ZA200900071B - Non-nucleoside reverse transcriptase inhibitors - Google Patents
Non-nucleoside reverse transcriptase inhibitorsInfo
- Publication number
- ZA200900071B ZA200900071B ZA200900071A ZA200900071A ZA200900071B ZA 200900071 B ZA200900071 B ZA 200900071B ZA 200900071 A ZA200900071 A ZA 200900071A ZA 200900071 A ZA200900071 A ZA 200900071A ZA 200900071 B ZA200900071 B ZA 200900071B
- Authority
- ZA
- South Africa
- Prior art keywords
- reverse transcriptase
- transcriptase inhibitors
- nucleoside reverse
- nucleoside
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
- C07C311/46—Y being a hydrogen or a carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/51—Y being a hydrogen or a carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83248206P | 2006-07-21 | 2006-07-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200900071B true ZA200900071B (en) | 2010-01-27 |
Family
ID=38521766
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200900071A ZA200900071B (en) | 2006-07-21 | 2009-01-05 | Non-nucleoside reverse transcriptase inhibitors |
Country Status (16)
Country | Link |
---|---|
US (1) | US20080020981A1 (ja) |
EP (1) | EP2046731A1 (ja) |
JP (1) | JP2009544645A (ja) |
KR (1) | KR20090031584A (ja) |
CN (1) | CN101484418A (ja) |
AR (1) | AR061943A1 (ja) |
AU (1) | AU2007276180A1 (ja) |
BR (1) | BRPI0714509A2 (ja) |
CA (1) | CA2657723A1 (ja) |
CL (1) | CL2007002105A1 (ja) |
IL (1) | IL196144A0 (ja) |
MX (1) | MX2009000574A (ja) |
PE (1) | PE20080558A1 (ja) |
TW (1) | TW200812942A (ja) |
WO (1) | WO2008009613A1 (ja) |
ZA (1) | ZA200900071B (ja) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007045573A1 (en) * | 2005-10-19 | 2007-04-26 | F. Hoffmann-La Roche Ag | Phenyl-acetamide nnrt inhibitors |
BRPI0813404A2 (pt) * | 2007-06-22 | 2014-12-30 | Hoffmann La Roche | Derivados de uréia e carbamato como inibidores de transcriptase reversa de não-nucleosídeo |
CN102229547A (zh) * | 2011-04-20 | 2011-11-02 | 复旦大学 | 一种萘苯醚类苯磺酰胺衍生物及其制备方法和用途 |
CN102206177A (zh) * | 2011-04-20 | 2011-10-05 | 复旦大学 | 1-萘基苯甲酮衍生物及其制备方法和用途 |
MX2018012687A (es) | 2016-05-12 | 2019-01-31 | Res Triangle Inst | Fenitelaminas vinílogas como liberadores de neurotransmisores. |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7166736B2 (en) * | 2002-05-07 | 2007-01-23 | Supresta Llc | Neopentylglycol bis(diaryl phosphate) esters |
TW200423930A (en) * | 2003-02-18 | 2004-11-16 | Hoffmann La Roche | Non-nucleoside reverse transcriptase inhibitors |
JP4485520B2 (ja) * | 2003-03-24 | 2010-06-23 | エフ.ホフマン−ラ ロシュ アーゲー | 逆転写酵素阻害剤としてのベンジル−ピリダジノン類 |
TW200505441A (en) * | 2003-03-24 | 2005-02-16 | Hoffmann La Roche | Non-nucleoside reverse transcriptase inhibitorsⅠ |
US7220772B2 (en) * | 2003-09-05 | 2007-05-22 | Pfizer, Inc. | Pyrazole derivatives |
JP4627315B2 (ja) * | 2004-03-23 | 2011-02-09 | エフ.ホフマン−ラ ロシュ アーゲー | 非ヌクレオシド逆転写酵素阻害剤としてのベンジルピリダジノン誘導体 |
US7625949B2 (en) * | 2004-04-23 | 2009-12-01 | Roche Palo Alto Llc | Methods for treating retroviral infections |
EP1773790B1 (en) * | 2004-07-27 | 2012-08-15 | F.Hoffmann-La Roche Ag | Benzyltriazolone compounds as non-nucleoside reverse transcriptase inhibitors |
WO2006034583A1 (en) * | 2004-09-30 | 2006-04-06 | Boehringer Ingelheim International Gmbh & Co Kg | Alkynyl based dervatives of benzophenone as non-nucleoside reverse transcriptase inhibitors |
EP1831157A2 (en) * | 2004-12-22 | 2007-09-12 | Pfizer Limited | Nonnucleoside inhibitors of hiv-1 reverse transcriptase |
JP2008534456A (ja) * | 2005-03-24 | 2008-08-28 | エフ.ホフマン−ラ ロシュ アーゲー | ヘテロ環式逆転写酵素インヒビターとしての1,2,4−トリアゾール−5−オン化合物 |
AR057455A1 (es) * | 2005-07-22 | 2007-12-05 | Merck & Co Inc | Inhibidores de la transcriptasa reversa de vih y composicion farmaceutica |
ATE418545T1 (de) * | 2005-09-30 | 2009-01-15 | Hoffmann La Roche | Nnrt-inhibitoren |
