ZA200707486B - Use of 2-(2-nitro-4-trifluoromenthylbenzoyl)-1,3- cyclohexanedione in the treatment of parkinson's disease - Google Patents
Use of 2-(2-nitro-4-trifluoromenthylbenzoyl)-1,3- cyclohexanedione in the treatment of parkinson's diseaseInfo
- Publication number
- ZA200707486B ZA200707486B ZA200707486A ZA200707486A ZA200707486B ZA 200707486 B ZA200707486 B ZA 200707486B ZA 200707486 A ZA200707486 A ZA 200707486A ZA 200707486 A ZA200707486 A ZA 200707486A ZA 200707486 B ZA200707486 B ZA 200707486B
- Authority
- ZA
- South Africa
- Prior art keywords
- disease
- parkinson
- treatment
- cyclohexanedione
- nitro
- Prior art date
Links
- 208000018737 Parkinson disease Diseases 0.000 title abstract 3
- 229940125782 compound 2 Drugs 0.000 abstract 2
- 230000004770 neurodegeneration Effects 0.000 abstract 2
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- OUBCNLGXQFSTLU-UHFFFAOYSA-N nitisinone Chemical compound [O-][N+](=O)C1=CC(C(F)(F)F)=CC=C1C(=O)C1C(=O)CCCC1=O OUBCNLGXQFSTLU-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0504103.3A GB0504103D0 (en) | 2005-02-28 | 2005-02-28 | Novel method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200707486B true ZA200707486B (en) | 2009-02-25 |
Family
ID=34430351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200707486A ZA200707486B (en) | 2005-02-28 | 2006-02-27 | Use of 2-(2-nitro-4-trifluoromenthylbenzoyl)-1,3- cyclohexanedione in the treatment of parkinson's disease |
Country Status (17)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2748599T3 (es) | 2007-08-27 | 2020-03-17 | Dart Neuroscience Cayman Ltd | Compuestos terapéuticos de isoxazol |
| CA2709784A1 (en) * | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| CN102395595A (zh) * | 2008-11-06 | 2012-03-28 | 生物链接治疗股份有限公司 | 不宁腿综合症和睡眠障碍的治疗 |
| JP6038132B2 (ja) | 2011-06-23 | 2016-12-07 | スウェディッシュ オーファン バイオビトラム インターナショナル アクチエボラグ | ニチシノンを含む液体薬学的組成物 |
| CN103622942A (zh) * | 2013-11-04 | 2014-03-12 | 江苏大学 | 左旋多巴/卡比多巴复方缓释混悬剂及其制备方法 |
| WO2017017165A1 (en) * | 2015-07-29 | 2017-02-02 | Takeda Gmbh | Pde4 inhibitor for the treatment of diabetic nephropathy |
| ITUB20160650A1 (it) | 2016-02-11 | 2017-08-11 | Dipharma S A | Formulazioni farmaceutiche solide stabili contenenti 2-(2-nitro-4-trifluorometilbenzoil)-1,3-cicloesandione |
| US9783485B1 (en) | 2016-11-30 | 2017-10-10 | Dipharma S.A. | Crystalline inhibitor of 4-hydroxyphenylpyruvate dioxygenase, and a process of synthesis and crystallization thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4780127A (en) * | 1982-03-25 | 1988-10-25 | Stauffer Chemical Company | Certain 2-(substituted benzoyl)-1,3-cyclohexanediones and their use as herbicides |
| US5092919A (en) * | 1991-01-15 | 1992-03-03 | Imperial Chemical Industries Plc | Certain 2-(2'-methyl-3',4'-trisubstituted benzoyl)-1,3-cyclohexanediones |
| AU672361B2 (en) * | 1991-06-24 | 1996-10-03 | Swedish Orphan Biovitrum International Ab | Use of 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione in the treatment of tyrosinaemia and pharmaceutical compositions |
| FR2777781B1 (fr) * | 1998-04-24 | 2004-04-09 | Rhone Poulenc Rorer Sa | Associations riluzole et l-dopa pour le traitement de la maladie de parkinson |
| US20050288187A1 (en) * | 2002-07-03 | 2005-12-29 | Hanauske-Abel Hartmut M | Inhibitor development for 4-hydroxyphenylpyruvate dioxygenase, employing tyrosinemia 1 as a model for human diseases mediated by 2-oxoacid utilizing dioxygenases |
| US20060166972A1 (en) * | 2003-07-11 | 2006-07-27 | Conn P J | Treatment of movement disorders with a metabotropic glutamate 4 receptor positive allosteric modulator |
| EP2233136A1 (en) * | 2006-08-18 | 2010-09-29 | Syngenta Limited | Use of HPPD Inhibitors in the Treatment of Depression and/or Withdrawal Symptoms Associated with Addictive Drugs |
| CN102395595A (zh) * | 2008-11-06 | 2012-03-28 | 生物链接治疗股份有限公司 | 不宁腿综合症和睡眠障碍的治疗 |
-
2005
- 2005-02-28 GB GBGB0504103.3A patent/GB0504103D0/en not_active Ceased
-
2006
- 2006-02-27 JP JP2007557572A patent/JP2008531665A/ja active Pending
- 2006-02-27 PT PT06709910T patent/PT1853241E/pt unknown
