ZA200504804B - Topical anti-infective formulations - Google Patents
Topical anti-infective formulations Download PDFInfo
- Publication number
- ZA200504804B ZA200504804B ZA200504804A ZA200504804A ZA200504804B ZA 200504804 B ZA200504804 B ZA 200504804B ZA 200504804 A ZA200504804 A ZA 200504804A ZA 200504804 A ZA200504804 A ZA 200504804A ZA 200504804 B ZA200504804 B ZA 200504804B
- Authority
- ZA
- South Africa
- Prior art keywords
- topical
- lysostaphin
- topical composition
- cream
- nisin
- Prior art date
Links
- 230000000699 topical effect Effects 0.000 title claims description 80
- 239000002626 anti infective formulation Substances 0.000 title description 2
- 239000000203 mixture Substances 0.000 claims description 77
- 108090000988 Lysostaphin Proteins 0.000 claims description 74
- 108010053775 Nisin Proteins 0.000 claims description 44
- NVNLLIYOARQCIX-MSHCCFNRSA-N Nisin Chemical compound N1C(=O)[C@@H](CC(C)C)NC(=O)C(=C)NC(=O)[C@@H]([C@H](C)CC)NC(=O)[C@@H](NC(=O)C(=C/C)/NC(=O)[C@H](N)[C@H](C)CC)CSC[C@@H]1C(=O)N[C@@H]1C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@@H](C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(NCC(=O)N[C@H](C)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCSC)C(=O)NCC(=O)N[C@H](CS[C@@H]2C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H](CCSC)C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(N[C@H](C)C(=O)N[C@@H]3C(=O)N[C@@H](C(N[C@H](CC=4NC=NC=4)C(=O)N[C@H](CS[C@@H]3C)C(=O)N[C@H](CO)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H](CC=3NC=NC=3)C(=O)N[C@H](C(C)C)C(=O)NC(=C)C(=O)N[C@H](CCCCN)C(O)=O)=O)CS[C@@H]2C)=O)=O)CS[C@@H]1C NVNLLIYOARQCIX-MSHCCFNRSA-N 0.000 claims description 44
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Landscapes
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| AU (1) | AU2003296937A1 (fr) |
| BR (1) | BR0316776A (fr) |
| CA (1) | CA2508796A1 (fr) |
| EA (1) | EA200500804A1 (fr) |
| IL (1) | IL169117A0 (fr) |
| WO (1) | WO2004052308A2 (fr) |
| ZA (1) | ZA200504804B (fr) |
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| US20050058673A1 (en) | 2003-09-09 | 2005-03-17 | 3M Innovative Properties Company | Antimicrobial compositions and methods |
| WO2005107787A1 (fr) * | 2004-05-06 | 2005-11-17 | Molichem Medicines, Inc. | Traitement de maladies et troubles associes aux membranes au moyen de compositions contenant des lantibiotiques |
| US9028852B2 (en) | 2004-09-07 | 2015-05-12 | 3M Innovative Properties Company | Cationic antiseptic compositions and methods of use |
| PL1857120T3 (pl) * | 2005-01-19 | 2012-05-31 | Nippon Zenyaku Kogyo Co Ltd | Infuzje do leczenia zapalenia gruczołów mlekowych |
| EP1858482B1 (fr) * | 2005-03-10 | 2014-04-23 | 3M Innovative Properties Company | Methodes de reduction d'une contamination microbienne |
| BRPI0608691A2 (pt) | 2005-03-10 | 2010-12-07 | 3M Innovative Properties Co | composição antimicrobiana, e, métodos para matar ou inativar microorganismos em tecido da mucosa de um mamìfero, para tratar uma lesão ou ferimento infectado, para descolonização de microorganismos, para proporcionar eficácia antimicrobiana residual sobre uma superfìcie e para tratar uma condição |
| EP1885403B1 (fr) | 2005-04-12 | 2013-05-08 | Nektar Therapeutics | Conjugués de la lysostaphine et du poly(éthylène glycol) |
| WO2006120494A1 (fr) * | 2005-05-13 | 2006-11-16 | Advanced Scientific Developements | Combinaison pharmaceutique comprenant un antibacterien et une substance active choisie parmi le carveol, le thymol, l’eugenol, le borneol et les carvacrol |
| WO2006120495A1 (fr) * | 2005-05-13 | 2006-11-16 | Advanced Scientific Developements | Composition pharmaceutique comprenant un antiviral, an antitumoral ou un antiparasitaire, et un actif choisi parmi le carveol, le thymol, l’eugenol, le borneol et le carvacrol |
