ZA200901189B - Aminoacyl prodrug derivatives and medicaments for treatment of thromboembolic disorders - Google Patents

Aminoacyl prodrug derivatives and medicaments for treatment of thromboembolic disorders

Info

Publication number
ZA200901189B
ZA200901189B ZA200901189A ZA200901189A ZA200901189B ZA 200901189 B ZA200901189 B ZA 200901189B ZA 200901189 A ZA200901189 A ZA 200901189A ZA 200901189 A ZA200901189 A ZA 200901189A ZA 200901189 B ZA200901189 B ZA 200901189B
Authority
ZA
South Africa
Prior art keywords
medicaments
treatment
prodrug derivatives
thromboembolic disorders
aminoacyl
Prior art date
Application number
ZA200901189A
Other languages
English (en)
Inventor
Hans-Georg Lerchen
Ursula Krenz
Karl-Heinz Schlemmer
Elisabeth Perzborn
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of ZA200901189B publication Critical patent/ZA200901189B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200901189A 2006-08-24 2009-02-19 Aminoacyl prodrug derivatives and medicaments for treatment of thromboembolic disorders ZA200901189B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102006039589A DE102006039589A1 (de) 2006-08-24 2006-08-24 Aminoacyl-Prodrugs II

Publications (1)

Publication Number Publication Date
ZA200901189B true ZA200901189B (en) 2010-04-28

Family

ID=38694946

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200901189A ZA200901189B (en) 2006-08-24 2009-02-19 Aminoacyl prodrug derivatives and medicaments for treatment of thromboembolic disorders

Country Status (16)

Country Link
US (1) US8362015B2 (fr)
EP (1) EP2084154B1 (fr)
JP (1) JP5352461B2 (fr)
KR (1) KR20090057266A (fr)
CN (1) CN101547921B (fr)
AU (1) AU2007287749B2 (fr)
BR (1) BRPI0715741A2 (fr)
CA (1) CA2661414C (fr)
DE (1) DE102006039589A1 (fr)
ES (1) ES2399069T3 (fr)
HK (1) HK1137987A1 (fr)
IL (1) IL197079A0 (fr)
MX (1) MX2009001977A (fr)
RU (1) RU2456283C9 (fr)
WO (1) WO2008022786A1 (fr)
ZA (1) ZA200901189B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006007146A1 (de) * 2006-02-16 2007-08-23 Bayer Healthcare Ag Aminoacyl-Prodrugs
DE102007028407A1 (de) * 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
DE102007028319A1 (de) * 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
US7816355B1 (en) 2009-04-28 2010-10-19 Apotex Pharmachem Inc Processes for the preparation of rivaroxaban and intermediates thereof
DE102010028362A1 (de) 2010-04-29 2011-11-03 Bayer Schering Pharma Aktiengesellschaft Herstellverfahren
CA2815063C (fr) * 2010-10-18 2016-11-22 Apotex Pharmachem Inc. Procedes de preparation de rivaroxaban et ses intermediaires
AU2013368847B2 (en) * 2012-12-26 2017-03-16 Wanbury Ltd. Aldehyde derivative of substitute oxazolidinones
JP6998780B2 (ja) 2018-02-02 2022-01-18 株式会社デンソー 冷凍サイクル装置

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7425541B2 (en) * 1998-12-11 2008-09-16 Medarex, Inc. Enzyme-cleavable prodrug compounds
DK1196414T3 (da) * 1999-06-25 2003-11-24 Vertex Pharma Prolægemiddel af carbamathæmmer for IMPDH
DE19962924A1 (de) * 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
TW591024B (en) * 2000-03-27 2004-06-11 Sankyo Lifetech Company Ltd An amide type triazole compound having antifungal activity
DE10129725A1 (de) * 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
US7049443B2 (en) 2001-07-12 2006-05-23 Pharmacia & Upjohn Company Amide-containing compound having improved solubility and method of improving the solubility of an amide-containing compound
JP3630326B2 (ja) * 2002-08-22 2005-03-16 三共株式会社 水溶性トリアゾール医薬組成物
US7265140B2 (en) * 2003-09-23 2007-09-04 Pfizer Inc Acyloxymethylcarbamate prodrugs of oxazolidinones
DE10355461A1 (de) * 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
DE102004002044A1 (de) * 2004-01-15 2005-08-04 Bayer Healthcare Ag Herstellverfahren
MXPA06013960A (es) * 2004-06-18 2007-03-15 Millennium Pharm Inc Inhibidores del factor xa.
WO2006017351A1 (fr) * 2004-07-12 2006-02-16 Xenoport, Inc. Promédicaments de propofol, leurs compositions et leur utilisation
DE102004062475A1 (de) * 2004-12-24 2006-07-06 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung
DE102005047558A1 (de) * 2005-10-04 2008-02-07 Bayer Healthcare Ag Kombinationstherapie substituierter Oxazolidinone zur Prophylaxe und Behandlung von cerebralen Durchblutungsstörungen
DE102006007146A1 (de) * 2006-02-16 2007-08-23 Bayer Healthcare Ag Aminoacyl-Prodrugs
DE102006025314A1 (de) * 2006-05-31 2007-12-06 Bayer Healthcare Ag Arylsubstituierte Heterozyklen und ihre Verwendung
DE102007028407A1 (de) * 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
DE102007028406A1 (de) * 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
DE102007028319A1 (de) * 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung

Also Published As

Publication number Publication date
AU2007287749B2 (en) 2013-09-12
US8362015B2 (en) 2013-01-29
CN101547921A (zh) 2009-09-30
CA2661414A1 (fr) 2008-02-28
WO2008022786A1 (fr) 2008-02-28
BRPI0715741A2 (pt) 2013-07-16
EP2084154A1 (fr) 2009-08-05
CA2661414C (fr) 2015-04-28
EP2084154B1 (fr) 2012-11-21
CN101547921B (zh) 2015-01-07
MX2009001977A (es) 2009-05-21
JP2010501504A (ja) 2010-01-21
ES2399069T3 (es) 2013-03-25
DE102006039589A1 (de) 2008-03-06
IL197079A0 (en) 2009-11-18
HK1137987A1 (en) 2010-08-13
US20100292230A1 (en) 2010-11-18
RU2009110246A (ru) 2010-09-27
AU2007287749A1 (en) 2008-02-28
KR20090057266A (ko) 2009-06-04
RU2456283C2 (ru) 2012-07-20
RU2456283C9 (ru) 2013-05-10
JP5352461B2 (ja) 2013-11-27

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