ZA200806074B - Compounds for the treatment of inflammatory disorders - Google Patents
Compounds for the treatment of inflammatory disordersInfo
- Publication number
- ZA200806074B ZA200806074B ZA200806074A ZA200806074A ZA200806074B ZA 200806074 B ZA200806074 B ZA 200806074B ZA 200806074 A ZA200806074 A ZA 200806074A ZA 200806074 A ZA200806074 A ZA 200806074A ZA 200806074 B ZA200806074 B ZA 200806074B
- Authority
- ZA
- South Africa
- Prior art keywords
- compounds
- treatment
- inflammatory disorders
- disorders
- inflammatory
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 208000027866 inflammatory disease Diseases 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- C07D473/00—Heterocyclic compounds containing purine ring systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
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- C—CHEMISTRY; METALLURGY
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
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- C07D495/04—Ortho-condensed systems
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Addiction (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Transplantation (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/333,663 US7504424B2 (en) | 2004-07-16 | 2006-01-17 | Compounds for the treatment of inflammatory disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200806074B true ZA200806074B (en) | 2009-05-27 |
Family
ID=38169339
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200806074A ZA200806074B (en) | 2006-01-17 | 2008-07-11 | Compounds for the treatment of inflammatory disorders |
Country Status (17)
Country | Link |
---|---|
US (2) | US7504424B2 (xx) |
EP (1) | EP1976849B1 (xx) |
JP (1) | JP2009523795A (xx) |
KR (1) | KR20080093048A (xx) |
CN (1) | CN101410388A (xx) |
AR (1) | AR058901A1 (xx) |
AU (1) | AU2007207671A1 (xx) |
BR (1) | BRPI0707152A2 (xx) |
CA (1) | CA2637385A1 (xx) |
EC (1) | ECSP088627A (xx) |
IL (1) | IL192692A0 (xx) |
NO (1) | NO20083561L (xx) |
PE (1) | PE20070852A1 (xx) |
RU (1) | RU2008133388A (xx) |
TW (1) | TW200736248A (xx) |
WO (1) | WO2007084415A2 (xx) |
ZA (1) | ZA200806074B (xx) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE478864T1 (de) | 2004-07-16 | 2010-09-15 | Schering Corp | Hydantoinderivate zur behandlung von entzündlichen erkrankungen |
US7488745B2 (en) * | 2004-07-16 | 2009-02-10 | Schering Corporation | Compounds for the treatment of inflammatory disorders |
US7504424B2 (en) | 2004-07-16 | 2009-03-17 | Schering Corporation | Compounds for the treatment of inflammatory disorders |
ATE518853T1 (de) * | 2005-08-12 | 2011-08-15 | Schering Corp | Verbindungen zur behandlung entzündlicher erkrankungen |
PE20071240A1 (es) * | 2006-01-17 | 2008-01-14 | Schering Corp | Compuestos derivados de hidantoina para el tratamiento de trastornos inflamatorios |
JP2010502617A (ja) | 2006-08-31 | 2010-01-28 | シェーリング コーポレイション | 抗菌物質として有用なヒダントイン誘導体 |
EP2331528B1 (en) | 2008-09-24 | 2020-05-27 | Merck Sharp & Dohme Corp. | Compounds for the treatment of inflammatory disorders |
EP2346857B1 (en) * | 2008-09-24 | 2019-11-27 | Merck Sharp & Dohme Corp. | Compounds for the treatment of inflammatory disorders |
WO2010054279A1 (en) | 2008-11-10 | 2010-05-14 | Schering Corporation | Compounds for the treatment of inflammatory disorders |
US8569336B2 (en) | 2008-11-10 | 2013-10-29 | Ling Tong | Compounds for the treatment of inflammatory disorders |
CA2804918C (en) | 2010-07-08 | 2018-03-06 | Kaken Pharmaceutical Co., Ltd. | N-hydroxyformamide derivative and medicament containing same |
