ZA200902711B - Compositions and methods for modulating c-kit and PDGFR receptors - Google Patents
Compositions and methods for modulating c-kit and PDGFR receptorsInfo
- Publication number
- ZA200902711B ZA200902711B ZA200902711A ZA200902711A ZA200902711B ZA 200902711 B ZA200902711 B ZA 200902711B ZA 200902711 A ZA200902711 A ZA 200902711A ZA 200902711 A ZA200902711 A ZA 200902711A ZA 200902711 B ZA200902711 B ZA 200902711B
- Authority
- ZA
- South Africa
- Prior art keywords
- modulating
- kit
- compositions
- methods
- pdgfr receptors
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Addiction (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86243006P | 2006-10-20 | 2006-10-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200902711B true ZA200902711B (en) | 2010-05-26 |
Family
ID=39027274
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200902711A ZA200902711B (en) | 2006-10-20 | 2009-04-20 | Compositions and methods for modulating c-kit and PDGFR receptors |
Country Status (25)
Country | Link |
---|---|
US (2) | US7678792B2 (es) |
EP (1) | EP2076513A1 (es) |
JP (1) | JP2010506948A (es) |
KR (1) | KR101079520B1 (es) |
CN (1) | CN101528744A (es) |
AR (1) | AR063343A1 (es) |
AU (1) | AU2007309279B2 (es) |
BR (1) | BRPI0718162A2 (es) |
CA (1) | CA2667010A1 (es) |
CL (1) | CL2007003005A1 (es) |
CO (1) | CO6170361A2 (es) |
CR (1) | CR10717A (es) |
EA (1) | EA200900573A1 (es) |
EC (1) | ECSP099353A (es) |
IL (1) | IL197875A0 (es) |
MA (1) | MA30888B1 (es) |
MX (1) | MX2009004141A (es) |
NI (1) | NI200900061A (es) |
NO (1) | NO20091949L (es) |
PE (1) | PE20081262A1 (es) |
SM (1) | SMP200900027B (es) |
TN (1) | TN2009000145A1 (es) |
TW (1) | TW200825081A (es) |
WO (1) | WO2008051757A1 (es) |
ZA (1) | ZA200902711B (es) |
Families Citing this family (76)
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AU2003220222A1 (en) | 2002-03-13 | 2003-09-29 | Signum Biosciences, Inc. | Modulation of protein methylation and phosphoprotein phosphate |
CA2601777A1 (en) | 2005-02-03 | 2006-08-10 | Signum Biosciences, Inc. | Compositions and methods for enhancing cognitive function |
US7923041B2 (en) | 2005-02-03 | 2011-04-12 | Signum Biosciences, Inc. | Compositions and methods for enhancing cognitive function |
US8188113B2 (en) * | 2006-09-14 | 2012-05-29 | Deciphera Pharmaceuticals, Inc. | Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases |
US7897762B2 (en) | 2006-09-14 | 2011-03-01 | Deciphera Pharmaceuticals, Llc | Kinase inhibitors useful for the treatment of proliferative diseases |
CN101553206B (zh) | 2006-11-09 | 2012-11-21 | 爱尔康研究有限公司 | 用于药物递送的水不溶性聚合物基质 |
TWI498115B (zh) * | 2007-12-27 | 2015-09-01 | Daiichi Sankyo Co Ltd | 咪唑羰基化合物 |
BRPI0908849A2 (pt) * | 2008-02-22 | 2015-08-25 | Irm Llc | Composto e composições como c-kit e inibidores de pdgfr quinase |
EP2282735B1 (en) | 2008-04-21 | 2019-01-16 | Signum Biosciences, Inc. | Pp2a modulators for treating alzheimer, parkinson, diabetes |
FR2930552B1 (fr) * | 2008-04-24 | 2012-10-12 | Centre Nat Rech Scient | N-acylthiourees et n-acylurees inhibiteurs de la voie de signalisation des proteines hedgehog |
CN102089278A (zh) * | 2008-06-11 | 2011-06-08 | Irm责任有限公司 | 用于治疗疟疾的化合物和组合物 |
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AU2009308853A1 (en) * | 2008-10-29 | 2010-05-06 | Deciphera Pharmaceuticals, Llc | Cyclopropane amides and analogs exhibiting anti-cancer and anti-proliferative activities |
AR074776A1 (es) * | 2008-12-18 | 2011-02-09 | Sanofi Aventis | Metodo para tratar la degeneracion macular; modulando el sistema inmunitario del paciente |
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EP2396324A1 (en) * | 2009-02-13 | 2011-12-21 | Fovea Pharmaceuticals | Ý1, 2, 4¨triazolo ý1, 5 -a¨pyridines as kinase inhibitors |
