ZA200808017B - Tetrahydropyridothienopyrimidine compounds and methods of use thereof - Google Patents

Tetrahydropyridothienopyrimidine compounds and methods of use thereof

Info

Publication number
ZA200808017B
ZA200808017B ZA200808017A ZA200808017A ZA200808017B ZA 200808017 B ZA200808017 B ZA 200808017B ZA 200808017 A ZA200808017 A ZA 200808017A ZA 200808017 A ZA200808017 A ZA 200808017A ZA 200808017 B ZA200808017 B ZA 200808017B
Authority
ZA
South Africa
Prior art keywords
tetrahydropyridothienopyrimidine
compounds
methods
tetrahydropyridothienopyrimidine compounds
Prior art date
Application number
ZA200808017A
Other languages
English (en)
Inventor
Zhang Chengzhi
Sidhu Kanwar
Lobell Mario
Ladouceur Gaetan
Zhao Qian
Liu Zheng
Kristen M Allegue
Chetan P Darne
Newcom Jason
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of ZA200808017B publication Critical patent/ZA200808017B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
ZA200808017A 2006-03-20 2008-09-18 Tetrahydropyridothienopyrimidine compounds and methods of use thereof ZA200808017B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78414606P 2006-03-20 2006-03-20

Publications (1)

Publication Number Publication Date
ZA200808017B true ZA200808017B (en) 2009-11-25

Family

ID=38523058

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200808017A ZA200808017B (en) 2006-03-20 2008-09-18 Tetrahydropyridothienopyrimidine compounds and methods of use thereof

Country Status (29)

Country Link
US (1) US8501755B2 (es)
EP (1) EP2001890B1 (es)
JP (1) JP5282026B2 (es)
KR (1) KR20080110834A (es)
CN (1) CN101448840B (es)
AR (1) AR059901A1 (es)
AT (1) ATE495179T1 (es)
AU (1) AU2007227317A1 (es)
BR (1) BRPI0711045A2 (es)
CA (1) CA2647036C (es)
CR (1) CR10304A (es)
DE (1) DE602007011906D1 (es)
DO (1) DOP2007000053A (es)
EC (1) ECSP088749A (es)
ES (1) ES2357654T3 (es)
GT (1) GT200800187A (es)
IL (1) IL194028A0 (es)
MA (1) MA30351B1 (es)
MX (1) MX2008012006A (es)
NZ (1) NZ571326A (es)
PA (1) PA8719401A1 (es)
PE (1) PE20080144A1 (es)
RU (1) RU2008141239A (es)
SV (1) SV2008003032A (es)
TN (1) TNSN08370A1 (es)
TW (1) TW200804397A (es)
UY (1) UY30220A1 (es)
WO (1) WO2007109279A2 (es)
ZA (1) ZA200808017B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
JP5461402B2 (ja) * 2007-09-14 2014-04-02 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 置換三環式化合物およびその使用方法
BRPI0912267A2 (pt) 2008-05-23 2015-10-13 Amira Pharmaceuticals Inc sal farmaceuticamente aceitável, composição farmacêutica, artigo de fabricação, métodos para tratar asma, rinite alérgica, doença, lesões gástricas e dor, métodos para prevenir broncoconstrição e rinite alérgica, uso de um sal farmaceuticamente aceitável, e, processo para a preparação de um sal farmaceuticamente aceitável.
TWI385174B (zh) * 2008-11-10 2013-02-11 Nat Health Research Institutes 作為酪胺酸激酶抑制劑之稠合雙環及多環嘧啶化合物
EP2806876A4 (en) * 2012-01-25 2016-03-02 Proteostasis Therapeutics Inc COMPOUNDS ENHANCING THE ACTIVITY OF PROTEASOMES
WO2015181063A1 (en) * 2014-05-26 2015-12-03 Bayer Pharma Aktiengesellschaft Substituted tetrahydropyridothienopyrimidines
US10561749B2 (en) 2015-07-03 2020-02-18 Kyoto University Nuclear medicine diagnostic imaging agent
CR20180598A (es) 2016-06-22 2019-11-20 Univ Vanderbilt Moduladores alostéricos positivos del receptor muscarínico de acetilcolina m4
JP7099725B2 (ja) 2016-11-07 2022-07-12 ヴァンダービルト ユニヴァーシティ ムスカリン性アセチルコリンレセプターm4のポジティブアロステリック調節因子
CN109863139B (zh) 2016-11-07 2023-02-17 范德比尔特大学 毒蕈碱型乙酰胆碱受体m4的正向别构调节剂
MA46722A (fr) 2016-11-07 2019-09-11 Univ Vanderbilt Modulateurs allostériques positifs du récepteur muscarinique à l'acétylcholine m4
CN111406058A (zh) 2017-12-05 2020-07-10 范德比尔特大学 毒蕈碱型乙酰胆碱受体m4的正向别构调节剂
TW201930311A (zh) 2017-12-05 2019-08-01 泛德比爾特大學 蕈毒鹼型乙醯膽鹼受體m4之正向別構調節劑
EP3941905A1 (en) * 2019-03-19 2022-01-26 Suvalent Therapeutics, Inc. Sumo inhibitor compounds and uses thereof
KR20240044458A (ko) * 2021-08-05 2024-04-04 브리스톨-마이어스 스큅 컴퍼니 Her2 억제제로서 사용하기 위한 트리시클릭 융합된 피리미딘 화합물
CN114736154B (zh) * 2022-03-15 2023-07-21 安庆朗坤药业有限公司 N-(3-氯-4-(2-吡啶甲氧基)苯基)-2-氰基乙酰胺的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000059912A1 (fr) * 1999-03-30 2000-10-12 Nippon Soda Co., Ltd. Composes de thienopyrimidine et leurs sels, et procede de preparation desdits composes et sels
DE19944604A1 (de) 1999-09-17 2001-03-22 Merck Patent Gmbh Aminderivate
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
WO2003035653A1 (fr) * 2001-10-26 2003-05-01 Nippon Soda Co.,Ltd. Compose pyridothienopyrimidine et son sel
EP1651652B1 (en) * 2003-07-24 2006-12-27 Bayer Pharmaceuticals Corporation Substituted tetrahydrobenzothienopyrimidinamine compounds useful for treating hyper-proliferative disorders