| US7517852B2 (en) * | 2005-07-28 | 2009-04-14 | Biosynexus Incorporated | Compositions and methods for treating bacteria |
| WO2007044745A1 (fr) * | 2005-10-11 | 2007-04-19 | Biosynexus Incorporated | Compositions de lantibiotiques et de mupirocine pour le traitement des infections bacteriennes |
| US20070238652A1 (en) * | 2006-02-08 | 2007-10-11 | Biosynexus Incorporated | Neutralization of bacterial spores |
| ATE470451T1 (de) | 2006-03-31 | 2010-06-15 | Univ St Andrews | Antimikrobielle zusammensetzungen mit einem kationischen peptid und glycylglycin- endopeptidase |
| DE102007030931A1 (de) * | 2007-07-03 | 2009-01-08 | Birgit Riesinger | Zusammensetzung, enthaltend mindestens einen nutritiven, mindestens einen desinfizierenden bzw. dekontaminierenden und/oder mindestens einen Proteasen hemmend wirkenden Wirkstoff und/oder Wirkstoffkomplex |
| JP2010534063A (ja) | 2007-07-20 | 2010-11-04 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | ランチビオティックス及びこれらの使用 |
| EP2625957A1 (fr) | 2007-12-31 | 2013-08-14 | 3M Innovative Properties Company | Compositions antimicrobiennes |
| WO2009114520A2 (fr) * | 2008-03-10 | 2009-09-17 | Pharmain Corporation | Compositions de traitement ayant des métallopeptidases, procédés de fabrication et utilisation de celles-ci |
| AU2011315525B2 (en) * | 2010-10-12 | 2016-05-12 | Consumo Em Verde - Biotecnologia Das Plantas, S.A. | Antimicrobial protein |
| RU2540467C1 (ru) * | 2013-07-16 | 2015-02-10 | Государственное научное учреждение Институт экспериментальной ветеринарии Сибири и Дальнего Востока Российской академии сельскохозяйственных наук (ГНУ ИЭВСиДВ Россельхозакадемии) | Сульфогель-препарат для лечения инфицированных ран в области пальцев животных и способ его применения |
| EP3143137A4 (fr) | 2014-05-14 | 2017-11-15 | Trustees of Dartmouth College | Lysostaphine désimmunisée et méthodes d'utilisation |
| CN107920510A (zh) * | 2015-08-24 | 2018-04-17 | 史密夫和内修有限公司 | 中等极性油与抗菌剂的组合在细菌生物膜上的协同抗菌活性 |
| CN106860401A (zh) * | 2017-02-09 | 2017-06-20 | 林映津 | 一种纯天然伤口修复剂 |
| KR102195998B1 (ko) * | 2019-09-27 | 2020-12-29 | 코스맥스 주식회사 | 스타필로코커스 시뮬란스 st-9 균주 및 그의 피부 상태 개선 용도 |
| IT201900021882A1 (it) * | 2019-11-22 | 2021-05-22 | Sterify S R L | Soluzione lantibiotica contro le infezioni batteriche |
| CN112715819A (zh) * | 2020-12-08 | 2021-04-30 | 山东元泰生物工程有限公司 | 一种杀菌剂及其应用 |
| CN114634959B (zh) * | 2022-04-02 | 2024-02-02 | 中国科学院兰州化学物理研究所 | 一种双功能仿生润滑剂及其制备方法和应用 |
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| US5858962A (en) * | 1987-05-11 | 1999-01-12 | Ambi Inc. | Composition for treating mastitis and other staphylococcal infections |
| US5260271A (en) * | 1988-06-22 | 1993-11-09 | Applied Microbiology, Inc. | Nisin compositions for use as enhanced broad range bactericides |
| US5217950A (en) * | 1988-06-22 | 1993-06-08 | Applied Microbiology, Inc. | Nisin compositions for use as enhanced, broad range bactericides |
| AU631803B2 (en) * | 1988-06-22 | 1992-12-10 | Applied Microbiology, Inc | Nisin compositions for use as enhanced, broad range bactericides |
| US4980163A (en) * | 1989-03-01 | 1990-12-25 | Public Health Research Institute Of The City Of New York | Novel bacteriocin compositions for use as enhanced broad range bactericides and methods of preventing and treating microbial infection |
| US5139786A (en) * | 1989-07-07 | 1992-08-18 | Ciba-Geigy Corporation | Topical formulations |
| US5342612A (en) * | 1991-12-20 | 1994-08-30 | American Cyanamid Company | Compositions for the treatment of mammalian diseases |
| JP2538513B2 (ja) * | 1993-11-01 | 1996-09-25 | 久光製薬株式会社 | 吸収促進剤および該吸収促進剤を含有する外用製剤 |