EA201270498A1 (ru) | 2009-10-09 | 2012-11-30 | Афраксис, Инк. | 8-этил-6-(арил)пиридо[2,3-d]пиримидин-7(8h)-оны для лечения заболеваний цнс |
WO2011092128A1 (en) | 2010-01-29 | 2011-08-04 | Boehringer Ingelheim International Gmbh | Substituted naphthyridines and their use as syk kinase inhibitors |
EP2531498B1 (en) | 2010-02-05 | 2016-07-13 | Novartis AG | Compounds and compositions as protein kinase inhibitors |
AR085091A1 (es) * | 2011-01-26 | 2013-09-11 | Kolltan Pharmaceuticals Inc | Anticuerpos anti-kit y sus usos |
EP2701510B1 (en) | 2011-04-25 | 2017-02-15 | Usher III Initiative | Pyrazolopyridazines and methods for treating retinal-degenerative diseases and hearing loss associated with usher syndrome |
CA2843022C (en) | 2011-07-26 | 2019-09-24 | Boehringer Ingelheim International Gmbh | Substituted quinolines and their use as medicaments |
AU2012315953A1 (en) * | 2011-09-30 | 2014-04-03 | Kineta, Inc. | Anti-viral compounds |
EP2861576B1 (en) | 2012-05-15 | 2018-01-10 | Novartis AG | Benzamide derivatives for inhibiting the activity of abl1, abl2 and bcr-abl1 |
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ES2646777T3 (es) | 2012-05-15 | 2017-12-15 | Novartis Ag | Derivados de pirimidina, piridina y pirazina amida sustituidos con tiazol o imidazol y compuestos relacionados como inhibidores de ABL1, ABL2 y BCR-ABL1 para el tratamiento del cáncer, infecciones víricas específicas y trastornos específicos del CNS |
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JP6768639B2 (ja) | 2014-05-23 | 2020-10-21 | セルデックス セラピューティクス,インコーポレーテッド | 好酸球又はマスト細胞関連障害の治療 |
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CN111170998B (zh) | 2014-11-05 | 2023-04-11 | 益方生物科技(上海)股份有限公司 | 嘧啶或吡啶类化合物、其制备方法和医药用途 |
WO2016105484A1 (en) | 2014-12-23 | 2016-06-30 | Proteostasis Therapeutics, Inc. | Derivatives of 5-(hetero)arylpyrazol-3-carboxylic amide or 1-(hetero)aryltriazol-4-carboxylic amide useful for the treatment of inter alia cystic fibrosis |
WO2016105468A1 (en) | 2014-12-23 | 2016-06-30 | Proteostasis Therapeutics, Inc. | Derivatives of 3-heteroarylisoxazol-5-carboxylic amide useful for the treatment of inter alia cystic fibrosis |
MA41253A (fr) | 2014-12-23 | 2017-10-31 | Proteostasis Therapeutics Inc | Composés, compositions et procédés pour augmenter l'activité du cftr |
CA2971850A1 (en) | 2014-12-23 | 2016-06-30 | Proteostasis Therapeutics, Inc. | Derivatives of 5-phenyl- or 5-heteroarylthiazol-2-carboxylic amide useful for the treatment of inter alia cystic fibrosis |
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TN2009000145A1 (en) | 2010-10-18 |
US20100081656A1 (en) | 2010-04-01 |
US20080176846A1 (en) | 2008-07-24 |
KR20090054477A (ko) | 2009-05-29 |
SMP200900027B (it) | 2010-01-19 |
AR063343A1 (es) | 2009-01-21 |
US7678792B2 (en) | 2010-03-16 |
CN101528744A (zh) | 2009-09-09 |
AU2007309279A1 (en) | 2008-05-02 |
CR10717A (es) | 2009-07-02 |
MX2009004141A (es) | 2009-05-01 |
NI200900061A (es) | 2010-03-10 |
WO2008051757A1 (en) | 2008-05-02 |
CL2007003005A1 (es) | 2008-05-23 |
US8106068B2 (en) | 2012-01-31 |
AU2007309279B2 (en) | 2011-03-24 |
MA30888B1 (fr) | 2009-11-02 |
EP2076513A1 (en) | 2009-07-08 |
JP2010506948A (ja) | 2010-03-04 |
BRPI0718162A2 (pt) | 2013-11-26 |
CO6170361A2 (es) | 2010-06-18 |
PE20081262A1 (es) | 2008-10-29 |
IL197875A0 (en) | 2009-12-24 |
EA200900573A1 (ru) | 2009-10-30 |
TW200825081A (en) | 2008-06-16 |
CA2667010A1 (en) | 2008-05-02 |
SMAP200900027A (it) | 2009-07-14 |
KR101079520B1 (ko) | 2011-11-03 |
NO20091949L (no) | 2009-05-19 |
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