ZA200701900B - Tablets with site and time-controlled gastrointestinal release of active ingredient - Google Patents
Tablets with site and time-controlled gastrointestinal release of active ingredient Download PDFInfo
- Publication number
- ZA200701900B ZA200701900B ZA200701900A ZA200701900A ZA200701900B ZA 200701900 B ZA200701900 B ZA 200701900B ZA 200701900 A ZA200701900 A ZA 200701900A ZA 200701900 A ZA200701900 A ZA 200701900A ZA 200701900 B ZA200701900 B ZA 200701900B
- Authority
- ZA
- South Africa
- Prior art keywords
- active ingredient
- tablet
- release
- coating
- corticosteroid
- Prior art date
Links
- 239000004480 active ingredient Substances 0.000 title claims description 127
- 230000002496 gastric effect Effects 0.000 title claims description 14
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- 229960004618 prednisone Drugs 0.000 claims description 84
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- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 claims description 26
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Inorganic Chemistry (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004043863A DE102004043863A1 (de) | 2004-09-10 | 2004-09-10 | Tabletten mit orts- und zeitgesteuerter Wirkstofffreisetzung im Gastrointestinum |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200701900B true ZA200701900B (en) | 2008-07-30 |
Family
ID=35276479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200701900A ZA200701900B (en) | 2004-09-10 | 2007-03-05 | Tablets with site and time-controlled gastrointestinal release of active ingredient |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20060057200A1 (ja) |
| EP (1) | EP2386295A3 (ja) |
| JP (1) | JP2010047607A (ja) |
| KR (1) | KR20110126757A (ja) |
| CN (2) | CN103284971B (ja) |
| BR (1) | BRPI0515345A (ja) |
| DE (1) | DE102004043863A1 (ja) |
| HK (2) | HK1110509A1 (ja) |
| IL (1) | IL181680A (ja) |
| MX (1) | MX2007002898A (ja) |
| RU (2) | RU2435568C2 (ja) |
| SG (1) | SG155908A1 (ja) |
| ZA (1) | ZA200701900B (ja) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE251449T1 (de) | 1999-06-14 | 2003-10-15 | Cosmo Spa | Geschmacksmaskierte orale pharmazeutische zusammensetzungen mit kontrollierter abgabe |
| US8895064B2 (en) | 1999-06-14 | 2014-11-25 | Cosmo Technologies Limited | Controlled release and taste masking oral pharmaceutical composition |
| ES2335008T3 (es) * | 2003-04-24 | 2010-03-18 | Jagotec Ag | Comprimido con nucleo coloreado. |
| AU2004231362B2 (en) | 2003-04-24 | 2009-11-12 | Jagotec Ag | Delayed release tablet with defined core geometry |
| WO2006027266A1 (en) * | 2004-09-10 | 2006-03-16 | Nitec Pharma Ag | Tablets with site time-controlled gastrointestinal release of active ingredient |
| DE102004043863A1 (de) * | 2004-09-10 | 2006-03-16 | Nitec Pharma Ag | Tabletten mit orts- und zeitgesteuerter Wirkstofffreisetzung im Gastrointestinum |
| DK1836665T3 (da) | 2004-11-19 | 2013-04-15 | Glaxosmithkline Llc | Fremgangsmåde til specialtilpasset afgivelse af medikamentkombinationsprodukter med variabel dosis til individualisering af terapier |
| ES2400446T5 (es) | 2006-08-03 | 2017-03-13 | Horizon Pharma Ag | Tratamiento con glucocorticoides de liberación retardada de una enfermedad reumática |
