ZA200602759B - Bioartificial implant and its use and method of reducing the risk for formation of connective tissue after implantation - Google Patents
Bioartificial implant and its use and method of reducing the risk for formation of connective tissue after implantation Download PDFInfo
- Publication number
- ZA200602759B ZA200602759B ZA200602759A ZA200602759A ZA200602759B ZA 200602759 B ZA200602759 B ZA 200602759B ZA 200602759 A ZA200602759 A ZA 200602759A ZA 200602759 A ZA200602759 A ZA 200602759A ZA 200602759 B ZA200602759 B ZA 200602759B
- Authority
- ZA
- South Africa
- Prior art keywords
- implant
- barrier
- coating
- cells
- semipermeable
- Prior art date
Links
- 239000007943 implant Substances 0.000 title claims abstract description 51
- 238000000034 method Methods 0.000 title claims abstract description 17
- 210000002808 connective tissue Anatomy 0.000 title abstract description 16
- 230000015572 biosynthetic process Effects 0.000 title abstract description 5
- 238000002513 implantation Methods 0.000 title description 4
- 230000004888 barrier function Effects 0.000 claims abstract description 72
- 238000000576 coating method Methods 0.000 claims abstract description 62
- 239000011248 coating agent Substances 0.000 claims abstract description 60
- 229910052751 metal Inorganic materials 0.000 claims abstract description 25
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- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 8
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- QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 claims description 2
- 229910045601 alloy Inorganic materials 0.000 claims description 2
- 239000000956 alloy Substances 0.000 claims description 2
- 229910052715 tantalum Inorganic materials 0.000 claims description 2
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 claims description 2
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- 230000012010 growth Effects 0.000 abstract description 8
- 210000000496 pancreas Anatomy 0.000 abstract description 3
- 210000004379 membrane Anatomy 0.000 description 33
- 239000012528 membrane Substances 0.000 description 33
- 210000001519 tissue Anatomy 0.000 description 28
- 238000000502 dialysis Methods 0.000 description 16
- 210000004027 cell Anatomy 0.000 description 15
- 239000008103 glucose Substances 0.000 description 14
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 13
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- 229940072056 alginate Drugs 0.000 description 7
- 235000010443 alginic acid Nutrition 0.000 description 7
- 230000032258 transport Effects 0.000 description 7
- 229920000615 alginic acid Polymers 0.000 description 6
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- IJJWOSAXNHWBPR-HUBLWGQQSA-N 5-[(3as,4s,6ar)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-n-(6-hydrazinyl-6-oxohexyl)pentanamide Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)NCCCCCC(=O)NN)SC[C@@H]21 IJJWOSAXNHWBPR-HUBLWGQQSA-N 0.000 description 1
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- 239000000730 antalgic agent Substances 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/022—Artificial gland structures using bioreactors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Transplantation (AREA)
- Animal Behavior & Ethology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- External Artificial Organs (AREA)
- Slide Fasteners, Snap Fasteners, And Hook Fasteners (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0302599A SE526959C2 (sv) | 2003-10-02 | 2003-10-02 | Bioartificellt implantat innefattande en semipermeabel barriär samt förfarande för reducering av risken för bildning av bindrväv vid implantatet efter implantering genom att barriären förses med en permeabel beläggning av bioaktiv metall |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200602759B true ZA200602759B (en) | 2007-06-27 |
Family
ID=29247003
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200602759A ZA200602759B (en) | 2003-10-02 | 2004-10-04 | Bioartificial implant and its use and method of reducing the risk for formation of connective tissue after implantation |
Country Status (26)
Country | Link |
---|---|
US (1) | US7955613B2 (no) |
