ZA200505190B - Thiophene carboxamides as inhibitors of the enzyme IKK-2 - Google Patents
Thiophene carboxamides as inhibitors of the enzyme IKK-2 Download PDFInfo
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- ZA200505190B ZA200505190B ZA200505190A ZA200505190A ZA200505190B ZA 200505190 B ZA200505190 B ZA 200505190B ZA 200505190 A ZA200505190 A ZA 200505190A ZA 200505190 A ZA200505190 A ZA 200505190A ZA 200505190 B ZA200505190 B ZA 200505190B
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Classifications
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- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
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- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
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Applications Claiming Priority (1)
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SE0300091A SE0300091D0 (sv) | 2003-01-15 | 2003-01-15 | Novel compounds |
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EP (1) | EP1583756B9 (de) |
JP (1) | JP4568714B2 (de) |
KR (1) | KR20050098248A (de) |
CN (1) | CN1315820C (de) |
AT (1) | ATE374762T1 (de) |
BR (1) | BRPI0406774A (de) |
CA (1) | CA2512336A1 (de) |
CY (1) | CY1107817T1 (de) |
DE (1) | DE602004009283T2 (de) |
DK (1) | DK1583756T3 (de) |
ES (1) | ES2293206T3 (de) |
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MX (1) | MXPA05007340A (de) |
NO (1) | NO20053810L (de) |
NZ (1) | NZ541219A (de) |
PT (1) | PT1583756E (de) |
SE (1) | SE0300091D0 (de) |
WO (1) | WO2004063185A1 (de) |
ZA (1) | ZA200505190B (de) |
Families Citing this family (17)
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GB0003154D0 (en) * | 2000-02-12 | 2000-04-05 | Astrazeneca Uk Ltd | Novel compounds |
SE0102616D0 (sv) | 2001-07-25 | 2001-07-25 | Astrazeneca Ab | Novel compounds |
SE0300091D0 (sv) | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
SE0300092D0 (sv) * | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
RU2006107782A (ru) | 2003-08-15 | 2006-08-10 | Астразенека Аб (Se) | Замещенные тиофены и их применение |
BRPI0418351A (pt) * | 2004-01-05 | 2007-05-08 | Astrazeneca Ab | composto ou um sal farmaceuticamente aceitável do mesmo, métodos de limitar a proliferação celular em um humano ou animal, de tratamento de um humano ou animal sofrendo de cáncer, de tratamento de profilaxia de cáncer, de tratamento de um humano ou animal sofrendo de uma doença neoplásica, de tratamento de um humano ou animal sofrendo de uma doença prolifetativa de tratamento de cáncer, para o tratamento de infecções associadas com cáncer, para o tratamento profilático de infecções associadas com cáncer, composição farmacêutica, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, método de inibir a chk1 quinase, e, processo para a preparação de um composto ou um sal farmaceuticamente aceitável do mesmo |
WO2005105777A1 (en) * | 2004-05-05 | 2005-11-10 | Pharmacia & Upjohn Company Llc | Substituted thiophene amide compounds for the treatment of inflammation |
EP2119703B1 (de) * | 2007-01-15 | 2012-12-12 | Santen Pharmaceutical Co., Ltd | Neues indolderivat mit hemmender wirkung auf i-b-kinase |
JPWO2009096198A1 (ja) * | 2008-02-01 | 2011-05-26 | 一般社団法人ファルマIp | 新規ビアリール誘導体 |
BRPI0822522A2 (pt) * | 2008-04-23 | 2018-06-05 | Chroma Therapeutics Ltd | Inibidores da proteína quinase ikk-beta serina- treonina |
US8445529B2 (en) * | 2008-07-14 | 2013-05-21 | Santen Pharmaceutical Co., Ltd. | Indole derivative having, carbamoyl group, ureido group and substituted oxy group |
GB0907120D0 (en) * | 2009-04-24 | 2009-06-03 | Chroma Therapeutics Ltd | Inhibitors of IKK-ß serine-threonine protein kinase |
GB0913345D0 (en) | 2009-07-31 | 2009-09-16 | Astrazeneca Ab | New combination 802 |
WO2011061527A1 (en) | 2009-11-17 | 2011-05-26 | Astrazeneca Ab | Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases |
GB201016912D0 (en) | 2010-10-07 | 2010-11-24 | Astrazeneca Ab | Novel combination |
GB201021979D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | New compound |
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Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
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GB1468012A (en) * | 1973-08-09 | 1977-03-23 | Beecham Group Ltd | 2-amino-3-carboxy-thiophene derivatives |
