ZA200702527B - Methods for antibody library screening - Google Patents
Methods for antibody library screeningInfo
- Publication number
- ZA200702527B ZA200702527B ZA200702527A ZA200702527A ZA200702527B ZA 200702527 B ZA200702527 B ZA 200702527B ZA 200702527 A ZA200702527 A ZA 200702527A ZA 200702527 A ZA200702527 A ZA 200702527A ZA 200702527 B ZA200702527 B ZA 200702527B
- Authority
- ZA
- South Africa
- Prior art keywords
- target entities
- members
- library
- methods
- antibody library
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000012216 screening Methods 0.000 title abstract 2
- 239000012074 organic phase Substances 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1086—Preparation or screening of expression libraries, e.g. reporter assays
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Semiconductor Lasers (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0422431.7A GB0422431D0 (en) | 2004-10-08 | 2004-10-08 | Method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200702527B true ZA200702527B (en) | 2008-11-26 |
Family
ID=33443626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200702527A ZA200702527B (en) | 2004-10-08 | 2005-10-07 | Methods for antibody library screening |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20090081190A1 (pt) |
| EP (1) | EP1800133B1 (pt) |
| JP (1) | JP4564062B2 (pt) |
| CN (1) | CN101052879B (pt) |
| AT (1) | ATE495446T1 (pt) |
| AU (1) | AU2005291012B2 (pt) |
| BR (1) | BRPI0516546A (pt) |
| CA (1) | CA2580080C (pt) |
| DE (1) | DE602005025901D1 (pt) |
| DK (1) | DK1800133T3 (pt) |
| ES (1) | ES2359724T3 (pt) |
| GB (1) | GB0422431D0 (pt) |
| HK (1) | HK1105450A1 (pt) |
| HR (1) | HRP20110234T1 (pt) |
| IL (1) | IL181927A (pt) |
| NO (1) | NO20071618L (pt) |
| NZ (1) | NZ554076A (pt) |
| PL (1) | PL1800133T3 (pt) |
| RU (1) | RU2402777C2 (pt) |
| SI (1) | SI1800133T1 (pt) |
| WO (1) | WO2006038022A1 (pt) |
| ZA (1) | ZA200702527B (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6126773B2 (ja) * | 2007-09-04 | 2017-05-10 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 癌のターゲッティングおよび検出のための高親和性抗前立腺幹細胞抗原（ｐｓｃａ）抗体 |
| US9079942B2 (en) * | 2009-02-09 | 2015-07-14 | Epitomics, Inc. | CDR-anchored amplification method |
| US20100317539A1 (en) * | 2009-06-12 | 2010-12-16 | Guo-Liang Yu | Library of Engineered-Antibody Producing Cells |
| US8293483B2 (en) * | 2009-09-11 | 2012-10-23 | Epitomics, Inc. | Method for identifying lineage-related antibodies |
| WO2012082237A1 (en) | 2010-10-26 | 2012-06-21 | Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University | Immunization with amyloid-beta oligomers |
| GB201116364D0 (en) * | 2011-09-22 | 2011-11-02 | Bioinvent Int Ab | Screening methods and uses thereof |
| EP2817625A2 (en) * | 2012-02-23 | 2014-12-31 | Stage Cell Therapeutics GmbH | Chromatographic isolation of cells and other complex biological materials |
| WO2014087191A1 (en) * | 2012-12-04 | 2014-06-12 | Scinopharm Taiwan Ltd. | Method for selecting a pool of molecules |
| RU2560699C2 (ru) * | 2013-08-02 | 2015-08-20 | федеральное государственное автономное образовательное учреждение высшего профессионального образования "Национальный исследовательский ядерный университет МИФИ" (НИЯУ МИФИ) | Способ создания наноразмерной диагностической метки на основе конъюгатов наночастиц и однодоменных антител |
| GB201420852D0 (en) * | 2014-11-24 | 2015-01-07 | Genevillage Kft | Method |
| RU2618872C1 (ru) * | 2015-12-09 | 2017-05-11 | Федеральное бюджетное учреждение науки Государственный научный центр прикладной микробиологии и биотехнологии (ФБУН ГНЦ ПМБ) | Способ направленного истощения олигонуклеотидных библиотек для снижения неспецифической адсорбции при твердофазной селекции аптамеров на основе нуклеиновых кислот |
| US10557216B2 (en) * | 2018-04-24 | 2020-02-11 | Inscripta, Inc. | Automated instrumentation for production of T-cell receptor peptide libraries |
