ZA200606177B - 3-'4-heterocyclyl-1,2,3,-triazol-1-yl'-n-aryl-benzamides as inhibitors of the cytokines production for the treatment of chronic inflammatory diseases - Google Patents

3-'4-heterocyclyl-1,2,3,-triazol-1-yl'-n-aryl-benzamides as inhibitors of the cytokines production for the treatment of chronic inflammatory diseases

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Publication number
ZA200606177B
ZA200606177B ZA200606177A ZA200606177A ZA200606177B ZA 200606177 B ZA200606177 B ZA 200606177B ZA 200606177 A ZA200606177 A ZA 200606177A ZA 200606177 A ZA200606177 A ZA 200606177A ZA 200606177 B ZA200606177 B ZA 200606177B
Authority
ZA
South Africa
Prior art keywords
benzamides
triazol
heterocyclyl
inhibitors
aryl
Prior art date
Application number
ZA200606177A
Other languages
English (en)
Inventor
Cogan Derek
Hao Ming-Hong
Kamhi Victor Marc
Miller Craig Andrew
Netherton Russell
Swinamer Alan David
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of ZA200606177B publication Critical patent/ZA200606177B/xx

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
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    • A61P19/00—Drugs for skeletal disorders
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • C07—ORGANIC CHEMISTRY
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    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • C07—ORGANIC CHEMISTRY
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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ZA200606177A 2004-03-09 2006-07-26 3-'4-heterocyclyl-1,2,3,-triazol-1-yl'-n-aryl-benzamides as inhibitors of the cytokines production for the treatment of chronic inflammatory diseases ZA200606177B (en)

Applications Claiming Priority (1)

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US55144504P 2004-03-09 2004-03-09

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ZA200606177B true ZA200606177B (en) 2008-12-31

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US (2) US7214802B2 (de)
EP (2) EP1725544B1 (de)
JP (1) JP4850824B2 (de)
KR (1) KR20060129077A (de)
CN (1) CN1930144A (de)
AR (1) AR048315A1 (de)
AT (1) ATE432273T1 (de)
AU (1) AU2005223738B2 (de)
BR (1) BRPI0508561A (de)
CA (1) CA2557856C (de)
CY (1) CY1109333T1 (de)
DE (1) DE602005014621D1 (de)
DK (1) DK1725544T3 (de)
EA (1) EA011634B1 (de)
EC (1) ECSP066833A (de)
ES (1) ES2327940T3 (de)
HR (1) HRP20090334T1 (de)
IL (1) IL177937A0 (de)
MY (1) MY143000A (de)
NO (1) NO20064120L (de)
NZ (1) NZ550148A (de)
PE (1) PE20051146A1 (de)
PL (1) PL1725544T3 (de)
PT (1) PT1725544E (de)
RS (1) RS50796B (de)
SI (1) SI1725544T1 (de)
TW (1) TW200602313A (de)
UA (1) UA85702C2 (de)
WO (1) WO2005090333A1 (de)
ZA (1) ZA200606177B (de)

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