ZA200603160B - Use of agomelatine in obtaining medicaments intended for the treatment of bipolar disorders - Google Patents
Use of agomelatine in obtaining medicaments intended for the treatment of bipolar disorders Download PDFInfo
- Publication number
- ZA200603160B ZA200603160B ZA200603160A ZA200603160A ZA200603160B ZA 200603160 B ZA200603160 B ZA 200603160B ZA 200603160 A ZA200603160 A ZA 200603160A ZA 200603160 A ZA200603160 A ZA 200603160A ZA 200603160 B ZA200603160 B ZA 200603160B
- Authority
- ZA
- South Africa
- Prior art keywords
- extract
- radix
- radix notoginseng
- composition
- ginsenoside
- Prior art date
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- 208000020925 Bipolar disease Diseases 0.000 title 1
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- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 description 1
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- 229910052751 metal Inorganic materials 0.000 description 1
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- 230000000926 neurological effect Effects 0.000 description 1
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- JPXMTWWFLBLUCD-UHFFFAOYSA-N nitro blue tetrazolium(2+) Chemical compound COC1=CC(C=2C=C(OC)C(=CC=2)[N+]=2N(N=C(N=2)C=2C=CC=CC=2)C=2C=CC(=CC=2)[N+]([O-])=O)=CC=C1[N+]1=NC(C=2C=CC=CC=2)=NN1C1=CC=C([N+]([O-])=O)C=C1 JPXMTWWFLBLUCD-UHFFFAOYSA-N 0.000 description 1
- FNIRVWPHRMMRQI-UHFFFAOYSA-N notoginsenoside-R2 Natural products CC(C)=CCCC(C)(O)C1CCC(C2(C3)C)(C)C1C(O)CC2C1(C)CCC(O)C(C)(C)C1C3OC1OC(CO)C(O)C(O)C1OC1OCC(O)C(O)C1O FNIRVWPHRMMRQI-UHFFFAOYSA-N 0.000 description 1
- YPUHYSBFIMWSEC-UHFFFAOYSA-N notoginsenoside-R3 Natural products C1CC(C2(CC(C3C(C)(C)C(O)CCC3(C)C2CC2O)OC3C(C(O)C(O)C(CO)O3)O)C)(C)C2C1C(C)(CCC=C(C)C)OC(C(C(O)C1O)O)OC1COC1OC(CO)C(O)C(O)C1O YPUHYSBFIMWSEC-UHFFFAOYSA-N 0.000 description 1
- 210000000956 olfactory bulb Anatomy 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- RDIMTXDFGHNINN-IKGGRYGDSA-N panaxytriol Chemical compound CCCCCCC[C@H](O)[C@@H](O)CC#CC#C[C@H](O)C=C RDIMTXDFGHNINN-IKGGRYGDSA-N 0.000 description 1
- ZCKMUKZQXWHXOF-UHFFFAOYSA-N panaxytriol Natural products CCC(C)C(C)C(C)C(C)C(C)C(O)C(O)CC#CC#CC(O)C=C ZCKMUKZQXWHXOF-UHFFFAOYSA-N 0.000 description 1
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- 230000010412 perfusion Effects 0.000 description 1
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- 229920006255 plastic film Polymers 0.000 description 1
- 229920006122 polyamide resin Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000007086 side reaction Methods 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 description 1
- PTDAHAWQAGSZDD-IOVCITQVSA-N soyasaponin I Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@H]1[C@H](O[C@H]2[C@@H](O[C@@H]([C@@H](O)[C@@H]2O)C(O)=O)O[C@@H]2[C@]([C@H]3[C@]([C@@H]4[C@@]([C@@]5(CC[C@@]6(C)[C@H](O)CC(C)(C)C[C@H]6C5=CC4)C)(C)CC3)(C)CC2)(C)CO)O[C@H](CO)[C@H](O)[C@@H]1O PTDAHAWQAGSZDD-IOVCITQVSA-N 0.000 description 1
- 238000012453 sprague-dawley rat model Methods 0.000 description 1
- 239000012086 standard solution Substances 0.000 description 1
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- 238000005303 weighing Methods 0.000 description 1