| KR102301987B1 (ko) * | 2019-11-14 | 2021-09-13 | 연세대학교 산학협력단 | 항체 선별 방법, 박테리아 오염 진단 방법 및 박테리아 오염 진단 키트 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5565332A (en) * | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| US5492807A (en) * | 1993-11-19 | 1996-02-20 | Santi; Daniel V. | Method of obtaining diagnostic reagents, assays and therapeutics based on clinical manifestations of a disease |
| US6255455B1 (en) * | 1996-10-11 | 2001-07-03 | The Trustees Of The University Of Pennsylvania | Rh(D)-binding proteins and magnetically activated cell sorting method for production thereof |
| TW585921B (en) * | 1997-07-10 | 2004-05-01 | Res Dev Foundation | Species specific monoclonal antibodies and phage displayed Fab and scFV fragments for fragments for targeted destruction of imported fire ants |
| US6235686B1 (en) * | 2000-08-16 | 2001-05-22 | R.T. Vanderbilt Company, Inc. | Lubricating compositions containing aromatized 1,2-dihydro-2,2,4-trimethylquinoline polymers |
| US20040170955A1 (en) * | 2000-09-08 | 2004-09-02 | Wadih Arap | Human and mouse targeting peptides identified by phage display |
| JP2004515751A (ja) * | 2000-09-08 | 2004-05-27 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | インビトロターゲティングのための方法および組成物 |
| US7420030B2 (en) * | 2000-09-08 | 2008-09-02 | The Board Of Regents Of The University Of Texas System | Aminopeptidase A (APA) targeting peptides for the treatment of cancer |
| US20040048243A1 (en) * | 2001-09-07 | 2004-03-11 | Wadih Arap | Methods and compositions for in vitro targeting |
-
2004
- 2004-10-08 GB GBGB0422431.7A patent/GB0422431D0/en not_active Ceased
-
2005
- 2005-10-07 CA CA2580080A patent/CA2580080C/en not_active Expired - Fee Related
- 2005-10-07 AT AT05791017T patent/ATE495446T1/de active
- 2005-10-07 DE DE602005025901T patent/DE602005025901D1/de active Active
- 2005-10-07 CN CN2005800341433A patent/CN101052879B/zh not_active Expired - Fee Related
- 2005-10-07 EP EP05791017A patent/EP1800133B1/en active Active
- 2005-10-07 WO PCT/GB2005/003866 patent/WO2006038022A1/en active Application Filing
- 2005-10-07 BR BRPI0516546-6A patent/BRPI0516546A/pt not_active Application Discontinuation
- 2005-10-07 RU RU2007117144/10A patent/RU2402777C2/ru not_active IP Right Cessation
- 2005-10-07 NZ NZ554076A patent/NZ554076A/en unknown
- 2005-10-07 ZA ZA200702527A patent/ZA200702527B/xx unknown
- 2005-10-07 US US11/664,844 patent/US20090081190A1/en not_active Abandoned
- 2005-10-07 AU AU2005291012A patent/AU2005291012B2/en not_active Ceased
- 2005-10-07 SI SI200531268T patent/SI1800133T1/sl unknown
- 2005-10-07 DK DK05791017.6T patent/DK1800133T3/da active
- 2005-10-07 ES ES05791017T patent/ES2359724T3/es active Active
- 2005-10-07 PL PL05791017T patent/PL1800133T3/pl unknown
- 2005-10-07 JP JP2007535243A patent/JP4564062B2/ja not_active Expired - Fee Related
-
2007
- 2007-03-14 IL IL181927A patent/IL181927A/en not_active IP Right Cessation
- 2007-03-27 NO NO20071618A patent/NO20071618L/no not_active Application Discontinuation
- 2007-12-17 HK HK07113708.9A patent/HK1105450A1/xx not_active IP Right Cessation
-
2011
- 2011-04-01 HR HR20110234T patent/HRP20110234T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE495446T1 (de) | 2011-01-15 |
| CA2580080A1 (en) | 2006-04-13 |
| JP4564062B2 (ja) | 2010-10-20 |
| HRP20110234T1 (hr) | 2011-05-31 |
| WO2006038022A1 (en) | 2006-04-13 |
| ES2359724T3 (es) | 2011-05-26 |
| CN101052879A (zh) | 2007-10-10 |
| PL1800133T3 (pl) | 2011-06-30 |
| SI1800133T1 (sl) | 2011-06-30 |
| BRPI0516546A (pt) | 2008-09-09 |
| DK1800133T3 (da) | 2011-03-28 |
| JP2008516220A (ja) | 2008-05-15 |
| RU2402777C2 (ru) | 2010-10-27 |
| DE602005025901D1 (de) | 2011-02-24 |
| US20090081190A1 (en) | 2009-03-26 |
| CN101052879B (zh) | 2012-07-25 |
| IL181927A0 (en) | 2007-07-04 |
| RU2007117144A (ru) | 2008-11-20 |
| EP1800133A1 (en) | 2007-06-27 |
| AU2005291012B2 (en) | 2011-04-14 |
| GB0422431D0 (en) | 2004-11-10 |
| AU2005291012A1 (en) | 2006-04-13 |
| NO20071618L (no) | 2007-06-27 |
| IL181927A (en) | 2011-09-27 |
| CA2580080C (en) | 2012-09-18 |
| HK1105450A1 (en) | 2008-02-15 |
| NZ554076A (en) | 2009-12-24 |
| EP1800133B1 (en) | 2011-01-12 |
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