SE0300091D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0300091D0
SE0300091D0 SE0300091A SE0300091A SE0300091D0 SE 0300091 D0 SE0300091 D0 SE 0300091D0 SE 0300091 A SE0300091 A SE 0300091A SE 0300091 A SE0300091 A SE 0300091A SE 0300091 D0 SE0300091 D0 SE 0300091D0
Authority
SE
Sweden
Prior art keywords
novel compounds
therapy
processes
formula
preparation
Prior art date
Application number
SE0300091A
Other languages
English (en)
Swedish (sv)
Inventor
Andrew Morley
Philip Poyser
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0300091A priority Critical patent/SE0300091D0/xx
Publication of SE0300091D0 publication Critical patent/SE0300091D0/xx
Priority to PCT/GB2004/000106 priority patent/WO2004063185A1/en
Priority to MXPA05007340A priority patent/MXPA05007340A/es
Priority to BR0406774-6A priority patent/BRPI0406774A/pt
Priority to JP2006500206A priority patent/JP4568714B2/ja
Priority to DK04701632T priority patent/DK1583756T3/da
Priority to CNB2004800023046A priority patent/CN1315820C/zh
Priority to US10/542,044 priority patent/US7553868B2/en
Priority to PT04701632T priority patent/PT1583756E/pt
Priority to DE602004009283T priority patent/DE602004009283T2/de
Priority to KR1020057013033A priority patent/KR20050098248A/ko
Priority to AT04701632T priority patent/ATE374762T1/de
Priority to NZ541219A priority patent/NZ541219A/en
Priority to EP04701632A priority patent/EP1583756B9/en
Priority to AU2004203967A priority patent/AU2004203967B2/en
Priority to CA002512336A priority patent/CA2512336A1/en
Priority to SI200430502T priority patent/SI1583756T1/sl
Priority to ES04701632T priority patent/ES2293206T3/es
Priority to ZA200505190A priority patent/ZA200505190B/en
Priority to IL169478A priority patent/IL169478A/en
Priority to NO20053810A priority patent/NO20053810L/no
Priority to HK06103016A priority patent/HK1082250A1/xx
Priority to CY20071101528T priority patent/CY1107817T1/el
Priority to US12/435,054 priority patent/US20090215829A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
  • AIDS & HIV (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
SE0300091A 2003-01-15 2003-01-15 Novel compounds SE0300091D0 (sv)

Priority Applications (24)

Application Number Priority Date Filing Date Title
SE0300091A SE0300091D0 (sv) 2003-01-15 2003-01-15 Novel compounds
ES04701632T ES2293206T3 (es) 2003-01-15 2004-01-13 Tiofeno-carboxamidas utilizados como inhibidores de la enzima ikk-2.
KR1020057013033A KR20050098248A (ko) 2003-01-15 2004-01-13 효소 ikk-2의 저해제로서의 티오펜 카르복사미드
NZ541219A NZ541219A (en) 2003-01-15 2004-01-13 Thiophene carboxamides as inhibitors of the enzyme IKK-2
BR0406774-6A BRPI0406774A (pt) 2003-01-15 2004-01-13 Derivados de tiofeno-carboxamida como inibidores da enzima ikk-2
JP2006500206A JP4568714B2 (ja) 2003-01-15 2004-01-13 酵素ikk−2阻害剤としてのチオフェンカルボキサミド
DK04701632T DK1583756T3 (da) 2003-01-15 2004-01-13 Thiophencarboxamider som inhibitorer af enzymet IKK-2
CNB2004800023046A CN1315820C (zh) 2003-01-15 2004-01-13 作为酶ikk-2抑制剂的噻吩甲酰胺
US10/542,044 US7553868B2 (en) 2003-01-15 2004-01-13 Thiophene carboxamides as inhibitors of the enzyme IKK-2
PT04701632T PT1583756E (pt) 2003-01-15 2004-01-13 Tiofenocarboxamidas como inibidores da enzima ikk-2
DE602004009283T DE602004009283T2 (de) 2003-01-15 2004-01-13 Thiophencarboxamide als inhibitoren des enzyms ikk-2
PCT/GB2004/000106 WO2004063185A1 (en) 2003-01-15 2004-01-13 Thiophene carboxamides as inhibitors of the enzyme ikk-2
AT04701632T ATE374762T1 (de) 2003-01-15 2004-01-13 Thiophencarboxamide als inhibitoren des enzyms ikk-2
MXPA05007340A MXPA05007340A (es) 2003-01-15 2004-01-13 Tiofen carboxamidas como inhibidores de enzima ikk-2.
EP04701632A EP1583756B9 (en) 2003-01-15 2004-01-13 Thiophene carboxamides as inhibitors of the enzyme ikk-2
AU2004203967A AU2004203967B2 (en) 2003-01-15 2004-01-13 Thiophene carboxamides as inhibitors of the enzyme IKK-2
CA002512336A CA2512336A1 (en) 2003-01-15 2004-01-13 Thiophene carboxamides as inhibitors of the enzyme ikk-2
SI200430502T SI1583756T1 (sl) 2003-01-15 2004-01-13 Tiofenski karboksamidi kot inhibitorji encima IKK-2
ZA200505190A ZA200505190B (en) 2003-01-15 2005-06-27 Thiophene carboxamides as inhibitors of the enzyme IKK-2
IL169478A IL169478A (en) 2003-01-15 2005-06-29 Thiophene carboxamides as inhibitors of the enzyme ikk - 2
NO20053810A NO20053810L (no) 2003-01-15 2005-08-12 Thiofenkarboksamider som inhibitorer av enzymet IKK-2
HK06103016A HK1082250A1 (en) 2003-01-15 2006-03-08 Thiophene carboxamides as inhibitors of the enzymeikk-2
CY20071101528T CY1107817T1 (el) 2003-01-15 2007-11-29 Καρβοξαμιδια θειοφαινιου ως αναστολεις του ενζυμου ικκ-2
US12/435,054 US20090215829A1 (en) 2003-01-15 2009-05-04 Thiophene carboxamides as inhibitors of the enzyme ikk-2