| GB9423404D0 (en) * | 1994-11-19 | 1995-01-11 | Biotech & Biolog Scien Res | Production of nisin |
| US5762948A (en) * | 1995-06-07 | 1998-06-09 | Ambi Inc. | Moist bacteriocin disinfectant wipes and methods of using the same |
| US5866539A (en) * | 1995-06-23 | 1999-02-02 | Ambi Inc. | Method for the control of antibiotic-resistant gram positive bacteria and treatment of infection |
| US5804549A (en) * | 1996-01-05 | 1998-09-08 | Ambi Inc. | Compositions with activity against helicobacter |
| US5795909A (en) * | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
| US6503881B2 (en) * | 1996-08-21 | 2003-01-07 | Micrologix Biotech Inc. | Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics |
| US5910479A (en) * | 1996-10-18 | 1999-06-08 | Ambi Inc. | Method for the treatment of Streptococcus pneumoniae infection |
| US5985823A (en) * | 1997-06-09 | 1999-11-16 | Ambi Inc. | Method for the treatment of diarrheal disease and for eliminating particular bacterial populations from the colon |
| SK732000A3 (en) * | 1997-07-23 | 2001-03-12 | Ambi Inc | Pharmaceutical compositions containing lysostaphin alone or in combination with an antibiotic for the treatment of staphylococcal infections |
| US6028051A (en) * | 1997-07-23 | 2000-02-22 | Ambi Inc. | Method for the treatment of staphylococcal disease |
| US6056954A (en) * | 1997-10-31 | 2000-05-02 | New Horizons Diagnostics Corp | Use of bacterial phage associated lysing enzymers for the prophylactic and therapeutic treatment of various illnesses |
| US6248324B1 (en) * | 1997-10-31 | 2001-06-19 | Vincent Fischetti | Bacterial phage associated lysing enzymes for treating dermatological infections |
| WO2000053226A1 (fr) * | 1999-03-11 | 2000-09-14 | Saitama Daiichi Pharmaceutical Co., Ltd. | Compositions facilitant l'absorption cutanee |
| US6315996B1 (en) * | 1999-04-09 | 2001-11-13 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Topical lysostaphin therapy for staphylococcus ocular infections |
| US6056955A (en) * | 1999-09-14 | 2000-05-02 | Fischetti; Vincent | Topical treatment of streptococcal infections |
| US20030211995A1 (en) * | 2001-12-21 | 2003-11-13 | Kokai-Kun John Fitzgerald | Methods and formulations for eradicating or alleviating staphylococcal nasal colonization using lysostaphin |
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2003
- 2003-12-10 CA CA002508796A patent/CA2508796A1/fr not_active Abandoned
- 2003-12-10 US US10/733,046 patent/US20040192581A1/en not_active Abandoned
- 2003-12-10 EP EP03812962A patent/EP1585532A4/fr not_active Withdrawn
- 2003-12-10 BR BR0316776-3A patent/BR0316776A/pt not_active Application Discontinuation
- 2003-12-10 CN CNA2003801095969A patent/CN1744905A/zh active Pending
- 2003-12-10 AP AP2005003346A patent/AP2005003346A0/xx unknown
- 2003-12-10 JP JP2004558711A patent/JP2006514944A/ja active Pending
- 2003-12-10 WO PCT/US2003/039479 patent/WO2004052308A2/fr active Application Filing
- 2003-12-10 EA EA200500804A patent/EA200500804A1/ru unknown
- 2003-12-10 AU AU2003296937A patent/AU2003296937A1/en not_active Abandoned
-
2005
- 2005-06-09 IL IL169117A patent/IL169117A0/en unknown
- 2005-06-13 ZA ZA200504804A patent/ZA200504804B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL169117A0 (en) | 2009-02-11 |
| AP2005003346A0 (en) | 2005-06-30 |
| EA200500804A1 (ru) | 2005-12-29 |
| EP1585532A4 (fr) | 2008-09-24 |
| CN1744905A (zh) | 2006-03-08 |
| US20040192581A1 (en) | 2004-09-30 |
| WO2004052308A2 (fr) | 2004-06-24 |
| JP2006514944A (ja) | 2006-05-18 |
| WO2004052308A3 (fr) | 2004-09-30 |
| BR0316776A (pt) | 2005-10-25 |
| CA2508796A1 (fr) | 2004-06-24 |
| AU2003296937A1 (en) | 2004-06-30 |
| EP1585532A2 (fr) | 2005-10-19 |
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