ZA200508315B - Compositions containing piperacillin and tazobactam useful for injection - Google Patents
Compositions containing piperacillin and tazobactam useful for injection Download PDFInfo
- Publication number
- ZA200508315B ZA200508315B ZA200508315A ZA200508315A ZA200508315B ZA 200508315 B ZA200508315 B ZA 200508315B ZA 200508315 A ZA200508315 A ZA 200508315A ZA 200508315 A ZA200508315 A ZA 200508315A ZA 200508315 B ZA200508315 B ZA 200508315B
- Authority
- ZA
- South Africa
- Prior art keywords
- pharmaceutical composition
- composition according
- piperacillin
- tazobactam
- pharmaceutically acceptable
- Prior art date
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- 229960002292 piperacillin Drugs 0.000 title claims description 49
- LPQZKKCYTLCDGQ-WEDXCCLWSA-N tazobactam Chemical compound C([C@]1(C)S([C@H]2N(C(C2)=O)[C@H]1C(O)=O)(=O)=O)N1C=CN=N1 LPQZKKCYTLCDGQ-WEDXCCLWSA-N 0.000 title claims description 33
- 229960003865 tazobactam Drugs 0.000 title claims description 31
- 239000007924 injection Substances 0.000 title claims description 7
- 238000002347 injection Methods 0.000 title claims description 7
- IVBHGBMCVLDMKU-GXNBUGAJSA-N piperacillin Chemical compound O=C1C(=O)N(CC)CCN1C(=O)N[C@H](C=1C=CC=CC=1)C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 IVBHGBMCVLDMKU-GXNBUGAJSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 claims description 85
- WCMIIGXFCMNQDS-IDYPWDAWSA-M piperacillin sodium Chemical compound [Na+].O=C1C(=O)N(CC)CCN1C(=O)N[C@H](C=1C=CC=CC=1)C(=O)N[C@@H]1C(=O)N2[C@@H](C([O-])=O)C(C)(C)S[C@@H]21 WCMIIGXFCMNQDS-IDYPWDAWSA-M 0.000 claims description 66
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
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- A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
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- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP1589901A4 (en) * | 2002-12-20 | 2006-08-09 | Generipharm Inc | INTRACUTANEOUS INJECTION |
| DE602004010862T2 (de) * | 2003-04-14 | 2009-01-02 | Wyeth Holdings Corp. | Zusammensetzungen enthaltend Piperacillin und Tazobactam zur Injektion |
| MX2007004490A (es) * | 2004-10-14 | 2007-05-08 | Wyeth Corp | Composiciones que contienen piperacilina, tazobactam y un acido aminocarboxilico en un diluyente de lactato de sodio. |
| RU2397768C2 (ru) * | 2004-12-02 | 2010-08-27 | Венус Ремедиз Лимитед | Композиции для преодоления опосредованной бета-лактамазой резистентности к антибиотикам с использованием ингибитора бета-лактамазы, предназначенные для инъекции |
| ES2284318B1 (es) * | 2005-04-13 | 2008-11-01 | Labiana Development, S.L. | Procedimiento de obtencion de una mezcla en polvo de una sal sodica de piperaciclina y tazobactama, util para su administracion por via inyectable. |
| ITMI20051630A1 (it) * | 2005-09-02 | 2007-03-03 | Acs Dobfar Spa | Formulazione farmaceutica sterile iniettabile contenente almeno due principi attivi |
| CN1927201B (zh) * | 2006-08-25 | 2011-06-01 | 天津和美生物技术有限公司 | 含哌拉西林的抗生素复方 |
| CN102441169A (zh) * | 2006-08-25 | 2012-05-09 | 天津和美生物技术有限公司 | 含β-内酰胺类抗生素和离子螯合剂的抗生素复方 |
