ZA200802990B - Process for the synthesis of compounds for selectin inhibition - Google Patents

Process for the synthesis of compounds for selectin inhibition

Info

Publication number
ZA200802990B
ZA200802990B ZA200802990A ZA200802990A ZA200802990B ZA 200802990 B ZA200802990 B ZA 200802990B ZA 200802990 A ZA200802990 A ZA 200802990A ZA 200802990 A ZA200802990 A ZA 200802990A ZA 200802990 B ZA200802990 B ZA 200802990B
Authority
ZA
South Africa
Prior art keywords
synthesis
compounds
selectin inhibition
selectin
inhibition
Prior art date
Application number
ZA200802990A
Other languages
English (en)
Inventor
Wang Youchu
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of ZA200802990B publication Critical patent/ZA200802990B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200802990A 2005-10-05 2008-04-04 Process for the synthesis of compounds for selectin inhibition ZA200802990B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72373405P 2005-10-05 2005-10-05

Publications (1)

Publication Number Publication Date
ZA200802990B true ZA200802990B (en) 2008-12-31

Family

ID=37672216

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200802990A ZA200802990B (en) 2005-10-05 2008-04-04 Process for the synthesis of compounds for selectin inhibition

Country Status (19)

Country Link
US (1) US20070082923A1 (zh)
EP (1) EP1931638A1 (zh)
JP (1) JP2009511488A (zh)
KR (1) KR20080053389A (zh)
CN (1) CN101277936A (zh)
AR (1) AR058079A1 (zh)
AU (1) AU2006302375A1 (zh)
BR (1) BRPI0616906A2 (zh)
CA (1) CA2624552A1 (zh)
CR (1) CR9854A (zh)
EC (1) ECSP088340A (zh)
GT (1) GT200600447A (zh)
IL (1) IL190435A0 (zh)
NO (1) NO20081548L (zh)
PE (1) PE20070590A1 (zh)
RU (1) RU2008112191A (zh)
TW (1) TW200738639A (zh)
WO (1) WO2007044475A1 (zh)
ZA (1) ZA200802990B (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090127183A (ko) * 2007-03-30 2009-12-09 와이어쓰 퀴놀린 유도체, 및 이를 포함하는 셀렉틴 억제용 제약 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6239280B1 (en) * 1999-06-30 2001-05-29 Merck & Co., Inc. Process for synthesizing biaryl inhibitors of farnesyl-protein transferase
PA8616901A1 (es) * 2003-11-10 2005-05-24 Wyeth Corp Metodos y composiciones para la inhibicion de selectina

Also Published As

Publication number Publication date
TW200738639A (en) 2007-10-16
BRPI0616906A2 (pt) 2011-07-05
AR058079A1 (es) 2008-01-23
NO20081548L (no) 2008-04-28
CA2624552A1 (en) 2007-04-19
WO2007044475A1 (en) 2007-04-19
ECSP088340A (es) 2008-06-30
CR9854A (es) 2008-05-21
CN101277936A (zh) 2008-10-01
AU2006302375A1 (en) 2007-04-19
JP2009511488A (ja) 2009-03-19
IL190435A0 (en) 2008-11-03
EP1931638A1 (en) 2008-06-18
GT200600447A (es) 2007-05-08
US20070082923A1 (en) 2007-04-12
KR20080053389A (ko) 2008-06-12
RU2008112191A (ru) 2009-11-10
PE20070590A1 (es) 2007-07-11

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