ZA200704740B - Two-piece capsule comprising a preliminary closure for accommodating pharmaceutical preparations for powder inhalers - Google Patents
Two-piece capsule comprising a preliminary closure for accommodating pharmaceutical preparations for powder inhalers Download PDFInfo
- Publication number
- ZA200704740B ZA200704740B ZA200704740A ZA200704740A ZA200704740B ZA 200704740 B ZA200704740 B ZA 200704740B ZA 200704740 A ZA200704740 A ZA 200704740A ZA 200704740 A ZA200704740 A ZA 200704740A ZA 200704740 B ZA200704740 B ZA 200704740B
- Authority
- ZA
- South Africa
- Prior art keywords
- capsule
- amino
- quinazoline
- raised
- chloro
- Prior art date
Links
- 239000002775 capsule Substances 0.000 title claims abstract description 176
- 239000000843 powder Substances 0.000 title claims abstract description 18
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract description 6
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- IMBFFWDWIAWOLR-UHFFFAOYSA-N n-[4-(3-chloro-4-fluoroanilino)-7-cyclopentyloxyquinazolin-6-yl]-4-[2-methoxyethyl(methyl)amino]but-2-enamide Chemical compound N1=CN=C2C=C(OC3CCCC3)C(NC(=O)C=CCN(C)CCOC)=CC2=C1NC1=CC=C(F)C(Cl)=C1 IMBFFWDWIAWOLR-UHFFFAOYSA-N 0.000 description 1
- PLPRGLOFPNJOTN-UHFFFAOYSA-N narcotine Natural products COc1ccc2C(OC(=O)c2c1OC)C3Cc4c(CN3C)cc5OCOc5c4OC PLPRGLOFPNJOTN-UHFFFAOYSA-N 0.000 description 1
- 229960004398 nedocromil Drugs 0.000 description 1
- RQTOOFIXOKYGAN-UHFFFAOYSA-N nedocromil Chemical compound CCN1C(C(O)=O)=CC(=O)C2=C1C(CCC)=C1OC(C(O)=O)=CC(=O)C1=C2 RQTOOFIXOKYGAN-UHFFFAOYSA-N 0.000 description 1
- 229960004708 noscapine Drugs 0.000 description 1
- 229960002657 orciprenaline Drugs 0.000 description 1
- NVOYVOBDTVTBDX-PMEUIYRNSA-N oxitropium Chemical class CC[N+]1(C)[C@H]2C[C@@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)C1=CC=CC=C1 NVOYVOBDTVTBDX-PMEUIYRNSA-N 0.000 description 1
- 229960001609 oxitropium bromide Drugs 0.000 description 1
- LCELQERNWLBPSY-KHSTUMNDSA-M oxitropium bromide Chemical compound [Br-].C1([C@@H](CO)C(=O)O[C@H]2C[C@@H]3[N+]([C@H](C2)[C@@H]2[C@H]3O2)(C)CC)=CC=CC=C1 LCELQERNWLBPSY-KHSTUMNDSA-M 0.000 description 1
- 229960001972 panitumumab Drugs 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 150000002960 penicillins Chemical class 0.000 description 1
- XDRYMKDFEDOLFX-UHFFFAOYSA-N pentamidine Chemical compound C1=CC(C(=N)N)=CC=C1OCCCCCOC1=CC=C(C(N)=N)C=C1 XDRYMKDFEDOLFX-UHFFFAOYSA-N 0.000 description 1
- 229960004448 pentamidine Drugs 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 229960001802 phenylephrine Drugs 0.000 description 1
- SONNWYBIRXJNDC-VIFPVBQESA-N phenylephrine Chemical compound CNC[C@H](O)C1=CC=CC(O)=C1 SONNWYBIRXJNDC-VIFPVBQESA-N 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000002587 phosphodiesterase IV inhibitor Substances 0.000 description 1
- 229960005414 pirbuterol Drugs 0.000 description 1
- 229960004583 pranlukast Drugs 0.000 description 1
- UAJUXJSXCLUTNU-UHFFFAOYSA-N pranlukast Chemical compound C=1C=C(OCCCCC=2C=CC=CC=2)C=CC=1C(=O)NC(C=1)=CC=C(C(C=2)=O)C=1OC=2C=1N=NNN=1 UAJUXJSXCLUTNU-UHFFFAOYSA-N 0.000 description 1
- 229960005205 prednisolone Drugs 0.000 description 1
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 description 1
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- 229960002288 procaterol Drugs 0.000 description 1
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- 230000001681 protective effect Effects 0.000 description 1
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- WVLAAKXASPCBGT-UHFFFAOYSA-N reproterol Chemical compound C1=2C(=O)N(C)C(=O)N(C)C=2N=CN1CCCNCC(O)C1=CC(O)=CC(O)=C1 WVLAAKXASPCBGT-UHFFFAOYSA-N 0.000 description 1