| CN101129381B (zh) * | 2006-08-25 | 2012-02-01 | 天津和美生物技术有限公司 | 含β-内酰胺类抗生素和离子螯合剂的抗生素复方 |
| CN101129383B (zh) * | 2006-08-25 | 2014-04-02 | 天津和美生物技术有限公司 | 含氨基糖苷类抗生素的抗生素复方 |
| CN101129382B (zh) * | 2006-08-25 | 2013-12-25 | 天津和美生物技术有限公司 | 含β-内酰胺类抗生素和缓冲组分的抗生素复方 |
| CN102210679B (zh) * | 2006-08-25 | 2013-03-13 | 天津和美生物技术有限公司 | 含哌拉西林的抗生素复方 |
| CN101265263B (zh) * | 2008-05-12 | 2010-06-02 | 海南百那医药发展有限公司 | 哌拉西林钠他唑巴坦钠复方注射剂的生产方法 |
| WO2010013640A1 (ja) * | 2008-07-28 | 2010-02-04 | Yamaguchi Keizo | 感染症治療効果増強剤 |
| JP5852316B2 (ja) * | 2010-03-30 | 2016-02-03 | 富山化学工業株式会社 | ピペラシリン含有懸濁液の製造法 |
| WO2012012460A1 (en) | 2010-07-19 | 2012-01-26 | Xeris Pharmaceuticals, Inc. | Stable glucagon formulations for the treatment of hypoglycemia |
| AP2013006947A0 (en) | 2010-11-25 | 2013-06-30 | Orchid Chemicals & Pharm Ltd | Compounds and their use |
| CN105853348B (zh) | 2011-03-10 | 2019-08-30 | Xeris药物公司 | 肠胃外注射用稳定溶液 |
| KR102007057B1 (ko) | 2011-10-31 | 2019-08-02 | 엑스에리스 파머수티클스, 인크. | 당뇨병 치료를 위한 제형물 |
| UA113981C2 (xx) | 2012-03-26 | 2017-04-10 | Офтальмологічний розчин, що містить диквафасол | |
| US9125805B2 (en) | 2012-06-27 | 2015-09-08 | Xeris Pharmaceuticals, Inc. | Stable formulations for parenteral injection of small molecule drugs |
| US8476425B1 (en) | 2012-09-27 | 2013-07-02 | Cubist Pharmaceuticals, Inc. | Tazobactam arginine compositions |
| KR101816798B1 (ko) * | 2012-10-19 | 2018-01-10 | 주식회사유한양행 | 피페라실린 또는 그의 염, 타조박탐 또는 그의 염 및 덱사메타손 포스페이트 또는 그의 염을 포함하는 국소투여용 약학 조성물 |
| US9018162B2 (en) | 2013-02-06 | 2015-04-28 | Xeris Pharmaceuticals, Inc. | Methods for rapidly treating severe hypoglycemia |
| US9872906B2 (en) | 2013-03-15 | 2018-01-23 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
| AU2014227660B2 (en) | 2013-03-15 | 2014-11-06 | Merck Sharp & Dohme Llc | Ceftolozane antibiotic compositions |
| US20140274991A1 (en) | 2013-03-15 | 2014-09-18 | Cubist Pharmaceuticals, Inc. | Ceftolozane pharmaceutical compositions |
| WO2015035376A2 (en) | 2013-09-09 | 2015-03-12 | Calixa Therapeutics, Inc. | Treating infections with ceftolozane/tazobactam in subjects having impaired renal function |
| US20150094293A1 (en) | 2013-09-27 | 2015-04-02 | Calixa Therapeutics, Inc. | Solid forms of ceftolozane |
| EP3185932A1 (en) | 2014-08-06 | 2017-07-05 | Xeris Pharmaceuticals, Inc. | Syringes, kits, and methods for intracutaneous and/or subcutaneous injection of pastes |
| CN106714799A (zh) * | 2014-10-08 | 2017-05-24 | 泽井制药株式会社 | 冷冻干燥制剂的制造方法 |
| US9649364B2 (en) | 2015-09-25 | 2017-05-16 | Xeris Pharmaceuticals, Inc. | Methods for producing stable therapeutic formulations in aprotic polar solvents |
| US11590205B2 (en) | 2015-09-25 | 2023-02-28 | Xeris Pharmaceuticals, Inc. | Methods for producing stable therapeutic glucagon formulations in aprotic polar solvents |
| RU2017144216A (ru) * | 2016-03-31 | 2019-06-18 | Вокхардт Лимитед | Антибактериальные композиции |
| WO2018025248A1 (en) * | 2016-08-05 | 2018-02-08 | Jodas Expoim Private Limited | Edta injection and process for making the same |
| JP7299166B2 (ja) | 2017-06-02 | 2023-06-27 | ゼリス ファーマシューティカルズ インコーポレイテッド | 沈殿抵抗性低分子薬物製剤 |