- 2006-02-27 MX MX2007010480A patent/MX2007010480A/es not_active Application Discontinuation
- 2006-02-27 DK DK06709910.1T patent/DK1853241T3/da active
- 2006-02-27 CN CN2006800133878A patent/CN101163466B/zh not_active Expired - Fee Related
- 2006-02-27 BR BRPI0609177-6A patent/BRPI0609177A2/pt not_active IP Right Cessation
- 2006-02-27 WO PCT/GB2006/000684 patent/WO2006090177A1/en not_active Ceased
- 2006-02-27 AT AT06709910T patent/ATE524171T1/de active
- 2006-02-27 ZA ZA200707486A patent/ZA200707486B/xx unknown
- 2006-02-27 AU AU2006217650A patent/AU2006217650B2/en not_active Ceased
- 2006-02-27 US US12/090,645 patent/US20090326072A1/en not_active Abandoned
- 2006-02-27 ES ES06709910T patent/ES2374761T3/es active Active
- 2006-02-27 CA CA002598517A patent/CA2598517A1/en not_active Abandoned
- 2006-02-27 EP EP06709910A patent/EP1853241B1/en active Active
- 2006-02-27 RU RU2007131934/15A patent/RU2420272C2/ru not_active IP Right Cessation
-
2007
- 2007-08-21 IL IL185410A patent/IL185410A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2420272C2 (ru) | 2011-06-10 |
| CA2598517A1 (en) | 2006-08-31 |
| EP1853241A1 (en) | 2007-11-14 |
| JP2008531665A (ja) | 2008-08-14 |
| WO2006090177A1 (en) | 2006-08-31 |
| ES2374761T3 (es) | 2012-02-21 |
| CN101163466B (zh) | 2011-12-07 |
| BRPI0609177A2 (pt) | 2010-02-23 |
| EP1853241B1 (en) | 2011-09-14 |
| CN101163466A (zh) | 2008-04-16 |
| AU2006217650A1 (en) | 2006-08-31 |
| AU2006217650B2 (en) | 2011-06-09 |
| RU2007131934A (ru) | 2009-02-27 |
| US20090326072A1 (en) | 2009-12-31 |
| PT1853241E (pt) | 2012-01-11 |
| IL185410A0 (en) | 2008-08-07 |
| DK1853241T3 (da) | 2012-01-16 |
| GB0504103D0 (en) | 2005-04-06 |
| ATE524171T1 (de) | 2011-09-15 |
| HK1110211A1 (en) | 2008-07-11 |
| MX2007010480A (es) | 2008-02-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2009006742A (es) | Inhibidores acilaminopirazoles como fgfr. | |
| PT1696905E (pt) | 2-aminotetralinas substituídas para o tratamento preventivo da doença de parkinson | |
| TW200635582A (en) | Medicaments for the treatment or prevention of fibrotic diseases | |
| IL185410A0 (en) | Use of 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione in the treatment of parkinson's disease | |
| TW200728307A (en) | Novel spirochromanone derivatives | |
| EP1940373B8 (en) | 1-fluoro-1-deoxy-scyllo-inositol for the treatment of alzheimer's disease | |
| MY145439A (en) | Use of flibanserin for the treatment of pre-menopausal sexual desire disorders | |
| WO2009025785A3 (en) | Cb2 receptor ligands for the treatment of pain | |
| MY151295A (en) | Pyrimidyl indoline compound | |
| WO2009071690A3 (de) | 5,6-disubstituierte oxindol-derivate und ihre verwendung zur behandlung von vasopressin-abhängigen erkrankungen | |
| DK1670903T3 (da) | Behandling af neurodegenerative sygdomme | |
| PT1778837E (pt) | Tratamento de doenças neurodegenerativas por utilização de inibidores de scd4 | |
| WO2007131907A3 (en) | 1h-indol-5-yl-piperazin-1-yl-methanone derivatives | |
| TW200716547A (en) | Piperidin-4-yl-amide derivatives | |
| MX2008001546A (es) | 3,11b-cis-dihidrotetrabenazina para el tratamiento de una enfermedad proliferativa o una inflamacion. | |
| UA97348C2 (en) | HETEROCYCLIC NF-kB INHIBITORS | |
| DE602006010738D1 (de) | Pyrroloä2,3-cüpyridinderivate | |
| TW200716152A (en) | Substituted 1,2-ethylendiamines, medicaments comprising said compound, their use and their method of manufacture | |
| TW200635595A (en) | Medicaments for the treatment of prevention of fibrotic diseases | |
| ZA200700945B (en) | Derivatives of 1-phenylalkanecarboxylic acids for the treatment of neurodegenerative diseases | |
| DE602007008947D1 (en) | 4,5,6,7-tetrahydrothienoä2,3-cüpyridine als h3-modulatoren | |
| ZA200800999B (en) | Use of N-dibenz (b,f)oxepin-10-ylmethyl)-N-methyl-N-prop-2-ynylamine (omigapil) for the prophylaxis and/or treatment of muscular dystrophy | |
| WO2008014232A3 (en) | Pharmaceutical formulations for the treatment of alzheimer's disease | |
| HK1164058A (en) | Specific diarylhydantoin and diarylthiohydantoin compounds | |
| UA87292C2 (ru) | Применение сирамезина для лечения злокачественных опухолей |