento de cáncer, e uso do composto sólido

Also Published As

Publication number Publication date
JPWO2008093853A1 (ja) 2010-05-20
CL2008000231A1 (es) 2008-05-30
EP2116542A1 (fr) 2009-11-11
US7790887B2 (en) 2010-09-07
BRPI0805837A2 (pt) 2011-08-30
EP2116542A4 (fr) 2011-05-04
CN101616912A (zh) 2009-12-30
AR065045A1 (es) 2009-05-13
IL200103A0 (en) 2010-04-15
KR20090104002A (ko) 2009-10-05
US20080214564A1 (en) 2008-09-04
PE20081705A1 (es) 2008-12-22
NZ575828A (en) 2011-04-29
CA2673734A1 (fr) 2008-08-07
RU2009132476A (ru) 2011-03-10
AU2008211950A1 (en) 2008-08-07
WO2008093853A1 (fr) 2008-08-07
MX2009008068A (es) 2009-11-18

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