ZA200710764B - Nanoparticulate acetaminophen formulations - Google Patents
Nanoparticulate acetaminophen formulationsInfo
- Publication number
- ZA200710764B ZA200710764B ZA200710764A ZA200710764A ZA200710764B ZA 200710764 B ZA200710764 B ZA 200710764B ZA 200710764 A ZA200710764 A ZA 200710764A ZA 200710764 A ZA200710764 A ZA 200710764A ZA 200710764 B ZA200710764 B ZA 200710764B
- Authority
- ZA
- South Africa
- Prior art keywords
- acetaminophen formulations
- nanoparticulate acetaminophen
- nanoparticulate
- formulations
- acetaminophen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68711405P | 2005-06-03 | 2005-06-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200710764B true ZA200710764B (en) | 2009-08-26 |
Family
ID=38006352
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200710764A ZA200710764B (en) | 2005-06-03 | 2007-12-11 | Nanoparticulate acetaminophen formulations |
Country Status (13)
Country | Link |
---|---|
US (1) | US20060292214A1 (fr) |
EP (1) | EP1901728A2 (fr) |
JP (1) | JP2008542396A (fr) |
KR (1) | KR20080017065A (fr) |
CN (1) | CN101262860A (fr) |
AU (1) | AU2006309295B2 (fr) |
BR (1) | BRPI0611075A2 (fr) |
CA (1) | CA2610480A1 (fr) |
EA (1) | EA015336B1 (fr) |
IL (1) | IL187842A0 (fr) |
NO (1) | NO20076692L (fr) |
WO (1) | WO2007053197A2 (fr) |
ZA (1) | ZA200710764B (fr) |
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MX2010009990A (es) | 2008-03-11 | 2010-12-15 | Depomed Inc | Formas de dosificación gástricas retentivas de liberación prolongada que comprenden combinaciones de un analgésico no opioide y un analgésico opioide. |
WO2009117410A2 (fr) * | 2008-03-17 | 2009-09-24 | Board Of Regents, The University Of Texas System | Formation de particules nanostructurées de médicaments médiocrement solubles dans l'eau et récupération par des techniques mécaniques |
WO2009143558A1 (fr) * | 2008-05-26 | 2009-12-03 | Silphion Pty Limited | Formulations injectables |
EP2243477A1 (fr) | 2009-04-22 | 2010-10-27 | Fresenius Kabi Deutschland GmbH | Paracétamol destiné à l'administration parentérale |
UA111138C2 (uk) * | 2009-04-24 | 2016-04-11 | Айсьютіка Пті Лтд | Спосіб одержання композиції твердого біологічно активного матеріалу |
US20100316725A1 (en) | 2009-05-27 | 2010-12-16 | Elan Pharma International Ltd. | Reduction of flake-like aggregation in nanoparticulate active agent compositions |
US8597681B2 (en) | 2009-12-22 | 2013-12-03 | Mallinckrodt Llc | Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans |
US9198861B2 (en) | 2009-12-22 | 2015-12-01 | Mallinckrodt Llc | Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans |
CN101978953A (zh) * | 2010-10-11 | 2011-02-23 | 上海交通大学 | 基于易吸湿性辅料的固体制剂 |
US8900635B2 (en) | 2010-11-15 | 2014-12-02 | Humanetics Corporation | Nanoparticle isoflavone compositions and methods of making and using the same |
US9050335B1 (en) | 2011-05-17 | 2015-06-09 | Mallinckrodt Llc | Pharmaceutical compositions for extended release of oxycodone and acetaminophen resulting in a quick onset and prolonged period of analgesia |
US8858963B1 (en) | 2011-05-17 | 2014-10-14 | Mallinckrodt Llc | Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia |
US8741885B1 (en) | 2011-05-17 | 2014-06-03 | Mallinckrodt Llc | Gastric retentive extended release pharmaceutical compositions |
EP2765999A4 (fr) * | 2011-10-14 | 2015-04-01 | Purdue Research Foundation | Unité à multiples feuilles pouvant être ingérée à fonctions et combinaisons prédéterminées |
RU2471491C1 (ru) * | 2011-10-19 | 2013-01-10 | Станислав Анатольевич Кедик | Применение сополимера на основе n-винилпирролидона в качестве средства, потенцирующего анальгетический эффект морфина гидрохлорида |
CN105050585A (zh) * | 2013-03-04 | 2015-11-11 | Vtv治疗有限责任公司 | 稳定的葡萄糖激酶活化剂组合物 |
CN103211759B (zh) * | 2013-03-28 | 2015-07-08 | 中国人民解放军军事医学科学院毒物药物研究所 | 葛根素纳米晶药用组合物及其制备方法 |
GB201308933D0 (en) * | 2013-05-17 | 2013-07-03 | Diurnal Ltd | Paediatric composition |
