ZA200508930B - Vectors and cells for preparing immunoprotective compositions derived from transgenic plants - Google Patents

Vectors and cells for preparing immunoprotective compositions derived from transgenic plants Download PDF

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Publication number
ZA200508930B
ZA200508930B ZA200508930A ZA200508930A ZA200508930B ZA 200508930 B ZA200508930 B ZA 200508930B ZA 200508930 A ZA200508930 A ZA 200508930A ZA 200508930 A ZA200508930 A ZA 200508930A ZA 200508930 B ZA200508930 B ZA 200508930B
Authority
ZA
South Africa
Prior art keywords
plant
antigen
fruit
vaccine
protein
Prior art date
Application number
ZA200508930A
Other languages
English (en)
Inventor
Guy A Cardineau
Mason Hugh Stanley
Joyce M Vaneck
Dwayne D Kirk
Walmsley Amanda Maree
Original Assignee
Thompson Boyce Inst Plant Research
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thompson Boyce Inst Plant Research, Dow Agrosciences Llc filed Critical Thompson Boyce Inst Plant Research
Publication of ZA200508930B publication Critical patent/ZA200508930B/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • C12N15/68Stabilisation of the vector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA200508930A 2003-05-05 2004-05-04 Vectors and cells for preparing immunoprotective compositions derived from transgenic plants ZA200508930B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46799803P 2003-05-05 2003-05-05

Publications (1)

Publication Number Publication Date
ZA200508930B true ZA200508930B (en) 2007-03-28

Family

ID=33435152

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200508930A ZA200508930B (en) 2003-05-05 2004-05-04 Vectors and cells for preparing immunoprotective compositions derived from transgenic plants

Country Status (13)

Country Link
US (3) US7132291B2 (fr)
EP (1) EP1620550B1 (fr)
KR (1) KR20060035596A (fr)
CN (1) CN100393870C (fr)
AR (1) AR044246A1 (fr)
AT (1) ATE473271T1 (fr)
AU (1) AU2004235813B2 (fr)
BR (1) BRPI0410340A (fr)
CA (1) CA2524293A1 (fr)
DE (1) DE602004028004D1 (fr)
NZ (1) NZ543348A (fr)
WO (1) WO2004098533A2 (fr)
ZA (1) ZA200508930B (fr)