Also Published As

Publication number Publication date
WO2007109279A3 (en) 2007-12-21
AU2007227317A1 (en) 2007-09-27
MA30351B1 (fr) 2009-04-01
UY30220A1 (es) 2007-10-31
RU2008141239A (ru) 2010-04-27
US8501755B2 (en) 2013-08-06
AR059901A1 (es) 2008-05-07
CN101448840A (zh) 2009-06-03
PE20080144A1 (es) 2008-04-06
KR20080110834A (ko) 2008-12-19
JP5282026B2 (ja) 2013-09-04
CA2647036C (en) 2015-06-23
DE602007011906D1 (de) 2011-02-24
ATE495179T1 (de) 2011-01-15
EP2001890A2 (en) 2008-12-17
PA8719401A1 (es) 2009-02-09
IL194028A0 (en) 2009-09-22
WO2007109279A2 (en) 2007-09-27
CR10304A (es) 2009-01-27
US20100298297A1 (en) 2010-11-25
CA2647036A1 (en) 2007-09-27
TNSN08370A1 (en) 2009-12-29
DOP2007000053A (es) 2007-09-30
CN101448840B (zh) 2011-12-14
SV2008003032A (es) 2009-11-26
NZ571326A (en) 2011-07-29
EP2001890B1 (en) 2011-01-12
JP2009530387A (ja) 2009-08-27
ECSP088749A (es) 2008-10-31
TW200804397A (en) 2008-01-16
GT200800187A (es) 2009-04-07
BRPI0711045A2 (pt) 2012-06-26
ES2357654T3 (es) 2011-04-28
MX2008012006A (es) 2008-10-03

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