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- MNDBXUUTURYVHR-UHFFFAOYSA-N roflumilast Chemical compound FC(F)OC1=CC=C(C(=O)NC=2C(=CN=CC=2Cl)Cl)C=C1OCC1CC1 MNDBXUUTURYVHR-UHFFFAOYSA-N 0.000 description 1
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- 229960002052 salbutamol Drugs 0.000 description 1
- 229960004017 salmeterol Drugs 0.000 description 1
- 101150115956 slc25a26 gene Proteins 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 238000005476 soldering Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
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- 125000000446 sulfanediyl group Chemical group *S* 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 229960000195 terbutaline Drugs 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
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- 229960000278 theophylline Drugs 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 238000003856 thermoforming Methods 0.000 description 1
- 229940110309 tiotropium Drugs 0.000 description 1
- 229960000257 tiotropium bromide Drugs 0.000 description 1
- 229940040693 tiotropium bromide monohydrate Drugs 0.000 description 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-M toluene-4-sulfonate Chemical compound CC1=CC=C(S([O-])(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-M 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
- A61M15/0025—Mouthpieces therefor with caps
- A61M15/0026—Hinged caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/0041—Details of the piercing or cutting means with movable piercing or cutting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Closures For Containers (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005001332A DE102005001332A1 (de) | 2005-01-11 | 2005-01-11 | Zweiteilige Kapsel mit Vorverschluss zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200704740B true ZA200704740B (en) | 2008-07-30 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200704740A ZA200704740B (en) | 2005-01-11 | 2007-06-18 | Two-piece capsule comprising a preliminary closure for accommodating pharmaceutical preparations for powder inhalers |
Country Status (26)
Country | Link |
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US (1) | US8662076B2 (pt) |
EP (1) | EP1838293B1 (pt) |
JP (1) | JP2008526411A (pt) |
KR (1) | KR101298510B1 (pt) |
CN (1) | CN101115470B (pt) |
AT (1) | ATE411009T1 (pt) |
AU (1) | AU2006205848B2 (pt) |
BR (1) | BRPI0606312A2 (pt) |
CA (1) | CA2593204C (pt) |
CY (1) | CY1108732T1 (pt) |
DE (2) | DE102005001332A1 (pt) |
DK (1) | DK1838293T3 (pt) |
EA (1) | EA011678B1 (pt) |
ES (1) | ES2316042T3 (pt) |
HR (1) | HRP20080645T3 (pt) |
IL (1) | IL184495A (pt) |
MX (1) | MX2007008364A (pt) |
NO (1) | NO20073193L (pt) |
NZ (1) | NZ560305A (pt) |
PL (1) | PL1838293T3 (pt) |
PT (1) | PT1838293E (pt) |
RS (1) | RS51114B (pt) |
SI (1) | SI1838293T1 (pt) |
UA (1) | UA87022C2 (pt) |
WO (1) | WO2006074982A2 (pt) |
ZA (1) | ZA200704740B (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
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JP6037315B2 (ja) | 2011-05-27 | 2016-12-07 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 吸入器及び吸入器用カプセル |
EP2614848B1 (de) | 2012-01-13 | 2020-07-01 | Boehringer Ingelheim International GmbH | Inhalator und Kapsel für einen Inhalator |
WO2013174752A2 (de) | 2012-05-21 | 2013-11-28 | Boehringer Ingelheim International Gmbh | System aus inhalator und kapsel |
US20140004482A1 (en) * | 2012-06-29 | 2014-01-02 | Christos Angeletakis | Methods, compositions and apparatus for applying an agent to a dental substrate and uses thereof |