| EP2391369A1 (en) * | 2009-01-26 | 2011-12-07 | Nitec Pharma AG | Delayed-release glucocorticoid treatment of asthma |
| NZ582836A (en) * | 2009-01-30 | 2011-06-30 | Nitec Pharma Ag | Delayed-release glucocorticoid treatment of rheumatoid arthritis by improving signs and symptoms, showing major or complete clinical response and by preventing from joint damage |
| US8945616B2 (en) * | 2009-02-17 | 2015-02-03 | Mylan Pharmaceuticals Inc. | Controlled release budesonide minitablets |
| US8945615B2 (en) * | 2009-02-17 | 2015-02-03 | Mylan Pharmaceuticals Inc. | Controlled release budesonide minitablets |
| CN102218071A (zh) * | 2010-04-06 | 2011-10-19 | 上海安瀚特生物医药技术有限公司 | 一种微粉化地夫可特口服制剂及其制备方法 |
| WO2013030726A1 (en) * | 2011-08-26 | 2013-03-07 | Wockhardt Limited | Programmed drug delivery |
| US10154964B2 (en) | 2011-09-07 | 2018-12-18 | Cosmo Technologies Limited | Controlled release and taste masking oral pharmaceutical composition |
| CN103690545A (zh) * | 2013-11-27 | 2014-04-02 | 河南中帅医药科技股份有限公司 | 口服泼尼松择时释放制剂及其制备方法 |
| US11896719B2 (en) | 2022-01-24 | 2024-02-13 | Calliditas Therapeutics Ab | Pharmaceutical compositions |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1230576B (it) | 1988-10-20 | 1991-10-28 | Angeli Inst Spa | Formulazioni farmaceutiche per via orale a liberazione selettiva nel colon |
| JP2558396B2 (ja) | 1990-06-28 | 1996-11-27 | 田辺製薬株式会社 | 放出制御型製剤 |
| WO1994008589A1 (en) * | 1992-10-09 | 1994-04-28 | The Board Of Trustees Of The Leland Stanford Junior University | Treatment of systemic lupus erythematosus with dehydroepiandrosterone |
| US5464633A (en) | 1994-05-24 | 1995-11-07 | Jagotec Ag | Pharmaceutical tablets releasing the active substance after a definite period of time |
| US5811388A (en) * | 1995-06-07 | 1998-09-22 | Cibus Pharmaceutical, Inc. | Delivery of drugs to the lower GI tract |
| IT1282576B1 (it) * | 1996-02-06 | 1998-03-31 | Jagotec Ag | Compressa farmaceutica atta a cedere la sostanza attiva in tempi successivi e predeterminabili |
| HRP970493A2 (en) | 1996-09-23 | 1998-08-31 | Wienman E. Phlips | Oral delayed immediate release medical formulation and method for preparing the same |
| US5792476A (en) | 1996-12-19 | 1998-08-11 | Abigo Medical Ab | Sustained release glucocorticoid pharmaceutical composition |
| US5788987A (en) * | 1997-01-29 | 1998-08-04 | Poli Industria Chimica Spa | Methods for treating early morning pathologies |
| CA2327685C (en) | 1998-04-03 | 2008-11-18 | Bm Research A/S | Controlled release composition |
| GB9905898D0 (en) | 1999-03-15 | 1999-05-05 | Darwin Discovery Ltd | Controlled-dose formulation |
| JP2001010950A (ja) * | 1999-06-29 | 2001-01-16 | Taiyo Yakuhin Kogyo Kk | 安定で良好な薬物放出を有する医薬組成物 |
| EP1074249A1 (en) | 1999-07-27 | 2001-02-07 | Jagotec Ag | A pharmaceutical tablet system for releasing at least one active substance during a release period subsequent to a no-release period |
| DE10012555A1 (de) * | 2000-03-15 | 2001-09-20 | Merck Patent Gmbh | Glucocorticoide in einer Modified Release-Formulierung |
| US20020028240A1 (en) * | 2000-04-17 | 2002-03-07 | Toyohiro Sawada | Timed-release compression-coated solid composition for oral administration |