| US11110054B2 (en) | 2018-05-09 | 2021-09-07 | Slayback Pharma Llc | Ready-to-use injectable pharmaceutical compositions comprising neostigmine and glycopyrrolate |
| CN112618486B (zh) * | 2020-12-24 | 2023-07-18 | 浙江昂利康制药股份有限公司 | 一种注射用混悬油剂及其制备方法 |
| CN113209030B (zh) * | 2021-04-27 | 2023-04-25 | 海南通用康力制药有限公司 | 哌拉西林钠他唑巴坦钠无菌粉针剂的制备方法 |
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| US4477452A (en) * | 1981-03-26 | 1984-10-16 | American Cyanamid Company | Composition of matter comprising a lyophilized preparation of a penicillin derivative |
| US4534977A (en) * | 1981-03-26 | 1985-08-13 | American Cyanamid Company | Composition of matter comprising a low bulk density lyophilized preparation of Sodium Piperacillin |
| US4562073A (en) * | 1982-12-24 | 1985-12-31 | Taiho Pharmaceutical Company Limited | Penicillin derivatives |
| US5763480A (en) * | 1994-02-14 | 1998-06-09 | The Jewish Hospital Of St. Louis | Inhibitors of cell-medicated disorders |
| US5580856A (en) | 1994-07-15 | 1996-12-03 | Prestrelski; Steven J. | Formulation of a reconstituted protein, and method and kit for the production thereof |
| US6503881B2 (en) * | 1996-08-21 | 2003-01-07 | Micrologix Biotech Inc. | Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics |
| US6207661B1 (en) * | 1999-02-22 | 2001-03-27 | Baxter International Inc. | Premixed formulation of piperacillin sodium and tazobactam sodium injection |
| WO2003088914A2 (en) * | 2002-04-18 | 2003-10-30 | The University Of Iowa Research Foundation | Methods of inhibiting and treating bacterial biofilms by metal chelators |
| US6900184B2 (en) * | 2003-04-14 | 2005-05-31 | Wyeth Holdings Corporation | Compositions containing pipercillin and tazobactam useful for injection |
| AU2003230899A1 (en) * | 2003-04-14 | 2004-11-26 | Wyeth Holdings Corporation | Compositions containing piperacillin and tazobactam useful for injection |
| DE602004010862T2 (de) * | 2003-04-14 | 2009-01-02 | Wyeth Holdings Corp. | Zusammensetzungen enthaltend Piperacillin und Tazobactam zur Injektion |
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2004
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- 2004-04-06 CN CN2004800159296A patent/CN1802179B/zh not_active Expired - Lifetime
- 2004-04-06 AT AT04076075T patent/ATE381947T1/de active
- 2004-04-06 SI SI200430609T patent/SI1468697T1/sl unknown
- 2004-04-06 RU RU2005135135/15A patent/RU2322980C2/ru active
- 2004-04-06 DK DK04076075T patent/DK1468697T3/da active
- 2004-04-07 AU AU2004229407A patent/AU2004229407B2/en not_active Expired
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- 2004-04-07 JP JP2006509780A patent/JP4644659B2/ja not_active Expired - Lifetime
- 2004-04-07 KR KR1020057019689A patent/KR100824554B1/ko active IP Right Grant
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- 2004-04-09 FR FR0403786A patent/FR2853547B1/fr not_active Expired - Fee Related
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- 2005-10-18 NO NO20054789A patent/NO20054789L/no not_active Application Discontinuation
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