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0300091A SE0300091D0 (sv) 2003-01-15 2003-01-15 Novel compounds

Publications (1)

Publication Number Publication Date
SE0300091D0 true SE0300091D0 (sv) 2003-01-15

Family

ID=20290126

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0300091A SE0300091D0 (sv) 2003-01-15 2003-01-15 Novel compounds

Country Status (21)

Country Link
US (2) US7553868B2 (xx)
EP (1) EP1583756B9 (xx)
JP (1) JP4568714B2 (xx)
KR (1) KR20050098248A (xx)
CN (1) CN1315820C (xx)
AT (1) ATE374762T1 (xx)
BR (1) BRPI0406774A (xx)
CA (1) CA2512336A1 (xx)
CY (1) CY1107817T1 (xx)
DE (1) DE602004009283T2 (xx)
DK (1) DK1583756T3 (xx)
ES (1) ES2293206T3 (xx)
HK (1) HK1082250A1 (xx)
IL (1) IL169478A (xx)
MX (1) MXPA05007340A (xx)
NO (1) NO20053810L (xx)
NZ (1) NZ541219A (xx)
PT (1) PT1583756E (xx)
SE (1) SE0300091D0 (xx)
WO (1) WO2004063185A1 (xx)
ZA (1) ZA200505190B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0003154D0 (en) * 2000-02-12 2000-04-05 Astrazeneca Uk Ltd Novel compounds
SE0102616D0 (sv) 2001-07-25 2001-07-25 Astrazeneca Ab Novel compounds
SE0300091D0 (sv) 2003-01-15 2003-01-15 Astrazeneca Ab Novel compounds
SE0300092D0 (sv) * 2003-01-15 2003-01-15 Astrazeneca Ab Novel compounds
RU2006107782A (ru) 2003-08-15 2006-08-10 Астразенека Аб (Se) Замещенные тиофены и их применение
BRPI0418351A (pt) * 2004-01-05 2007-05-08 Astrazeneca Ab composto ou um sal farmaceuticamente aceitável do mesmo, métodos de limitar a proliferação celular em um humano ou animal, de tratamento de um humano ou animal sofrendo de cáncer, de tratamento de profilaxia de cáncer, de tratamento de um humano ou animal sofrendo de uma doença neoplásica, de tratamento de um humano ou animal sofrendo de uma doença prolifetativa de tratamento de cáncer, para o tratamento de infecções associadas com cáncer, para o tratamento profilático de infecções associadas com cáncer, composição farmacêutica, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, método de inibir a chk1 quinase, e, processo para a preparação de um composto ou um sal farmaceuticamente aceitável do mesmo
WO2005105777A1 (en) * 2004-05-05 2005-11-10 Pharmacia & Upjohn Company Llc Substituted thiophene amide compounds for the treatment of inflammation
EP2119703B1 (en) * 2007-01-15 2012-12-12 Santen Pharmaceutical Co., Ltd Novel indole derivative having inhibitory activity on i b kinase
JPWO2009096198A1 (ja) * 2008-02-01 2011-05-26 一般社団法人ファルマIp 新規ビアリール誘導体
BRPI0822522A2 (pt) * 2008-04-23 2018-06-05 Chroma Therapeutics Ltd Inibidores da proteína quinase ikk-beta serina- treonina
US8445529B2 (en) * 2008-07-14 2013-05-21 Santen Pharmaceutical Co., Ltd. Indole derivative having, carbamoyl group, ureido group and substituted oxy group
GB0907120D0 (en) * 2009-04-24 2009-06-03 Chroma Therapeutics Ltd Inhibitors of IKK-ß serine-threonine protein kinase
GB0913345D0 (en) 2009-07-31 2009-09-16 Astrazeneca Ab New combination 802
WO2011061527A1 (en) 2009-11-17 2011-05-26 Astrazeneca Ab Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases
GB201016912D0 (en) 2010-10-07 2010-11-24 Astrazeneca Ab Novel combination
GB201021979D0 (en) 2010-12-23 2011-02-02 Astrazeneca Ab New compound
GB201021992D0 (en) 2010-12-23 2011-02-02 Astrazeneca Ab Compound