| AU2001247887A1 (en) | 2000-04-19 | 2001-11-07 | Eurand America Inc. | Dual mechanism timed release dosage forms for low dose drugs |
| US6620439B1 (en) | 2000-10-03 | 2003-09-16 | Atul M. Mehta | Chrono delivery formulations and method of use thereof |
| CA2440641A1 (en) * | 2001-03-13 | 2002-09-19 | Anand R. Baichwal | Chronotherapeutic dosage forms containing glucocorticosteroid |
| JPWO2003075919A1 (ja) * | 2002-03-14 | 2005-06-30 | 第一サントリーファーマ株式会社 | 塩酸ピルジカイニド含有錠剤（乾式） |
| AU2004231362B2 (en) | 2003-04-24 | 2009-11-12 | Jagotec Ag | Delayed release tablet with defined core geometry |
| ES2335008T3 (es) * | 2003-04-24 | 2010-03-18 | Jagotec Ag | Comprimido con nucleo coloreado. |
| US20050118267A1 (en) * | 2003-09-19 | 2005-06-02 | Penwest Pharmaceuticals Co. | Chronotherapeutic dosage forms |
| DE102004043863A1 (de) * | 2004-09-10 | 2006-03-16 | Nitec Pharma Ag | Tabletten mit orts- und zeitgesteuerter Wirkstofffreisetzung im Gastrointestinum |
| WO2006027266A1 (en) * | 2004-09-10 | 2006-03-16 | Nitec Pharma Ag | Tablets with site time-controlled gastrointestinal release of active ingredient |
-
2004
- 2004-09-10 DE DE102004043863A patent/DE102004043863A1/de not_active Ceased
-
2005
- 2005-09-01 US US11/216,469 patent/US20060057200A1/en not_active Abandoned
- 2005-09-09 MX MX2007002898A patent/MX2007002898A/es active IP Right Grant
- 2005-09-09 RU RU2007113168/15A patent/RU2435568C2/ru active
- 2005-09-09 RU RU2011119347/15A patent/RU2577164C2/ru active
- 2005-09-09 KR KR1020117024027A patent/KR20110126757A/ko not_active Application Discontinuation
- 2005-09-09 EP EP11156296A patent/EP2386295A3/en not_active Withdrawn
- 2005-09-09 SG SG200906036-9A patent/SG155908A1/en unknown
- 2005-09-09 CN CN201310037597.2A patent/CN103284971B/zh active Active
- 2005-09-09 BR BRPI0515345-0A patent/BRPI0515345A/pt not_active Application Discontinuation
- 2005-09-09 CN CN2005800342686A patent/CN101035517B/zh active Active
-
2007
- 2007-03-01 IL IL181680A patent/IL181680A/en active IP Right Grant
- 2007-03-05 ZA ZA200701900A patent/ZA200701900B/en unknown
-
2008
- 2008-02-05 HK HK08101360.2A patent/HK1110509A1/xx unknown
-
2009
- 2009-11-27 JP JP2009269373A patent/JP2010047607A/ja not_active Withdrawn
-
2012
- 2012-03-15 US US13/421,135 patent/US20120213910A1/en not_active Abandoned
-
2014
- 2014-03-11 HK HK14102428.2A patent/HK1189346A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101035517A (zh) | 2007-09-12 |
| MX2007002898A (es) | 2007-06-15 |
| CN103284971A (zh) | 2013-09-11 |
| CN101035517B (zh) | 2013-03-13 |
| DE102004043863A1 (de) | 2006-03-16 |
| EP2386295A3 (en) | 2012-04-25 |
| CN103284971B (zh) | 2016-05-11 |
| EP2386295A2 (en) | 2011-11-16 |
| RU2007113168A (ru) | 2008-10-27 |
| RU2435568C2 (ru) | 2011-12-10 |
| JP2010047607A (ja) | 2010-03-04 |
| HK1189346A1 (zh) | 2014-06-06 |
| IL181680A0 (en) | 2007-07-04 |
| SG155908A1 (en) | 2009-10-29 |
| KR20110126757A (ko) | 2011-11-23 |
| IL181680A (en) | 2015-04-30 |
| RU2011119347A (ru) | 2012-11-20 |
| RU2577164C2 (ru) | 2016-03-10 |
| HK1110509A1 (en) | 2008-07-18 |
| BRPI0515345A (pt) | 2008-07-22 |
| US20060057200A1 (en) | 2006-03-16 |
| US20120213910A1 (en) | 2012-08-23 |
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