KR101848077B1 (ko) * | 2010-11-13 | 2018-04-11 | 이노크린 파마슈티컬즈, 인크. | 금속효소 억제제 화합물 |
CN106831541B (zh) | 2011-11-18 | 2019-09-06 | 赫普泰雅治疗有限公司 | 毒蕈碱性m1受体激动剂 |
PL2789607T3 (pl) * | 2011-12-09 | 2018-08-31 | Kaken Pharmaceutical Co., Ltd. | Pochodna pirydonu i lek zawierający tę pochodną |
EP2791121B1 (en) * | 2011-12-12 | 2016-08-03 | Allergan, Inc. | Benzisothiazol-3(1h)-one-5-sulfonyl derivatives as chemokine receptor modulators |
ES2655030T3 (es) | 2012-11-19 | 2018-02-16 | Novartis Ag | Compuestos y composiciones para el tratamiento de enfermedades parasitarias |
US8871754B2 (en) | 2012-11-19 | 2014-10-28 | Irm Llc | Compounds and compositions for the treatment of parasitic diseases |
JP6478923B2 (ja) | 2013-02-07 | 2019-03-06 | ヘプタレス セラピューティクス リミテッドHeptares Therapeutics Limited | ムスカリンm4受容体アゴニストとしてのピペリジン−1−イル及びアゼピン−1−イルカルボキシレート |
RU2668072C2 (ru) | 2013-06-07 | 2018-09-27 | Какен Фармасьютикал Ко., Лтд. | (+)-5-(3,4-дифторфенил)-5-[(3-метил-2-оксопиридин-1(2h)-ил)метил]имидазолидин-2,4-дион, а также лекарственное средство, включающее его в свой состав |
JO3501B1 (ar) | 2014-12-22 | 2020-07-05 | Servier Lab | مشتقات 5-{(بيبرازين - 1-يل)-3-أوكسو - بروبيل}- إيميدازوليدين-2، 4 - دايون كمثبطات ل adamts لمعالجة هشاشة العظام) |
GB201513743D0 (en) | 2015-08-03 | 2015-09-16 | Heptares Therapeutics Ltd | Muscarinic agonists |
SI3344248T1 (sl) | 2015-09-02 | 2022-07-29 | Trevena, Inc. | 6-členske aza-heterociklične spojine za modulacijo, ki vsebujejo delta-opioidne receptorje, metode uporabe in izdelave |
GB201617454D0 (en) | 2016-10-14 | 2016-11-30 | Heptares Therapeutics Limited | Pharmaceutical compounds |
CA3052479A1 (en) | 2017-02-17 | 2018-08-23 | Trevena, Inc. | 7-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same |
BR112019016827A2 (pt) | 2017-02-17 | 2020-04-07 | Trevena Inc | compostos moduladores de receptor delta-opioide contendo aza-heterocíclico com 5 membros, métodos de uso e produção dos mesmos |
GB201810239D0 (en) | 2018-06-22 | 2018-08-08 | Heptares Therapeutics Ltd | Pharmaceutical compounds |
GB201819960D0 (en) | 2018-12-07 | 2019-01-23 | Heptares Therapeutics Ltd | Pharmaceutical compounds |
GB202020191D0 (en) | 2020-12-18 | 2021-02-03 | Heptares Therapeutics Ltd | Pharmaceutical compounds |
WO2021011720A2 (en) * | 2019-07-18 | 2021-01-21 | Avidence Therapeutics, Inc. | Anti-osteoarthritis compounds and related compositions and methods |
Family Cites Families (17)
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US6228869B1 (en) * | 1996-10-16 | 2001-05-08 | American Cyanamid Company | Ortho-sulfonamido bicyclic hydroxamic acids as matrix metalloproteinase and TACE inhibitors |
US6677355B1 (en) * | 1999-08-18 | 2004-01-13 | Warner-Lambert Company | Hydroxamic acid compounds useful as matrix metalloproteinase inhibitors |
AU2001250850A1 (en) * | 2000-03-17 | 2001-10-03 | Dupont Pharmaceuticals Company | Beta-amino acid derivatives as inhibitors of matrix metalloproteases and tnf-alpha |
BR0208105A (pt) | 2001-03-15 | 2004-03-09 | Astrazeneca Ab | Inibidores de metaloproteinase |
DE60234028D1 (de) | 2001-05-25 | 2009-11-26 | Bristol Myers Squibb Co | Hydantion-derivate als hemmer von matrix-metalloproteinasen |
AU2002346729A1 (en) | 2001-12-20 | 2003-07-09 | Bristol-Myers Squibb Company | Barbituric acid derivatives as inhibitors of tnf-$g(a) converting enzyme (tace) and/or matrix metalloproteinases |
US7294624B2 (en) | 2001-12-20 | 2007-11-13 | Bristol Myers Squibb Company | Barbituric acid derivatives as inhibitors of TNF-α converting enzyme (TACE) and/or matrix metalloproteinases |