CA173518S (en) | 2016-02-08 | 2017-09-01 | Nicoventures Holdings Ltd | Cartridge for an electronic cigarette |
GB201605102D0 (en) | 2016-03-24 | 2016-05-11 | Nicoventures Holdings Ltd | Mechanical connector for electronic vapour provision system |
GB201605100D0 (en) | 2016-03-24 | 2016-05-11 | Nicoventures Holdings Ltd | Vapour provision system |
GB201605101D0 (en) | 2016-03-24 | 2016-05-11 | Nicoventures Holdings Ltd | Electronic vapour provision system |
GB201605105D0 (en) | 2016-03-24 | 2016-05-11 | Nicoventures Holdings Ltd | Vapour provision apparatus |
US11524823B2 (en) | 2016-07-22 | 2022-12-13 | Nicoventures Trading Limited | Case for a vapor provision device |
CA3236068A1 (en) * | 2017-07-10 | 2019-01-17 | Gel Cap Technologies, LLC | Dual release dosage form capsule and methods, devices and systems for making same |
ES2924175T3 (es) * | 2018-03-28 | 2022-10-05 | Hoefliger Harro Verpackung | Manguito para cápsula para cápsulas ensamblables y sistema de manguitos |
EP3861974B1 (de) * | 2020-02-07 | 2023-06-07 | Harro Höfliger Verpackungsmaschinen GmbH | Kapselverschliesseinrichtung zum verschliessen zweiteiliger kapseln |
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IT941426B (it) | 1971-07-17 | 1973-03-01 | Isf Spa | Inalatore a camera di turbinio per sostanze medicamentose polveriformi |
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-
2005
- 2005-01-11 DE DE102005001332A patent/DE102005001332A1/de not_active Withdrawn
-
2006
- 2006-01-06 PT PT06700744T patent/PT1838293E/pt unknown
- 2006-01-06 NZ NZ560305A patent/NZ560305A/en not_active IP Right Cessation
- 2006-01-06 DE DE502006001826T patent/DE502006001826D1/de active Active
- 2006-01-06 UA UAA200708833A patent/UA87022C2/ru unknown
- 2006-01-06 RS RSP-2008/0499A patent/RS51114B/sr unknown
- 2006-01-06 CA CA2593204A patent/CA2593204C/en not_active Expired - Fee Related
- 2006-01-06 WO PCT/EP2006/050064 patent/WO2006074982A2/de active Application Filing
- 2006-01-06 JP JP2007550780A patent/JP2008526411A/ja active Pending
- 2006-01-06 KR KR1020077018454A patent/KR101298510B1/ko not_active IP Right Cessation
- 2006-01-06 AT AT06700744T patent/ATE411009T1/de active
- 2006-01-06 EP EP06700744A patent/EP1838293B1/de active Active
- 2006-01-06 MX MX2007008364A patent/MX2007008364A/es active IP Right Grant
- 2006-01-06 BR BRPI0606312-8A patent/BRPI0606312A2/pt not_active IP Right Cessation
- 2006-01-06 ES ES06700744T patent/ES2316042T3/es active Active
- 2006-01-06 DK DK06700744T patent/DK1838293T3/da active
- 2006-01-06 US US11/327,050 patent/US8662076B2/en active Active
- 2006-01-06 CN CN2006800046583A patent/CN101115470B/zh not_active Expired - Fee Related
- 2006-01-06 SI SI200630164T patent/SI1838293T1/sl unknown
- 2006-01-06 AU AU2006205848A patent/AU2006205848B2/en not_active Ceased
- 2006-01-06 PL PL06700744T patent/PL1838293T3/pl unknown
- 2006-01-06 EA EA200701401A patent/EA011678B1/ru not_active IP Right Cessation
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2007
- 2007-06-18 ZA ZA200704740A patent/ZA200704740B/en unknown
- 2007-06-22 NO NO20073193A patent/NO20073193L/no not_active Application Discontinuation
- 2007-07-09 IL IL184495A patent/IL184495A/en not_active IP Right Cessation
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2008
- 2008-12-10 HR HR20080645T patent/HRP20080645T3/xx unknown
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2009
- 2009-01-14 CY CY20091100031T patent/CY1108732T1/el unknown
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