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- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0503937A FR2884714B1 (fr) | 2005-04-20 | 2005-04-20 | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement des troubles bipolaires |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200603160B true ZA200603160B (en) | 2007-06-27 |
Family
ID=35311309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200603160A ZA200603160B (en) | 2005-04-20 | 2006-04-20 | Use of agomelatine in obtaining medicaments intended for the treatment of bipolar disorders |
Country Status (41)
Country | Link |
---|---|
US (1) | US7947743B2 (el) |
EP (1) | EP1714647B1 (el) |
JP (2) | JP4580364B2 (el) |
KR (2) | KR100835451B1 (el) |
CN (2) | CN1853619B (el) |
AP (1) | AP2656A (el) |
AR (1) | AR057277A1 (el) |
AT (1) | ATE491443T1 (el) |
AU (1) | AU2006201655B2 (el) |
BR (1) | BRPI0601285A8 (el) |
CA (1) | CA2544136C (el) |
CR (1) | CR9426A (el) |
CY (1) | CY1111257T1 (el) |
DE (1) | DE602006018822D1 (el) |
DK (1) | DK1714647T3 (el) |
EA (1) | EA013462B1 (el) |
ES (1) | ES2357901T3 (el) |
FR (1) | FR2884714B1 (el) |
GE (1) | GEP20094651B (el) |
GT (1) | GT200600141A (el) |
HK (1) | HK1093906A1 (el) |
HR (1) | HRP20110083T1 (el) |
IL (1) | IL186373A (el) |
JO (1) | JO2666B1 (el) |
MA (1) | MA28266A1 (el) |
ME (1) | ME01951B (el) |
MY (1) | MY143171A (el) |
NO (1) | NO336010B1 (el) |
NZ (1) | NZ546630A (el) |
PE (1) | PE20061337A1 (el) |
PL (1) | PL1714647T3 (el) |
PT (1) | PT1714647E (el) |
RS (1) | RS51659B (el) |
SG (1) | SG126868A1 (el) |
SI (1) | SI1714647T1 (el) |
TN (1) | TNSN07364A1 (el) |
TW (2) | TW200940049A (el) |
UA (1) | UA83681C2 (el) |
UY (1) | UY29470A1 (el) |
WO (1) | WO2006111653A1 (el) |
ZA (1) | ZA200603160B (el) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2890563B1 (fr) * | 2005-09-09 | 2007-10-19 | Servier Lab | Nouvelle association entre l'agomelatine et un agent thymoregulateur et les compositions pharmaceutiques qui la contiennent |
CA2685924A1 (en) * | 2007-05-01 | 2008-11-13 | Concert Pharmaceuticals Inc. | Naphthyl(ethyl)acetamides |
FR2978916B1 (fr) * | 2011-08-10 | 2013-07-26 | Servier Lab | Composition pharmaceutique solide pour administration buccale d'agomelatine |
EP2856934A1 (en) * | 2013-10-04 | 2015-04-08 | Les Laboratoires Servier | Biomarkers for the prediction of long term remission in depression |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2658818B1 (fr) * | 1990-02-27 | 1993-12-31 | Adir Cie | Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
US5585118A (en) * | 1995-06-02 | 1996-12-17 | Brigham And Women's Hospital | Choline in the treatment of bipolar disorder |
US7122576B2 (en) * | 2001-02-27 | 2006-10-17 | Plata-Salaman Carlos R | Carbamate compounds for use in preventing or treating bipolar disorder |
FR2834890B1 (fr) * | 2002-01-23 | 2004-02-27 | Servier Lab | Composition pharmaceutique orodispersible d'agomelatine |
AR047553A1 (es) * | 2003-07-04 | 2006-01-25 | Lundbeck & Co As H | La combinacion de un inhibidor de reabsorcion de serotonina y agomelatina |
CA2551637A1 (en) * | 2003-12-24 | 2005-07-14 | Sepracor Inc. | Melatonin combination therapy for improving sleep quality |
-
2005
