ZA200608552B - Anti-microbial activity of biologically stabilized silver nano particles - Google Patents
Anti-microbial activity of biologically stabilized silver nano particles Download PDFInfo
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- ZA200608552B ZA200608552B ZA200608552A ZA200608552A ZA200608552B ZA 200608552 B ZA200608552 B ZA 200608552B ZA 200608552 A ZA200608552 A ZA 200608552A ZA 200608552 A ZA200608552 A ZA 200608552A ZA 200608552 B ZA200608552 B ZA 200608552B
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- silver
- nano particles
- silver nano
- biologically stabilized
- biologically
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CN (1) | CN1953664A (ru) |
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EA (1) | EA013401B1 (ru) |
IL (1) | IL179189A0 (ru) |
WO (1) | WO2005120173A2 (ru) |
ZA (1) | ZA200608552B (ru) |
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IN266973B (ru) | 2004-07-30 | 2007-07-06 | Kimberly Clark Co | |
US20060115536A1 (en) * | 2004-11-12 | 2006-06-01 | Board Of Regents, The University Of Texas System | Glycerin based synthesis of silver nanoparticles and nanowires |
US8333994B2 (en) * | 2007-09-17 | 2012-12-18 | The Curators Of The University Of Missouri | Stabilized, biocompatible gold nanoparticles and enviro-friendly method for making same |
US20070224288A1 (en) * | 2006-03-22 | 2007-09-27 | Kiss Nail Products, Inc. | Antibacterial gel coating and pedicure spa with antibacterial function |
WO2008104076A1 (en) * | 2007-03-01 | 2008-09-04 | Aroll Exama | Electrocolloidal silver and echinacea root antimicrobial formulation |
EA017337B1 (ru) * | 2007-07-19 | 2012-11-30 | Дели Инститьют Оф Фармасьютикал Сайнс Энд Рисерч (Дипсар) | СИНЕРГЕТИЧЕСКАЯ РАСТИТЕЛЬНАЯ КОМПОЗИЦИЯ ПРОТИВ КАТАРАКТЫ, ВКЛЮЧАЮЩАЯ СМЕСЬ ЭКСТРАКТОВ ЛЕКАРСТВЕННЫХ РАСТЕНИЙ Foeniculum vulgare, Murraya koenigii и Triphala |
ES2319064B1 (es) * | 2007-10-05 | 2010-02-15 | Universidad De Santiago De Compostela | Uso de clusteres cuanticos atomicos (aqcs) como antimicrobianos y biocidas. |
US20090232904A1 (en) * | 2008-03-13 | 2009-09-17 | Stephen Quinto | Homeopathic Skin Care Compositions and Uses Thereof |
CN101745352B (zh) * | 2009-12-15 | 2012-05-30 | 中国科学院化学研究所 | 超疏水表面材料及其专用具有核壳结构的纳米颗粒 |
MD4075C1 (ru) * | 2009-12-31 | 2011-07-31 | Анатолий ЭФКАРПИДИС | Способ получения высокодисперсного коллоидного серебра |
KR20120084681A (ko) * | 2011-01-20 | 2012-07-30 | 한양대학교 산학협력단 | 유세포 분석을 이용한 나노 물질 위해성 평가 방법 |
AU2011247875B1 (en) * | 2011-09-16 | 2012-08-09 | Robert White | Disinfectant Compositions and Uses Thereof |
CN103156802B (zh) * | 2011-10-11 | 2014-09-24 | 沈志荣 | 一种含番石榴、美洲接骨木提取物和珍珠粉的免洗睡眠面膜组合物 |
AU2013364412B2 (en) | 2012-12-21 | 2018-10-04 | Delaval Holding Ab | Germicidal compositions comprising carboxylic acid mixture and use as topical disinfectants |
EP2898878A1 (de) * | 2014-01-23 | 2015-07-29 | LTS LOHMANN Therapie-Systeme AG | Klebeband enthaltend Beinwell |
EP2905259B1 (en) * | 2014-02-05 | 2016-08-31 | King Saud University | Porous noble metal oxide nanoparticles, method for preparing the same and their use |
CN105177747A (zh) * | 2015-09-17 | 2015-12-23 | 宁波鑫泰生纺织科技有限公司 | 一种抗菌粘胶纤维及其制备方法 |
US9701552B1 (en) * | 2016-10-28 | 2017-07-11 | King Saud University | Synthesis of silver nanoparticles using fungi |
MD4542C1 (ru) * | 2017-02-15 | 2018-07-31 | Институт Микробиологии И Биотехнологии Академии Наук Молдовы | Способ культивирования цианобактерии Spirulina platensis |
MD4543C1 (ru) * | 2017-02-15 | 2018-07-31 | Институт Микробиологии И Биотехнологии Академии Наук Молдовы | Способ культивирования цианобактерии Spirulina platensis |
CN106987304A (zh) * | 2017-02-27 | 2017-07-28 | 张晓娟 | 一种米糠防腐败处理工艺 |