DE3529247A1 (de) | 1985-05-17 | 1986-11-20 | Bayer Ag, 5090 Leverkusen | Verwendung von thienylharnstoffen und -isoharnstoffen als leistungsfoerdernde mittel bei tieren, neue thienylharnstoffe und -isoharnstoffe und ihre herstellung |
GB2195634B (en) | 1986-10-01 | 1990-08-15 | Roussel Lab Ltd | Thiophene derivatives |
US5258357A (en) | 1989-10-07 | 1993-11-02 | Basf Aktiengesellschaft | Carboxamides, their preparation and their use as herbicides |
US5378703A (en) | 1990-04-09 | 1995-01-03 | Alcon Laboratories, Inc. | Sulfonamides useful as carbonic anhydrase inhibitors |
US5571810A (en) | 1990-06-11 | 1996-11-05 | Fujisawa Pharmaceutical Co., Ltd. | Thiophene derivatives |
US5514801A (en) * | 1992-12-29 | 1996-05-07 | Monsanto Company | Cyclic sulfone containing retroviral protease inhibitors |
WO1998002430A1 (en) | 1996-07-11 | 1998-01-22 | Pfizer Pharmaceuticals Inc. | Pyridylpyrrole compounds useful as interleukin- and tnf antagonists |
PT853083E (pt) | 1997-01-06 | 2001-12-28 | Pfizer | Composto de piridilfurano e piridiltiofeno e sua utilizacao farmaceutica |
US6809088B2 (en) | 1997-03-24 | 2004-10-26 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them |
US6117911A (en) * | 1997-04-11 | 2000-09-12 | Neorx Corporation | Compounds and therapies for the prevention of vascular and non-vascular pathologies |
US6037340A (en) | 1997-05-28 | 2000-03-14 | Cadus Pharmaceutical Corporation | Synthesis and use of thiophene- and pyrrole-based heteroaromatic compounds |
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-
2003
- 2003-01-15 SE SE0300091A patent/SE0300091D0/xx unknown
-
2004
- 2004-01-13 PT PT04701632T patent/PT1583756E/pt unknown
- 2004-01-13 KR KR1020057013033A patent/KR20050098248A/ko not_active Application Discontinuation
- 2004-01-13 JP JP2006500206A patent/JP4568714B2/ja not_active Expired - Fee Related
- 2004-01-13 AT AT04701632T patent/ATE374762T1/de active
- 2004-01-13 BR BR0406774-6A patent/BRPI0406774A/pt not_active IP Right Cessation
- 2004-01-13 NZ NZ541219A patent/NZ541219A/en not_active IP Right Cessation
- 2004-01-13 WO PCT/GB2004/000106 patent/WO2004063185A1/en active IP Right Grant
- 2004-01-13 ES ES04701632T patent/ES2293206T3/es not_active Expired - Lifetime
- 2004-01-13 CA CA002512336A patent/CA2512336A1/en not_active Abandoned
- 2004-01-13 CN CNB2004800023046A patent/CN1315820C/zh not_active Expired - Fee Related
- 2004-01-13 MX MXPA05007340A patent/MXPA05007340A/es active IP Right Grant
- 2004-01-13 DK DK04701632T patent/DK1583756T3/da active
- 2004-01-13 EP EP04701632A patent/EP1583756B9/de not_active Expired - Lifetime
- 2004-01-13 DE DE602004009283T patent/DE602004009283T2/de not_active Expired - Lifetime
- 2004-01-13 US US10/542,044 patent/US7553868B2/en not_active Expired - Fee Related
-
2005
- 2005-06-27 ZA ZA200505190A patent/ZA200505190B/en unknown
- 2005-06-29 IL IL169478A patent/IL169478A/en not_active IP Right Cessation
- 2005-08-12 NO NO20053810A patent/NO20053810L/no not_active Application Discontinuation
-
2006
- 2006-03-08 HK HK06103016A patent/HK1082250A1/xx not_active IP Right Cessation
-
2007
- 2007-11-29 CY CY20071101528T patent/CY1107817T1/el unknown
-
2009
- 2009-05-04 US US12/435,054 patent/US20090215829A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE602004009283T2 (de) | 2008-07-10 |
JP2006515355A (ja) | 2006-05-25 |
WO2004063185A8 (en) | 2004-09-23 |
MXPA05007340A (es) | 2005-09-30 |
AU2004203967A1 (en) | 2004-07-29 |
SE0300091D0 (sv) | 2003-01-15 |
NZ541219A (en) | 2008-03-28 |
KR20050098248A (ko) | 2005-10-11 |
HK1082250A1 (en) | 2006-06-02 |
EP1583756B1 (de) | 2007-10-03 |
EP1583756A1 (de) | 2005-10-12 |
DE602004009283D1 (de) | 2007-11-15 |
US7553868B2 (en) | 2009-06-30 |
CY1107817T1 (el) | 2013-06-19 |
US20060111431A1 (en) | 2006-05-25 |
IL169478A0 (en) | 2009-02-11 |
NO20053810D0 (no) | 2005-08-12 |
BRPI0406774A (pt) | 2005-12-27 |
ES2293206T3 (es) | 2008-03-16 |
DK1583756T3 (da) | 2007-12-17 |
ATE374762T1 (de) | 2007-10-15 |
WO2004063185A1 (en) | 2004-07-29 |
CN1315820C (zh) | 2007-05-16 |
CA2512336A1 (en) | 2004-07-29 |
EP1583756B9 (de) | 2008-01-09 |
PT1583756E (pt) | 2007-12-03 |
JP4568714B2 (ja) | 2010-10-27 |
CN1738812A (zh) | 2006-02-22 |
NO20053810L (no) | 2005-10-12 |
US20090215829A1 (en) | 2009-08-27 |
IL169478A (en) | 2010-02-17 |
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