WO2015023675A2 (fr) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Comprimé extrudé anti-abus à libération immédiate |
US9084726B2 (en) * | 2013-11-26 | 2015-07-21 | Humanetics Corporation | Suspension compositions of physiologically active phenolic compounds and methods of making and using the same |
US10172797B2 (en) | 2013-12-17 | 2019-01-08 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
CA2950734C (fr) | 2014-06-11 | 2022-07-26 | Mallinckrodt Llc | Compositions sechees par pulverisation presentant differents profils de dissolution et procedes pour les preparer |
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WO2016064873A1 (fr) | 2014-10-20 | 2016-04-28 | Pharmaceutical Manufacturing Research Services, Inc. | Forme galénique anti-abus de remplissage de liquide à libération prolongée |
CN107669634A (zh) * | 2016-09-30 | 2018-02-09 | 青岛大学 | 一种对乙酰氨基酚口腔喷雾剂及其制备方法 |
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AU2003297151A1 (en) * | 2002-12-17 | 2004-07-22 | Elan Pharma International Ltd. | Milling microgram quantities of nanoparticulate candidate compounds |
US20040208833A1 (en) * | 2003-02-04 | 2004-10-21 | Elan Pharma International Ltd. | Novel fluticasone formulations |
US8512727B2 (en) * | 2003-03-03 | 2013-08-20 | Alkermes Pharma Ireland Limited | Nanoparticulate meloxicam formulations |
US7767118B2 (en) * | 2003-06-03 | 2010-08-03 | Ferro Corporation | Nanoparticles from supercritical fluid antisolvent process using particle growth and agglomeration retardants |
US20040265378A1 (en) * | 2003-06-25 | 2004-12-30 | Yingxu Peng | Method and compositions for producing granules containing high concentrations of biologically active substances |
US20050042177A1 (en) * | 2003-07-23 | 2005-02-24 | Elan Pharma International Ltd. | Novel compositions of sildenafil free base |
ATE415946T1 (de) * | 2003-08-08 | 2008-12-15 | Elan Pharma Int Ltd | Neue metaxalon-zusammensetzungen |
ES2366646T3 (es) * | 2003-11-05 | 2011-10-24 | Elan Pharma International Limited | Composiciones en forma de nanopartículas que tienen un péptido como estabilizante superficial. |
US20050147664A1 (en) * | 2003-11-13 | 2005-07-07 | Elan Pharma International Ltd. | Compositions comprising antibodies and methods of using the same for targeting nanoparticulate active agent delivery |
EP1761250A4 (fr) * | 2004-05-28 | 2007-05-09 | Imaginot Pty Ltd | Systeme d'administration par voie orale |
-
2006
- 2006-06-05 US US11/446,564 patent/US20060292214A1/en not_active Abandoned
- 2006-06-05 BR BRPI0611075-4A patent/BRPI0611075A2/pt not_active Application Discontinuation
- 2006-06-05 KR KR1020077030960A patent/KR20080017065A/ko not_active Application Discontinuation
- 2006-06-05 AU AU2006309295A patent/AU2006309295B2/en not_active Ceased
- 2006-06-05 WO PCT/US2006/021656 patent/WO2007053197A2/fr active Application Filing
- 2006-06-05 JP JP2008514948A patent/JP2008542396A/ja active Pending
- 2006-06-05 CN CNA2006800283199A patent/CN101262860A/zh active Pending
- 2006-06-05 CA CA002610480A patent/CA2610480A1/fr not_active Abandoned
- 2006-06-05 EA EA200702638A patent/EA015336B1/ru not_active IP Right Cessation
- 2006-06-05 EP EP06844132A patent/EP1901728A2/fr not_active Withdrawn
-
2007
- 2007-12-03 IL IL187842A patent/IL187842A0/en unknown
- 2007-12-11 ZA ZA200710764A patent/ZA200710764B/xx unknown
- 2007-12-28 NO NO20076692A patent/NO20076692L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2006309295A1 (en) | 2007-05-10 |
CN101262860A (zh) | 2008-09-10 |
BRPI0611075A2 (pt) | 2010-08-03 |
JP2008542396A (ja) | 2008-11-27 |
US20060292214A1 (en) | 2006-12-28 |
EP1901728A2 (fr) | 2008-03-26 |
EA015336B1 (ru) | 2011-06-30 |
CA2610480A1 (fr) | 2007-05-10 |
WO2007053197A2 (fr) | 2007-05-10 |
IL187842A0 (en) | 2008-03-20 |
EA200702638A1 (ru) | 2008-04-28 |
AU2006309295B2 (en) | 2012-04-26 |
WO2007053197A3 (fr) | 2007-11-29 |
KR20080017065A (ko) | 2008-02-25 |
NO20076692L (no) | 2008-02-28 |
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