EP (1) | EP1667746B1 (no) |
JP (1) | JP4837563B2 (no) |
KR (1) | KR101181535B1 (no) |
CN (1) | CN100536937C (no) |
AT (1) | ATE405301T1 (no) |
AU (1) | AU2004275685B2 (no) |
BR (1) | BRPI0415004A (no) |
CA (1) | CA2539150C (no) |
DE (1) | DE602004016008D1 (no) |
DK (1) | DK1667746T3 (no) |
ES (1) | ES2313072T3 (no) |
HK (1) | HK1095542A1 (no) |
IL (1) | IL174488A0 (no) |
MX (1) | MXPA06003665A (no) |
NO (1) | NO328180B1 (no) |
NZ (1) | NZ546775A (no) |
PL (1) | PL1667746T3 (no) |
PT (1) | PT1667746E (no) |
RS (1) | RS20060235A (no) |
RU (1) | RU2349349C2 (no) |
SE (1) | SE526959C2 (no) |
SI (1) | SI1667746T1 (no) |
UA (1) | UA81982C2 (no) |
WO (1) | WO2005030283A1 (no) |
ZA (1) | ZA200602759B (no) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE515227C2 (sv) | 1999-04-28 | 2001-07-02 | Bruce Medical Ab | Kropp för åstadkommande av in- och tillväxt av benvävnad och/ eller bindväv och sätt för framställning av kroppen |
JP4543152B2 (ja) * | 2004-08-20 | 2010-09-15 | 独立行政法人産業技術総合研究所 | 透明チタン被覆生体適合化材料 |
WO2008103101A1 (en) * | 2007-02-19 | 2008-08-28 | Ticapex Ab | Implant assembly |
CA2680321C (en) * | 2007-03-09 | 2016-05-03 | The University Of Akron | Bio-artificial pancreas and a procedure for preparation of same |
NZ583430A (en) | 2007-08-23 | 2012-06-29 | Intrexon Corp | Methods and compositions for diagnosing disease via detecting reporter gene expression |
CA2715080C (en) | 2007-09-28 | 2021-09-28 | Intrexon Corporation | Therapeutic gene-switch constructs and bioreactors for the expression of biotherapeutic molecules, and uses thereof |
RU2525737C1 (ru) * | 2013-05-22 | 2014-08-20 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Саратовский государственный технический университет имени Гагарина Ю.А." (СГТУ имени Гагарина Ю.А.) | Способ изготовления внутрикостного стоматологического имплантата |
RU2526252C1 (ru) * | 2013-05-30 | 2014-08-20 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Саратовский государственный технический университет имени Гагарина Ю.А." (СГТУ имени Гагарина Ю.А.) | Способ изготовления внутрикостных имплантатов с многослойным покрытием |
JP7088564B2 (ja) * | 2016-11-10 | 2022-06-21 | ヴィアサイト,インコーポレイテッド | 細胞送達装置におけるpdx1膵臓内胚葉細胞及びその方法 |
JP7084566B2 (ja) * | 2017-05-29 | 2022-06-15 | 創生ライフサイエンス株式会社 | 生体適合性高分子材料のマーキング方法 |
CA3155905A1 (en) | 2019-09-27 | 2021-04-01 | Isla Technologies, Inc. | BIOARTIFICIAL PANCREAS |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4752292A (en) * | 1983-01-24 | 1988-06-21 | Icu Medical, Inc. | Medical connector |
SE450623B (sv) * | 1984-11-07 | 1987-07-13 | Dan Lundgren | Element for kontrollerad vevnadsinvext i kirurgiskt intervenerade omraden |
US5632779A (en) * | 1989-07-25 | 1997-05-27 | Smith & Nephew, Inc. | Zirconium oxide and zirconium nitride coated vascular grafts |
KR0169495B1 (ko) * | 1990-10-31 | 1999-01-15 | 쥐. 마샬 애비 | 폐쇄 혈관신생 이식 물질 |
EP0585368B1 (en) * | 1991-04-25 | 1997-08-06 | Brown University Research Foundation | Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products |
US5429821A (en) | 1992-05-29 | 1995-07-04 | The Regents Of The University Of California | Non-fibrogenic high mannuronate alginate coated transplants, processes for their manufacture, and methods for their use |
US5387327A (en) * | 1992-10-19 | 1995-02-07 | Duquesne University Of The Holy Ghost | Implantable non-enzymatic electrochemical glucose sensor |
RU2040277C1 (ru) | 1992-12-27 | 1995-07-25 | Товарищество с ограниченной ответственностью "МиТ" (Медицина и Технология) | Способ изготовления материала для имплантата с электретными свойствами для остеосинтеза |
US5876742A (en) * | 1994-01-24 | 1999-03-02 | The Regents Of The University Of California | Biological tissue transplant coated with stabilized multilayer alginate coating suitable for transplantation and method of preparation thereof |
AUPM425294A0 (en) * | 1994-03-04 | 1994-03-31 | Australian National University, The | In-vitro angiogenesis assay |
DE69630266T2 (de) * | 1995-06-07 | 2004-09-09 | W.L. Gore & Associates, Inc., Newark | Implantierbare aufnahmevorrichtung für ein therapeutisches gerät |
US5855613A (en) * | 1995-10-13 | 1999-01-05 | Islet Sheet Medical, Inc. | Retrievable bioartificial implants having dimensions allowing rapid diffusion of oxygen and rapid biological response to physiological change |