- 2005-04-20 FR FR0503937A patent/FR2884714B1/fr not_active Expired - Fee Related
- 2005-06-01 US US11/142,612 patent/US7947743B2/en not_active Expired - Fee Related
-
2006
- 2006-04-04 JO JO200690A patent/JO2666B1/en active
- 2006-04-04 PE PE2006000362A patent/PE20061337A1/es not_active Application Discontinuation
- 2006-04-07 GT GT200600141A patent/GT200600141A/es unknown
- 2006-04-07 UY UY29470A patent/UY29470A1/es not_active Application Discontinuation
- 2006-04-11 SG SG200602393A patent/SG126868A1/en unknown
- 2006-04-11 UA UAA200604022A patent/UA83681C2/uk unknown
- 2006-04-17 MA MA28940A patent/MA28266A1/fr unknown
- 2006-04-18 NO NO20061705A patent/NO336010B1/no not_active IP Right Cessation
- 2006-04-19 TW TW098118938A patent/TW200940049A/zh unknown
- 2006-04-19 WO PCT/FR2006/000859 patent/WO2006111653A1/fr active Application Filing
- 2006-04-19 AP AP2007004212A patent/AP2656A/xx active
- 2006-04-19 NZ NZ546630A patent/NZ546630A/en not_active IP Right Cessation
- 2006-04-19 PL PL06290636T patent/PL1714647T3/pl unknown
- 2006-04-19 SI SI200630921T patent/SI1714647T1/sl unknown
- 2006-04-19 EA EA200600600A patent/EA013462B1/ru not_active IP Right Cessation
- 2006-04-19 TW TW095113952A patent/TWI318115B/zh not_active IP Right Cessation
- 2006-04-19 EP EP06290636A patent/EP1714647B1/fr active Active
- 2006-04-19 DK DK06290636.7T patent/DK1714647T3/da active
- 2006-04-19 KR KR1020060035392A patent/KR100835451B1/ko not_active IP Right Cessation
- 2006-04-19 ES ES06290636T patent/ES2357901T3/es active Active
- 2006-04-19 DE DE602006018822T patent/DE602006018822D1/de active Active
- 2006-04-19 ME MEP-2011-231A patent/ME01951B/me unknown
- 2006-04-19 AT AT06290636T patent/ATE491443T1/de active
- 2006-04-19 GE GEAP20069356A patent/GEP20094651B/en unknown
- 2006-04-19 PT PT06290636T patent/PT1714647E/pt unknown
- 2006-04-19 MY MYPI20061783A patent/MY143171A/en unknown
- 2006-04-19 AR ARP060101537A patent/AR057277A1/es not_active Application Discontinuation
- 2006-04-19 RS RS20110110A patent/RS51659B/en unknown
- 2006-04-20 ZA ZA200603160A patent/ZA200603160B/en unknown
- 2006-04-20 AU AU2006201655A patent/AU2006201655B2/en not_active Ceased
- 2006-04-20 JP JP2006116294A patent/JP4580364B2/ja not_active Expired - Fee Related
- 2006-04-20 CA CA2544136A patent/CA2544136C/fr not_active Expired - Fee Related
- 2006-04-20 CN CN2006100764985A patent/CN1853619B/zh not_active Expired - Fee Related
- 2006-04-20 BR BRPI0601285A patent/BRPI0601285A8/pt not_active IP Right Cessation
- 2006-04-20 CN CN2010105781057A patent/CN102038669A/zh active Pending
-
2007
- 2007-01-10 HK HK07100339.3A patent/HK1093906A1/xx not_active IP Right Cessation
- 2007-09-26 TN TNP2007000364A patent/TNSN07364A1/en unknown
- 2007-10-07 IL IL186373A patent/IL186373A/en not_active IP Right Cessation
- 2007-10-08 CR CR9426A patent/CR9426A/es not_active Application Discontinuation
-
2008
- 2008-02-29 KR KR1020080018845A patent/KR20080028389A/ko not_active Application Discontinuation
-
2010
- 2010-08-06 JP JP2010177003A patent/JP5341037B2/ja not_active Expired - Fee Related
-
2011
- 2011-02-02 HR HR20110083T patent/HRP20110083T1/hr unknown
- 2011-02-23 CY CY20111100222T patent/CY1111257T1/el unknown
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