WO2007045573A1 (en) * | 2005-10-19 | 2007-04-26 | F. Hoffmann-La Roche Ag | Phenyl-acetamide nnrt inhibitors |
EP1940782B1 (en) * | 2005-10-19 | 2009-03-11 | F.Hoffmann-La Roche Ag | N-phenyl phenylacetamide non-nucleoside reverse transcriptase inhibitors |
-
2007
- 2007-07-10 CL CL200702105A patent/CL2007002105A1/es unknown
- 2007-07-12 EP EP07787426A patent/EP2046731A1/en not_active Withdrawn
- 2007-07-12 MX MX2009000574A patent/MX2009000574A/es not_active Application Discontinuation
- 2007-07-12 CN CNA200780025636XA patent/CN101484418A/zh active Pending
- 2007-07-12 CA CA002657723A patent/CA2657723A1/en not_active Abandoned
- 2007-07-12 AU AU2007276180A patent/AU2007276180A1/en not_active Abandoned
- 2007-07-12 BR BRPI0714509-8A2A patent/BRPI0714509A2/pt not_active IP Right Cessation
- 2007-07-12 JP JP2009521203A patent/JP2009544645A/ja active Pending
- 2007-07-12 KR KR1020097001227A patent/KR20090031584A/ko not_active Application Discontinuation
- 2007-07-12 WO PCT/EP2007/057155 patent/WO2008009613A1/en active Application Filing
- 2007-07-18 TW TW096126195A patent/TW200812942A/zh unknown
- 2007-07-19 PE PE2007000940A patent/PE20080558A1/es not_active Application Discontinuation
- 2007-07-20 US US11/880,229 patent/US20080020981A1/en not_active Abandoned
- 2007-07-20 AR ARP070103236A patent/AR061943A1/es unknown
-
2008
- 2008-12-23 IL IL196144A patent/IL196144A0/en unknown
-
2009
- 2009-01-05 ZA ZA200900071A patent/ZA200900071B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
PE20080558A1 (es) | 2008-05-16 |
BRPI0714509A2 (pt) | 2014-04-08 |
TW200812942A (en) | 2008-03-16 |
EP2046731A1 (en) | 2009-04-15 |
AU2007276180A1 (en) | 2008-01-24 |
KR20090031584A (ko) | 2009-03-26 |
IL196144A0 (en) | 2009-09-22 |
CA2657723A1 (en) | 2008-01-24 |
WO2008009613A1 (en) | 2008-01-24 |
MX2009000574A (es) | 2009-01-27 |
CL2007002105A1 (es) | 2008-02-22 |
AR061943A1 (es) | 2008-10-01 |
US20080020981A1 (en) | 2008-01-24 |
CN101484418A (zh) | 2009-07-15 |
JP2009544645A (ja) | 2009-12-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL199103A0 (en) | Non-nucleoside reverse transcriptase inhibitors | |
IL196655A0 (en) | Non-nucleoside reverse transcriptase inhibitors | |
EP2076492A4 (en) | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | |
EP2217069A4 (en) | INHIBITORS OF NON-NUCLEOSIDE INHIBITORS OF THE REVERSE TRANSCRIPTASE | |
IL205386A0 (en) | Non - nucleoside reverse transcriptase inhibitors | |
IL200748A0 (en) | Non-nucleoside reverse transcriptse inhibitors | |
AP2514A (en) | HIV reverse transcriptase inhibitors | |
TWI372619B (en) | Non-nucleoside reverse transcriptase inhibitors | |
EP2220091A4 (en) | REVERSE transcriptase inhibitors | |
ZA201000023B (en) | Novel hiv reverse transcriptase inhibitors | |
ZA200803174B (en) | N-phenyl phenylacetamide non-nucleoside reverse transcriptase inhibitors | |
IL188615A0 (en) | Hiv reverse transcriptase inhibitors | |
PL2402319T3 (pl) | Inhibitory DGAT | |
HK1176601A1 (zh) | 抑制劑 | |
ZA200901073B (en) | Kinase inhibitor | |
DK2383271T3 (da) | Aminoquinoloner som GSK-3-inhibitorer | |
IL180495A0 (en) | Benzyltriazolone compounds as nin-nucleoside reverse transcriptase inhibitors | |
IL194494A0 (en) | Thiazolyldihydrocyclopentapyrazoles for use as pi3-kinase inhibitors | |
IL200886A0 (en) | Non-nucleoside reverse transcriptase inhibitors | |
ZA200900071B (en) | Non-nucleoside reverse transcriptase inhibitors | |
EP2177529A4 (en) | NEW DE-SECRETASE INHIBITOR | |
EP1899340A4 (en) | NON-NUCLEOSIDIC REVERSE TRANSCRIPTASE INHIBITORS | |
IL202143A0 (en) | Non-nucleoside reverse transcriptase inhibitors | |
EP2222662A4 (en) | INHIBITORS OF KYNURENINE AMINO TRANSFERASE | |
ZA200800185B (en) | Hiv reverse transcriptase inhibitors |