GB2561818B (en) * | 2017-03-30 | 2020-01-15 | Phyto Sophos Ltd | Plant extract compositions |
WO2018217761A1 (en) * | 2017-05-23 | 2018-11-29 | Hitchcock Wiley William | Antimicrobial composition |
CN107308063B (zh) * | 2017-08-08 | 2019-12-13 | 广州蜜妆生物科技有限公司 | 一种抗皱眼睛露及其制备方法 |
RU2708051C1 (ru) * | 2019-01-10 | 2019-12-03 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Ивановский государственный химико-технологический университет" (ИГХТУ) | Способ получения наночастиц серебра |
ES2778948B2 (es) * | 2019-02-12 | 2021-08-13 | Univ Valladolid | Metodo industrial de sintesis de nanoparticulas metalicas de tamano graduable |
CN111657306A (zh) * | 2020-06-19 | 2020-09-15 | 广东一芙化妆品有限公司 | 一种草本植物银离子组合物及其应用 |
KR20220057248A (ko) * | 2020-10-29 | 2022-05-09 | 주식회사 영동테크 | 민들레 추출물을 포함하는 금속 나노분말 및 이의 제조방법 |
FR3124378A1 (fr) * | 2021-06-24 | 2022-12-30 | Bobs Silver | Composition antiseptique pour administration nasale |
FR3115683A1 (fr) * | 2020-11-04 | 2022-05-06 | Bobs Silver | Composition antiseptique pour administration nasale |
WO2022096605A1 (fr) * | 2020-11-04 | 2022-05-12 | Bobs Silver | Composition antiseptique |
CO2021001399A1 (es) * | 2021-02-08 | 2022-08-09 | Zumo Tecnologia Zumotec S A | Formulación antimicrobiana que comprende nanopartículas metálicas o de óxidos metálicos sintetizados a partir de extractos vegetales |
CN113318125B (zh) * | 2021-06-04 | 2022-10-11 | 青岛农业大学 | 一种紫锥菊多糖纳米颗粒的制备方法 |
CN113427015B (zh) * | 2021-06-18 | 2022-11-01 | 上海交通大学 | 一种新型银纳米材料AgNFs的制备方法及其应用 |
CN113875464A (zh) * | 2021-09-27 | 2022-01-04 | 广西绿循环新材料技术有限责任公司 | 一种利用纳米抗菌剂联合生物防治八角炭疽病的方法 |
US11564967B1 (en) * | 2022-01-24 | 2023-01-31 | Tran Ky Huynh | Oral compositions containing extracts of a betel leaf and related methods |
US11878043B1 (en) | 2023-06-12 | 2024-01-23 | King Faisal University | Method for synthesizing silver nanoparticles from Amaranthus hybridus |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2519126A1 (de) * | 1974-05-07 | 1975-11-20 | Dick | Insektizide vorrichtung und verfahren zu deren herstellung |
US4536388A (en) * | 1983-07-18 | 1985-08-20 | Zoecon Corporation | Pest control device comprising α-cyano-3-phenoxybenzyl 2-(2-chloro-4-trifluoromethylanilino)-3-methylbutanoate |
US5411737A (en) * | 1991-10-15 | 1995-05-02 | Merck & Co., Inc. | Slow release syneresing polymeric drug delivery device |
FR2746585B1 (fr) * | 1996-03-29 | 1998-07-03 | Rhone Merieux | Collier anti-puces et anti-tiques pour chien et chat, a base de n-phenylpyrazole |
EP1066825A1 (en) * | 1999-06-17 | 2001-01-10 | The Procter & Gamble Company | An anti-microbial body care product |
WO2001003711A1 (de) * | 1999-07-08 | 2001-01-18 | Phyotopharmaka Gmbh | Verfahren zur isolierung von lipophilen wirkstoffen aus pflanzlichem und/oder tierischem material |
US6414036B1 (en) * | 1999-09-01 | 2002-07-02 | Van Beek Global/Ninkov Llc | Composition for treatment of infections of humans and animals |
DE10063864A1 (de) * | 2000-12-21 | 2002-06-27 | Bayer Ag | Pyrazoloximhaltige Formkörper zur dermalen Bekämpfung von Parasiten an Tieren |
US6962773B2 (en) * | 2001-11-30 | 2005-11-08 | Agfa Gevaert | Thermographic recording material with improved developability |
CN1369206A (zh) * | 2001-12-26 | 2002-09-18 | 骏安科技投资有限公司 | 钠米银消毒凝胶及其制备方法和应用 |
CN1243471C (zh) * | 2002-08-06 | 2006-03-01 | 中国地质大学(武汉) | 以藻类为载体的纳米银抗菌粉体及其制备方法 |
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EP1753293A4 (en) | 2008-09-17 |
WO2005120173A2 (en) | 2005-12-22 |
AU2005251570B2 (en) | 2011-03-31 |
CN1953664A (zh) | 2007-04-25 |
EP1753293A2 (en) | 2007-02-21 |
EA013401B1 (ru) | 2010-04-30 |
IL179189A0 (en) | 2007-05-15 |
AU2005251570A1 (en) | 2005-12-22 |
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