AU2003261319A1 (en) | 2002-08-01 | 2004-02-23 | Bristol-Myers Squibb Company | Hydantoin derivatives as inhibitors of matrix metalloproteinases and/or tnf-alpha converting enzyme |
GB0221246D0 (en) | 2002-09-13 | 2002-10-23 | Astrazeneca Ab | Compounds |
GB0221250D0 (en) | 2002-09-13 | 2002-10-23 | Astrazeneca Ab | Compounds |
WO2004033632A2 (en) * | 2002-10-04 | 2004-04-22 | Bristol-Myers Squibb Company | Hydantoin derivatives as inhibitors of matrix metalloproteinases and/or tnf-alpha converting enzyme (tace) |
DE60329326D1 (de) | 2002-12-19 | 2009-10-29 | Vertex Pharma | Tace inhibitoren |
US7504424B2 (en) | 2004-07-16 | 2009-03-17 | Schering Corporation | Compounds for the treatment of inflammatory disorders |
US7488745B2 (en) * | 2004-07-16 | 2009-02-10 | Schering Corporation | Compounds for the treatment of inflammatory disorders |
ATE478864T1 (de) * | 2004-07-16 | 2010-09-15 | Schering Corp | Hydantoinderivate zur behandlung von entzündlichen erkrankungen |
PE20071240A1 (es) * | 2006-01-17 | 2008-01-14 | Schering Corp | Compuestos derivados de hidantoina para el tratamiento de trastornos inflamatorios |
JP2010502617A (ja) * | 2006-08-31 | 2010-01-28 | シェーリング コーポレイション | 抗菌物質として有用なヒダントイン誘導体 |
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2006
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2007
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- 2007-01-16 RU RU2008133388/04A patent/RU2008133388A/ru not_active Application Discontinuation
- 2007-01-16 AU AU2007207671A patent/AU2007207671A1/en not_active Abandoned
- 2007-01-16 CN CNA2007800091460A patent/CN101410388A/zh active Pending
- 2007-01-16 JP JP2008551299A patent/JP2009523795A/ja not_active Withdrawn
- 2007-01-16 CA CA002637385A patent/CA2637385A1/en not_active Abandoned
- 2007-01-16 TW TW096101543A patent/TW200736248A/zh unknown
- 2007-01-16 AR ARP070100180A patent/AR058901A1/es not_active Application Discontinuation
- 2007-01-16 WO PCT/US2007/000930 patent/WO2007084415A2/en active Application Filing
- 2007-01-16 KR KR1020087019865A patent/KR20080093048A/ko not_active Application Discontinuation
- 2007-01-16 EP EP07709799.6A patent/EP1976849B1/en active Active
- 2007-01-16 BR BRPI0707152-3A patent/BRPI0707152A2/pt not_active IP Right Cessation
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2008
- 2008-07-08 IL IL192692A patent/IL192692A0/en unknown
- 2008-07-11 ZA ZA200806074A patent/ZA200806074B/xx unknown
- 2008-07-16 EC EC2008008627A patent/ECSP088627A/es unknown
- 2008-08-15 NO NO20083561A patent/NO20083561L/no not_active Application Discontinuation
- 2008-12-18 US US12/338,425 patent/US7687527B2/en active Active
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AR058901A1 (es) | 2008-02-27 |
BRPI0707152A2 (pt) | 2011-04-19 |
RU2008133388A (ru) | 2010-02-27 |
WO2007084415A3 (en) | 2007-10-18 |
US20060276506A1 (en) | 2006-12-07 |
KR20080093048A (ko) | 2008-10-17 |
US7687527B2 (en) | 2010-03-30 |
US20090170875A1 (en) | 2009-07-02 |
JP2009523795A (ja) | 2009-06-25 |
EP1976849B1 (en) | 2016-03-09 |
AU2007207671A1 (en) | 2007-07-26 |
PE20070852A1 (es) | 2007-09-24 |
CA2637385A1 (en) | 2007-07-26 |
WO2007084415A2 (en) | 2007-07-26 |
US7504424B2 (en) | 2009-03-17 |
CN101410388A (zh) | 2009-04-15 |
ECSP088627A (es) | 2008-08-29 |
TW200736248A (en) | 2007-10-01 |
NO20083561L (no) | 2008-10-16 |
IL192692A0 (en) | 2009-08-03 |
EP1976849A2 (en) | 2008-10-08 |
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