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1468012A (en) * 1973-08-09 1977-03-23 Beecham Group Ltd 2-amino-3-carboxy-thiophene derivatives
DE3529247A1 (de) 1985-05-17 1986-11-20 Bayer Ag, 5090 Leverkusen Verwendung von thienylharnstoffen und -isoharnstoffen als leistungsfoerdernde mittel bei tieren, neue thienylharnstoffe und -isoharnstoffe und ihre herstellung
GB2195634B (en) 1986-10-01 1990-08-15 Roussel Lab Ltd Thiophene derivatives
US5258357A (en) 1989-10-07 1993-11-02 Basf Aktiengesellschaft Carboxamides, their preparation and their use as herbicides
US5378703A (en) 1990-04-09 1995-01-03 Alcon Laboratories, Inc. Sulfonamides useful as carbonic anhydrase inhibitors
US5571810A (en) 1990-06-11 1996-11-05 Fujisawa Pharmaceutical Co., Ltd. Thiophene derivatives
US5514801A (en) * 1992-12-29 1996-05-07 Monsanto Company Cyclic sulfone containing retroviral protease inhibitors
WO1998002430A1 (en) 1996-07-11 1998-01-22 Pfizer Pharmaceuticals Inc. Pyridylpyrrole compounds useful as interleukin- and tnf antagonists
PT853083E (pt) 1997-01-06 2001-12-28 Pfizer Composto de piridilfurano e piridiltiofeno e sua utilizacao farmaceutica
US6809088B2 (en) 1997-03-24 2004-10-26 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them
US6117911A (en) * 1997-04-11 2000-09-12 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies
US6037340A (en) 1997-05-28 2000-03-14 Cadus Pharmaceutical Corporation Synthesis and use of thiophene- and pyrrole-based heteroaromatic compounds
DE19744026A1 (de) 1997-10-06 1999-04-08 Hoechst Marion Roussel De Gmbh Pyrazol-Derivate, ihre Herstellung und ihre Verwendung in Arzneimitteln
WO1999046244A1 (en) 1998-03-12 1999-09-16 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (ptpases)
ATE309206T1 (de) * 1998-07-08 2005-11-15 Sanofi Aventis Deutschland Schwefel-substituierte sulfonylaminocarbonsäure n-arylamide, ihre herstellung, ihre anwendung und diese enthaltende pharmazeutische zusammensetzungen
HN2000000051A (es) * 1999-05-19 2001-02-02 Pfizer Prod Inc Derivados heterociclicos utiles como agentes anticancerosos
GB0003154D0 (en) 2000-02-12 2000-04-05 Astrazeneca Uk Ltd Novel compounds
CN100355751C (zh) 2000-03-29 2007-12-19 西克拉塞尔有限公司 2-取代的4-杂芳基-嘧啶、其组合物及其用途
US6414013B1 (en) * 2000-06-19 2002-07-02 Pharmacia & Upjohn S.P.A. Thiophene compounds, process for preparing the same, and pharmaceutical compositions containing the same background of the invention
JP2004523476A (ja) * 2000-10-12 2004-08-05 スミスクライン・ビーチャム・コーポレイション NF−κB阻害剤
US7122544B2 (en) * 2000-12-06 2006-10-17 Signal Pharmaceuticals, Llc Anilinopyrimidine derivatives as IKK inhibitors and compositions and methods related thereto
US20050238911A1 (en) 2001-03-16 2005-10-27 Sturley David K Non-powered luminous panels and devices and method of manufacture
US6713638B2 (en) * 2001-05-18 2004-03-30 Joel M. Linden 2-amino-3-aroyl-4,5 alkylthiophenes: agonist allosteric enhancers at human A1 adenosine receptors
AP1753A (en) * 2001-06-11 2007-07-18 Shire Biochem Inc Thiophene derivatives as antiviral agents for flavvivirus infection
SE0102617D0 (sv) 2001-07-25 2001-07-25 Astrazeneca Ab Novel compounds
SE0102616D0 (sv) 2001-07-25 2001-07-25 Astrazeneca Ab Novel compounds
WO2003029242A1 (en) * 2001-10-04 2003-04-10 Smithkline Beecham Corporation NF-λB INHIBITORS
WO2003028731A1 (en) 2001-10-04 2003-04-10 Smithkline Beecham Corporation Chk1 kinase inhibitors
WO2003029241A1 (en) 2001-10-04 2003-04-10 Smithkline Beecham Corporation Chk1 kinase inhibitors
TWI281916B (en) * 2001-10-25 2007-06-01 Lilly Co Eli Antitumor compounds and methods
US6835745B2 (en) * 2002-01-15 2004-12-28 Wyeth Phenyl substituted thiophenes as estrogenic agents
US7196106B2 (en) * 2002-11-05 2007-03-27 Merck & Co., Inc Cyanothiophene derivatives, compositions containing such compounds and methods of use
SE0300092D0 (sv) 2003-01-15 2003-01-15 Astrazeneca Ab Novel compounds
SE0300091D0 (sv) 2003-01-15 2003-01-15 Astrazeneca Ab Novel compounds