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BRPI0707733B1 (pt) * 2006-02-13 2019-12-31 Fraunhofer Usa Inc antígeno isolado, composição de vacina, uso da referida composição e método para produção de uma proteína de antígeno
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BRPI0713671A2 (pt) * 2006-06-16 2013-12-03 Dow Agrosciences Llc Sequências de dna, vetores e proteínas de hemaglutinina de influenza aviária
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CA2685558A1 (fr) * 2007-04-28 2008-11-06 Fraunhofer Usa, Inc. Antigenes de trypanosome, compositions de vaccins et procedes associes
US20110008837A1 (en) * 2007-06-15 2011-01-13 Marc-Andre D-Aoust Modifying glycoprotein production in plans
KR100964462B1 (ko) * 2007-07-10 2010-06-16 성균관대학교산학협력단 형질전환 식물 유래의 조류독감 바이러스 백신 및 그 제조방법
CA2692933C (fr) 2007-07-11 2016-10-18 Fraunhofer Usa, Inc. Antigenes yersinia pestis, compositions de vaccins, et methodes associees
CA2615372A1 (fr) * 2007-07-13 2009-01-13 Marc-Andre D'aoust Particules semblables au virus grippal a comprenant de l'hemagglutinine
CA2696764A1 (fr) * 2007-08-20 2009-02-26 Fraunhofer Usa, Inc. Vaccins antigrippaux prophylactiques et therapeutiques, antigenes, compositions et procedes
MX2010007962A (es) * 2007-11-27 2010-11-10 Medicago Inc Particulas tipo virus de influenza recombinante (vlp) producidas en plantas transgenicas que expresan hemaglutinina.
KR101956910B1 (ko) * 2008-01-21 2019-03-12 메디카고 인코포레이티드 헤마글루티닌을 발현하는 트랜스제닉 식물에서 생산된 재조합 인플루엔자 바이러스-유사 입자(VLPs)
US8771703B2 (en) 2008-07-08 2014-07-08 Medicago Inc. Soluble recombinant influenza antigens
MX370690B (es) 2008-07-18 2019-12-19 Medicago Inc Epitopo de inmunizacion de nuevo virus de la influenza.
US8734803B2 (en) 2008-09-28 2014-05-27 Ibio Inc. Humanized neuraminidase antibody and methods of use thereof
US9233148B2 (en) * 2009-01-09 2016-01-12 Samuel Bogoch Replikin-based compounds for prevention and treatment of influenza and methods of differentiating infectivity and lethality in influenza
WO2010117786A1 (fr) 2009-03-30 2010-10-14 Mount Sinai School Of Medicine Of New York University Vaccins pour le virus influenza et leurs utilisations
US10272148B2 (en) 2009-06-24 2019-04-30 Medicago Inc. Chimeric influenza virus-like particles comprising hemagglutinin
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AU2010339544B2 (en) 2009-12-28 2015-11-12 Merial Limited Production of hemagglutinin-neuraminidase protein in microalgae
KR20120132506A (ko) 2010-02-18 2012-12-05 마운트 시나이 스쿨 오브 메디슨 인플루엔자 바이러스 질환의 예방 및 치료에 사용되는 백신
KR20130075732A (ko) 2010-03-30 2013-07-05 마운트 시나이 스쿨 오브 메디슨 인플루엔자 바이러스 백신 및 이의 용도
CA2816190C (fr) 2010-10-27 2020-03-24 Philip Morris Products S.A. Procedes de capture de particules de type viral a partir de plantes a l'aide d'une chromatographie en lit expanse
TWI620816B (zh) 2011-03-23 2018-04-11 苜蓿股份有限公司 植物衍生蛋白回收方法
AU2012312529B2 (en) 2011-09-20 2018-01-04 Icahn School Of Medicine At Mount Sinai Influenza virus vaccines and uses thereof
US11390878B2 (en) 2011-09-30 2022-07-19 Medicago Inc. Increasing protein yield in plants
CA2850407C (fr) * 2011-09-30 2021-11-23 Medicago Inc. Augmentation du rendement en particules de type viral dans des plantes
WO2014099931A1 (fr) 2012-12-18 2014-06-26 Icahn School Of Medicine At Mount Sinai Vaccins contre le virus de la grippe et leurs utilisations
WO2014159960A1 (fr) 2013-03-14 2014-10-02 Icahn School Of Medicine At Mount Sinai Anticorps contre l'hémagglutinine du virus de la grippe et utilisations correspondantes
EP2978848B1 (fr) 2013-03-28 2020-05-06 Medicago Inc. Production de particules de type viral de la grippe dans des plantes
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Also Published As

Publication number Publication date
AU2004235813A1 (en) 2004-11-18
WO2004098533A3 (fr) 2005-08-04
EP1620550B1 (fr) 2010-07-07
US20050048074A1 (en) 2005-03-03
US20090017065A1 (en) 2009-01-15
BRPI0410340A (pt) 2006-05-30
KR20060035596A (ko) 2006-04-26
CN100393870C (zh) 2008-06-11
CN1788077A (zh) 2006-06-14
US20080076177A1 (en) 2008-03-27
ATE473271T1 (de) 2010-07-15
US7407802B2 (en) 2008-08-05
CA2524293A1 (fr) 2004-11-18
NZ543348A (en) 2008-08-29
EP1620550A4 (fr) 2006-06-14
EP1620550A2 (fr) 2006-02-01
US7132291B2 (en) 2006-11-07
AR044246A1 (es) 2005-09-07
AU2004235813B2 (en) 2010-07-29
DE602004028004D1 (de) 2010-08-19
WO2004098533A2 (fr) 2004-11-18

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