RU2113830C1 (ru) | 1996-04-02 | 1998-06-27 | Самарский государственный аэрокосмический университет им.С.П.Королева | Зубной имплантат |
RU2109495C1 (ru) | 1996-07-19 | 1998-04-27 | Наум Абрамович Иофис | Искусственный клапан сердца и способ его изготовления |
RU2117456C1 (ru) | 1996-11-18 | 1998-08-20 | Жусев Андрей Иванович | Пластиночный эндооссальный имплантант |
RU2142867C1 (ru) | 1998-02-23 | 1999-12-20 | Суслов Анатолий Григорьевич | Комбинированный (режуще-деформирующий) метчик |
RU2157245C1 (ru) | 1999-03-05 | 2000-10-10 | Антонив Василий Федорович | Способ изготовления имплантатов |
AU3724900A (en) * | 1999-03-05 | 2000-09-21 | Louis R. Matson | Surface-modified bioactive surgical implants suppressing tissue growth |
RU2185127C2 (ru) | 1999-07-19 | 2002-07-20 | Нижегородская государственная медицинская академия | Винтовой зубной имплантат |
DE19950386A1 (de) * | 1999-10-19 | 2001-05-10 | Miladin Lazarov | Biokompatibler Gegenstand |
US20020000404A1 (en) * | 2000-03-17 | 2002-01-03 | Michael Mutsakis | Filtration element for severe service applications |
JP2003530926A (ja) * | 2000-04-14 | 2003-10-21 | ヴァージニア テック インテレクチュアル プロパティーズ インコーポレイテッド | 物質の生体適合性を増強するための自己集合した薄膜コーティング |
RU2191607C2 (ru) | 2000-06-23 | 2002-10-27 | Гюнтер Виктор Эдуардович | Носитель клеточных культур искусственных внутренних органов |
AU2001273234A1 (en) | 2000-07-05 | 2002-01-14 | Islet Technology, Inc. | Method and system for consistent and effective encapsulation of biological material |
DK1381402T3 (da) | 2001-04-27 | 2010-03-08 | Vivoxid Oy | Fremgangsmåde til forbedring af blødvævsmodtagelse og implantater der gør brug af denne fremgangsmåde |
US7163688B2 (en) * | 2001-06-22 | 2007-01-16 | Alza Corporation | Osmotic implant with membrane and membrane retention means |
SE0200269D0 (sv) | 2002-01-31 | 2002-01-31 | Ellem Bioteknik Ab | Material for implantation |
US7458991B2 (en) * | 2002-02-08 | 2008-12-02 | Howmedica Osteonics Corp. | Porous metallic scaffold for tissue ingrowth |
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2003
- 2003-10-02 SE SE0302599A patent/SE526959C2/sv not_active IP Right Cessation
-
2004
- 2004-04-10 UA UAA200604785A patent/UA81982C2/uk unknown
- 2004-10-04 WO PCT/SE2004/001418 patent/WO2005030283A1/en active Application Filing
- 2004-10-04 AU AU2004275685A patent/AU2004275685B2/en not_active Ceased
- 2004-10-04 CA CA2539150A patent/CA2539150C/en not_active Expired - Fee Related
- 2004-10-04 KR KR1020067008504A patent/KR101181535B1/ko not_active IP Right Cessation
- 2004-10-04 JP JP2006532233A patent/JP4837563B2/ja not_active Expired - Fee Related
- 2004-10-04 US US10/574,114 patent/US7955613B2/en not_active Expired - Fee Related
- 2004-10-04 NZ NZ546775A patent/NZ546775A/en not_active IP Right Cessation
- 2004-10-04 RU RU2006114350/15A patent/RU2349349C2/ru not_active IP Right Cessation
- 2004-10-04 AT AT04775510T patent/ATE405301T1/de active
- 2004-10-04 ES ES04775510T patent/ES2313072T3/es active Active
- 2004-10-04 EP EP04775510A patent/EP1667746B1/en active Active
- 2004-10-04 MX MXPA06003665A patent/MXPA06003665A/es active IP Right Grant
- 2004-10-04 DE DE602004016008T patent/DE602004016008D1/de active Active
- 2004-10-04 PL PL04775510T patent/PL1667746T3/pl unknown
- 2004-10-04 ZA ZA200602759A patent/ZA200602759B/en unknown
- 2004-10-04 SI SI200430926T patent/SI1667746T1/sl unknown
- 2004-10-04 BR BRPI0415004-0A patent/BRPI0415004A/pt not_active IP Right Cessation
- 2004-10-04 CN CNB200480028566XA patent/CN100536937C/zh not_active Expired - Fee Related
- 2004-10-04 DK DK04775510T patent/DK1667746T3/da active
- 2004-10-04 RS YUP-2006/0235A patent/RS20060235A/sr unknown
- 2004-10-04 PT PT04775510T patent/PT1667746E/pt unknown
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2006
- 2006-03-22 IL IL174488A patent/IL174488A0/en not_active IP Right Cessation
- 2006-04-28 NO NO20061899A patent/NO328180B1/no not_active IP Right Cessation
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- 2007-01-17 HK HK07100590.7A patent/HK1095542A1/xx not_active IP Right Cessation
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