Also Published As

Publication number Publication date
DE602004009283T2 (de) 2008-07-10
JP2006515355A (ja) 2006-05-25
WO2004063185A8 (en) 2004-09-23
MXPA05007340A (es) 2005-09-30
AU2004203967A1 (en) 2004-07-29
NZ541219A (en) 2008-03-28
KR20050098248A (ko) 2005-10-11
HK1082250A1 (en) 2006-06-02
EP1583756B1 (en) 2007-10-03
EP1583756A1 (en) 2005-10-12
DE602004009283D1 (de) 2007-11-15
US7553868B2 (en) 2009-06-30
CY1107817T1 (el) 2013-06-19
US20060111431A1 (en) 2006-05-25
IL169478A0 (en) 2009-02-11
NO20053810D0 (no) 2005-08-12
BRPI0406774A (pt) 2005-12-27
ES2293206T3 (es) 2008-03-16
DK1583756T3 (da) 2007-12-17
ATE374762T1 (de) 2007-10-15
WO2004063185A1 (en) 2004-07-29
CN1315820C (zh) 2007-05-16
CA2512336A1 (en) 2004-07-29
EP1583756B9 (en) 2008-01-09
PT1583756E (pt) 2007-12-03
ZA200505190B (en) 2006-04-26
JP4568714B2 (ja) 2010-10-27
CN1738812A (zh) 2006-02-22
NO20053810L (no) 2005-10-12
US20090215829A1 (en) 2009-08-27
IL169478A (en) 2010-02-17

Similar Documents

Publication Publication Date Title
SE0102616D0 (sv) Novel compounds
HK1082250A1 (en) Thiophene carboxamides as inhibitors of the enzymeikk-2
MXPA04000755A (es) Nuevos compuestos.
SE0202133D0 (sv) Novel compounds
TW200621777A (en) New dihydropteridione derivatives, process for their manufacture and their use as medicament
TW200621262A (en) New dihydropteridione derivatives, process for their manufacture and their use as medicament
GB0003154D0 (en) Novel compounds
SE0302811D0 (sv) Novel compounds
TW200716568A (en) 1H-quinazoline-2,4-diones
SE0300092D0 (sv) Novel compounds
TW200833670A (en) Novel compounds 569
SE0401762D0 (sv) Novel compounds
TW200745122A (en) New compounds I
SE0302139D0 (sv) Novel compounds
SE0303541D0 (sv) New compounds
SE0302116D0 (sv) Novel compounds
TW200730512A (en) Novel compounds
DE602004029355D1 (de) Sulfopyrrolderivate
TW200722418A (en) Novel compounds
SE0303280D0 (sv) Novel compounds
SE0303090D0 (sv) Novel compounds
SE0302755D0 (sv) Novel compounds
SE0300117D0 (sv) Novel Compounds
SE0002330D0 (sv) Novel compounds
SE0004480D0 (sv) Novel compounds